Aneuploidy-induced proteotoxic stress can be effectively tolerated without dosage compensation, genetic mutations, or stress responses
Background: The protein homeostasis (proteostasis) network maintains balanced protein synthesis, folding, transport, and degradation within a cell. Failure to maintain proteostasis is associated with aging and disease, leading to concerted efforts to study how the network responds to various proteotoxic stresses. This is often accomplished using ectopic overexpression of well-characterized, model misfolded protein substrates.
However, how cells tolerate large-scale, diverse burden to the proteostasis network is not understood. Aneuploidy, the state of imbalanced chromosome content, adversely affects the proteostasis network by dysregulating the expression of hundreds of proteins simultaneously. Using aneuploid haploid yeast cells as a model, we address whether cells can tolerate large-scale, diverse challenges to the proteostasis network.
Results: Here we characterize several aneuploid Saccharomyces cerevisiae strains isolated from a collection of stable, randomly generated yeast aneuploid cells. These strains exhibit robust growth and resistance to multiple drugs which induce various forms of proteotoxic stress.
Whole genome re-sequencing of the strains revealed this was not the result of genetic mutations, and transcriptome profiling combined with ribosome footprinting showed that genes are expressed and translated in accordance to chromosome copy number. In some strains, various facets of the proteostasis network are mildly upregulated without chronic activation of environmental stress response or heat shock response pathways.
No severe defects were observed in the degradation of misfolded proteins, using model misfolded substrates of endoplasmic reticulum-associated degradation or cytosolic quality control pathways, and protein biosynthesis capacity was not impaired.
Conclusions: We show that yeast strains of some karyotypes in the genetic background studied here can tolerate the large aneuploidy-associated burden to the proteostasis machinery without genetic changes, dosage compensation, or activation of canonical stress response pathways.
We suggest that proteotoxic stress, while common, is not always an obligate consequence of aneuploidy, but rather certain karyotypes and genetic backgrounds may be able to tolerate the excess protein burden placed on the protein homeostasis machinery. This may help clarify how cancer cells are paradoxically both highly aneuploid and highly proliferative at the same time.
Pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E07E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Porcine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E07E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Porcine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E07E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Porcine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog E3 ubiquitin protein ligase CHIP ELISA kit |
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| E08E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Canine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog E3 ubiquitin protein ligase CHIP ELISA kit |
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| E08E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Canine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog E3 ubiquitin protein ligase CHIP ELISA kit |
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| E08E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Canine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat E3 ubiquitin protein ligase CHIP ELISA kit |
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| E06E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Goat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat E3 ubiquitin protein ligase CHIP ELISA kit |
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| E06E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Goat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Goat E3 ubiquitin protein ligase CHIP ELISA kit |
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| E06E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Goat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human E3 ubiquitin protein ligase CHIP ELISA kit |
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| E01E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Human E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human E3 ubiquitin protein ligase CHIP ELISA kit |
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| E01E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Human E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human E3 ubiquitin protein ligase CHIP ELISA kit |
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| E01E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Human E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse E3 ubiquitin protein ligase CHIP ELISA kit |
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| E03E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Mouse E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse E3 ubiquitin protein ligase CHIP ELISA kit |
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| E03E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Mouse E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse E3 ubiquitin protein ligase CHIP ELISA kit |
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| E03E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Mouse E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit E3 ubiquitin protein ligase CHIP ELISA kit |
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| E04E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Rabbit E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit E3 ubiquitin protein ligase CHIP ELISA kit |
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| E04E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Rabbit E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit E3 ubiquitin protein ligase CHIP ELISA kit |
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| E04E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Rabbit E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey E3 ubiquitin protein ligase CHIP ELISA kit |
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| E09E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Monkey E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey E3 ubiquitin protein ligase CHIP ELISA kit |
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| E09E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Monkey E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Monkey E3 ubiquitin protein ligase CHIP ELISA kit |
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| E09E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Monkey E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Guinea pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E05E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Guinea pig E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Guinea pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E05E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Guinea pig E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Guinea pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E05E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Guinea pig E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Human E3 ubiquitin- protein ligase CHIP, STUB1 ELISA KIT |
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| ELI-50737h | Lifescience Market | 96 Tests | EUR 988.8 |
Carboxy Terminus of Hsp70-Interacting Protein (CHIP) Antibody |
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| 20-abx142251 | Abbexa |
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EpiQuik Methyl-CpG Binding Domain Protein 2 ChIP Kit |
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| P-2017 | EpiGentek |
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Human CHIP Antibody |
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| 32585-05111 | AssayPro | 150 ug | EUR 313.2 |
STUB1/CHIP Antibody |
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| AF6514 | Affbiotech | 100ul | EUR 420 |
STUB1/CHIP Antibody |
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| DF6303 | Affbiotech | 200ul | EUR 420 |
CHIP, human recombinant |
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| 4898-25 | Biovision | each | EUR 418.8 |
CHIP Polyclonal Antibody |
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| ABP58142-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
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| ABP58142-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
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| ABP58142-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
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| ES11301-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against CHIP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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CHIP Polyclonal Antibody |
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| ES11301-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against CHIP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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EpiQuik Tissue Methyl-CpG Binding Domain Protein 2 ChIP Kit |
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| P-2018 | EpiGentek | 48 Reactions | EUR 1067.46 |
EpiQuik Plant ChIP Kit |
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| P-2014 | EpiGentek |
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Anti-STUB1 / CHIP antibody |
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| STJ70128 | St John's Laboratory | 100 µg | EUR 430.8 |
Polyclonal STUB1 / CHIP Antibody |
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| AMM08034G | Leading Biology | 0.05ml | EUR 580.8 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human STUB1 / CHIP . This antibody is tested and proven to work in the following applications: |
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ChromaFlash One-Step ChIP Kit |
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| P-2025 | EpiGentek |
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Anti-RIP140 Antibody ChIP grade |
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| STJ502791 | St John's Laboratory | 100 µg | EUR 571.2 |
Phospho-STUB1/CHIP (Ser19) Antibody |
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| AF3514 | Affbiotech | 100ul | EUR 540 |
Human CHIP Antibody (Biotin Conjugate) |
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| 32585-05121 | AssayPro | 150 ug | EUR 442.8 |
ChromaFlash High-Sensitivity ChIP Kit |
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| P-2027 | EpiGentek |
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Anti-Histone H2B - ChIP Grade (4G6) |
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| YF-MA16342 | Abfrontier | 100 ug | EUR 435.6 |
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Description: Mouse monoclonal to Histone H2B - ChIP Grade |
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EpiQuik Chromatin Immunoprecipitation (ChIP) Kit |
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| P-2002 | EpiGentek |
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EpiQuik Acetyl-Histone H3 ChIP Kit |
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| P-2010 | EpiGentek |
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EpiQuik Acetyl-Histone H4 ChIP Kit |
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| P-2011 | EpiGentek |
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EpiQuik Methyl-Histone H3K9 ChIP Kit |
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| P-2006 | EpiGentek |
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EpiQuik Methyl-Histone H3K4 ChIP Kit |
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| P-2007 | EpiGentek |
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EpiQuik Methyl-Histone H3K27 ChIP Kit |
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| P-2015 | EpiGentek |
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Pre-Sure ChIP Antibody Validation Kit |
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| P-2031 | EpiGentek |
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ChromaFlash One-Step Magnetic ChIP Kit |
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| P-2026 | EpiGentek |
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Polyclonal Goat Anti-STUB1 / CHIP Antibody |
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| APR16403G | Leading Biology | 0.1 mg | EUR 580.8 |
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Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-STUB1 / CHIP . This antibody is tested and proven to work in the following applications: |
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Polyclonal STUB1 / CHIP Antibody (C-Terminus) |
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| AMM08035G | Leading Biology | 0.05mg | EUR 580.8 |
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Description: A polyclonal antibody raised in Goat that recognizes and binds to Human STUB1 / CHIP (C-Terminus). This antibody is tested and proven to work in the following applications: |
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Human CHIP AssayLite Antibody (RPE Conjugate) |
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| 32585-05151 | AssayPro | 150 ug | EUR 513.6 |
Human CHIP AssayLite Antibody (APC Conjugate) |
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| 32585-05161 | AssayPro | 150 ug | EUR 513.6 |
Human CHIP AssayLite Antibody (FITC Conjugate) |
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| 32585-05141 | AssayPro | 150 ug | EUR 513.6 |
Human CHIP AssayLite Antibody (PerCP Conjugate) |
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| 32585-05171 | AssayPro | 150 ug | EUR 565.2 |
EpiQuik Tissue Chromatin Immunoprecipitation (ChIP) Kit |
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| P-2003 | EpiGentek |
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EpiQuik Tissue Acetyl-Histone H3 ChIP Kit |
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| P-2012 | EpiGentek |
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EpiQuik Tissue Acetyl-Histone H4 ChIP Kit |
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| P-2013 | EpiGentek |
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ELISA kit for Human E3 ubiquitin-protein ligase CHIP |
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| EK4512 | SAB | 96 tests | EUR 663.6 |
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Description: Enzyme-linked immunosorbent assay kit for quantification of Human E3 ubiquitin-protein ligase CHIP in samples from serum, plasma, tissue homogenates and other biological fluids. |
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EpiQuik Tri-Methyl-Histone H3K9 ChIP Kit |
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| P-2006T | EpiGentek |
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EpiQuik Tissue Methyl-Histone H3K9 ChIP Kit |
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| P-2008 | EpiGentek |
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EpiQuik Tissue Methyl-Histone H3K4 ChIP Kit |
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| P-2009 | EpiGentek |
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Human E3 ubiquitin-protein ligase CHIP(STUB1) ELISA kit |
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| CSB-EL022887HU-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human E3 ubiquitin-protein ligase CHIP(STUB1) ELISA kit |
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| 1-CSB-EL022887HU | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human E3 ubiquitin-protein ligase CHIP(STUB1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Mouse STUB1(E3 ubiquitin-protein ligase CHIP) ELISA Kit |
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| EM1381 | FN Test | 96T | EUR 628.92 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
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Human STUB1/ E3 ubiquitin-protein ligase CHIP ELISA Kit |
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| E2420Hu | Sunlong | 1 Kit | EUR 685.2 |
Human STUB1(E3 ubiquitin-protein ligase CHIP) ELISA Kit |
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| EH3833 | FN Test | 96T | EUR 628.92 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
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EpiQuik Tissue Methyl-Histone H3K27 ChIP Kit |
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| P-2016 | EpiGentek |
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EpiNext ChIP-Seq High-Sensitivity Kit (Illumina) |
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| P-2030 | EpiGentek |
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ELISA kit for Human STUB1 (E3 ubiquitin-protein ligase CHIP) |
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| E-EL-H5533 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
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Description: A sandwich ELISA kit for quantitative measurement of Human STUB1 (E3 ubiquitin-protein ligase CHIP) in samples from Serum, Plasma, Cell supernatant |
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ELISA kit for Human E3 ubiquitin-protein ligase CHIP (STUB1) |
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| KTE60397-48T | Abbkine | 48T | EUR 398.4 |
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Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human E3 ubiquitin-protein ligase CHIP (STUB1) |
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| KTE60397-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
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Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human E3 ubiquitin-protein ligase CHIP (STUB1) |
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| KTE60397-96T | Abbkine | 96T | EUR 646.8 |
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Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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STUB1 ELISA Kit| Mouse E3 ubiquitin-protein ligase CHIP ELISA Ki |
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| EF013909 | Lifescience Market | 96 Tests | EUR 826.8 |
Rabbit IgG (non-immune, isotype control, CHIP/IP grade) |
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| 20009-1-CH | Alpha Diagnostics | 100 ug | EUR 270 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pG-Tn5) |
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| TD901-01 | Vazyme | 12 rxn | EUR 1195.2 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pG-Tn5) |
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| TD901-02 | Vazyme | 48 rxn | EUR 4153.2 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pA-Tn5) |
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| TD902-01 | Vazyme | 12 rxn | EUR 1195.2 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pA-Tn5) |
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| TD902-02 | Vazyme | 48 rxn | EUR 4153.2 |
MiniTurbo with 8-Well Sample Block (MiniTurbo Writer Programmable Chip and software included) |
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| MOL2706 | Scientific Laboratory Supplies | EACH | EUR 2160.77 |
Anti-CHIP antibody |
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| STJ192459 | St John's Laboratory | 200 µl | EUR 236.4 |
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Description: Unconjugated Rabbit polyclonal to CHIP |
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pCMV-HA-chip Plasmid |
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| PVTB00025-2a | Lifescience Market | 2 ug | EUR 427.2 |
pcDNA3.0-Flag-CHIP Plasmid |
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| PVTB00152-2b | Lifescience Market | 2 ug | EUR 427.2 |
pcDNA3.0-EGFP-CHIP Plasmid |
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| PVTB00152-2c | Lifescience Market | 2 ug | EUR 427.2 |
pcDNA3.0-HA-CHIP Plasmid |
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| PVTB00152-2d | Lifescience Market | 2 ug | EUR 427.2 |
Human Chitinase 3 Like Protein 2 (CHI3L2) Protein |
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| 20-abx165963 | Abbexa |
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CHI3L2 protein |
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| 80R-4391 | Fitzgerald | 50 ug | EUR 418.8 |
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Description: Purified Recombinant CHI3L2 protein |
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Recombinant Human Chitinase-3-like protein 1/CHI3L1 Protein |
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| RP00521 | Abclonal | 10 μg | EUR 196.8 |
CHI3L1 protein (His tag) |
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| 80R-2666 | Fitzgerald | 10 ug | EUR 224.4 |
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Description: Purified recombinant Human CHI3L1 protein (His tag) |
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Chicken C Reactive Protein (CRP) Protein |
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| 20-abx165887 | Abbexa |
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CHI3L1 Recombinant Protein (Rat) |
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| RP194828 | ABM | 100 ug | Ask for price |
Chi3l3 Recombinant Protein (Rat) |
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| RP194831 | ABM | 100 ug | Ask for price |
Chicken IgG protein |
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| 31R-1070 | Fitzgerald | 10 mg | EUR 392.4 |
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Description: Purified native Chicken IgG protein |
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Quantitative genetic architecture of adaptive phenology traits in the deciduous tree, Populus trichocarpa (Torr. and Gray)
In a warming climate, the ability to accurately predict and track shifting environmental conditions will be fundamental for plant survival. Environmental cues define the transitions between growth and dormancy as plants synchronise development with favourable environmental conditions, however these cues are predicted to change under future climate projections which may have profound impacts on tree survival and growth.
Here, we use a quantitative genetic approach to estimate the genetic basis of spring and autumn phenology in Populus trichocarpa to determine this species capacity for climate adaptation. We measured bud burst, leaf coloration, and leaf senescence traits across two years (2017-2018) and combine these observations with measures of lifetime growth to determine how genetic correlations between phenology and growth may facilitate or constrain adaptation.
Timing of transitions differed between years, although we found strong cross year genetic correlations in all traits, suggesting that genotypes respond in consistent ways to seasonal cues. Spring and autumn phenology were correlated with lifetime growth, where genotypes that burst leaves early and shed them late had the highest lifetime growth.
We also identified substantial heritable variation in the timing of all phenological transitions (h2 = 0.5-0.8) and in lifetime growth (h2 = 0.8). The combination of additive variation and favourable genetic correlations in phenology traits suggests that populations of cultivated varieties of P. Trichocarpa may have the capability to adapt their phenology to climatic changes without negative impacts on growth.
Gut Microbiota between Environment and Genetic Background in Familial Mediterranean Fever (FMF)
The gastrointestinal tract hosts the natural reservoir of microbiota since birth. The microbiota includes various bacteria that establish a progressively mutual relationship with the host. Of note, the composition of gut microbiota is rather individual-specific and, normally, depends on both the host genotype and environmental factors.
The study of the bacterial profile in the gut demonstrates that dominant and minor phyla are present in the gastrointestinal tract with bacterial density gradually increasing in oro-aboral direction. The cross-talk between bacteria and host within the gut strongly contributes to the host metabolism, to structural and protective functions. Dysbiosis can develop following aging, diseases, inflammatory status, and antibiotic therapy. Growing evidences show a possible link between the microbiota and Familial Mediterranean Fever (FMF), through a shift of the relative abundance in microbial species.
To which extent such perturbations of the microbiota are relevant in driving the phenotypic manifestations of FMF with respect to genetic background, remains to be further investigated.
Rat E3 ubiquitin protein ligase CHIP ELISA kit |
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| E02E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Rat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rat E3 ubiquitin protein ligase CHIP ELISA kit |
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| E02E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Rat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E07E0405-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Porcine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig E3 ubiquitin protein ligase CHIP ELISA kit |
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| E07E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Porcine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Pig E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E07E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Porcine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E08E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Canine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E08E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Canine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Dog E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E08E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Canine E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Goat E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E06E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Goat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Goat E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E06E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Goat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Goat E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E06E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Goat E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Human E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E01E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Human E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Human E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E01E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Human E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Human E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E01E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Human E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Mouse E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E03E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Mouse E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Mouse E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E03E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Mouse E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Mouse E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E03E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Mouse E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E04E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E04E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
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Rabbit E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E04E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Rabbit E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Monkey E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E09E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Monkey E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Monkey E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E09E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Monkey E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Monkey E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E09E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Monkey E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Guinea pig E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E05E0405-192T | BlueGene | 192 tests | EUR 1524 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Guinea pig E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E05E0405-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Guinea pig E3 ubiquitin protein ligase CHIP ELISA kit |
|||
| E05E0405-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
|
Description: A competitive ELISA for quantitative measurement of Guinea pig E3 ubiquitin protein ligase CHIP in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
|||
Human E3 ubiquitin- protein ligase CHIP, STUB1 ELISA KIT |
|||
| ELI-50737h | Lifescience Market | 96 Tests | EUR 988.8 |
Carboxy Terminus of Hsp70-Interacting Protein (CHIP) Antibody |
|||
| 20-abx142251 | Abbexa |
|
|
EpiQuik Methyl-CpG Binding Domain Protein 2 ChIP Kit |
|||
| P-2017 | EpiGentek |
|
|
Human CHIP Antibody |
|||
| 32585-05111 | AssayPro | 150 ug | EUR 313.2 |
STUB1/CHIP Antibody |
|||
| AF6514 | Affbiotech | 100ul | EUR 420 |
STUB1/CHIP Antibody |
|||
| DF6303 | Affbiotech | 200ul | EUR 420 |
CHIP, human recombinant |
|||
| 4898-25 | Biovision | each | EUR 418.8 |
CHIP Polyclonal Antibody |
|||
| ABP58142-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
|||
| ABP58142-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
|||
CHIP Polyclonal Antibody |
|||
| ABP58142-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
|||
CHIP Polyclonal Antibody |
|||
| ES11301-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against CHIP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
CHIP Polyclonal Antibody |
|||
| ES11301-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against CHIP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
EpiQuik Tissue Methyl-CpG Binding Domain Protein 2 ChIP Kit |
|||
| P-2018 | EpiGentek | 48 Reactions | EUR 1067.46 |
EpiQuik Plant ChIP Kit |
|||
| P-2014 | EpiGentek |
|
|
Anti-STUB1 / CHIP antibody |
|||
| STJ70128 | St John's Laboratory | 100 µg | EUR 430.8 |
Polyclonal STUB1 / CHIP Antibody |
|||
| AMM08034G | Leading Biology | 0.05ml | EUR 580.8 |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human STUB1 / CHIP . This antibody is tested and proven to work in the following applications: |
|||
ChromaFlash One-Step ChIP Kit |
|||
| P-2025 | EpiGentek |
|
|
Anti-RIP140 Antibody ChIP grade |
|||
| STJ502791 | St John's Laboratory | 100 µg | EUR 571.2 |
Phospho-STUB1/CHIP (Ser19) Antibody |
|||
| AF3514 | Affbiotech | 100ul | EUR 540 |
Human CHIP Antibody (Biotin Conjugate) |
|||
| 32585-05121 | AssayPro | 150 ug | EUR 442.8 |
ChromaFlash High-Sensitivity ChIP Kit |
|||
| P-2027 | EpiGentek |
|
|
Anti-Histone H2B - ChIP Grade (4G6) |
|||
| YF-MA16342 | Abfrontier | 100 ug | EUR 435.6 |
|
Description: Mouse monoclonal to Histone H2B - ChIP Grade |
|||
EpiQuik Chromatin Immunoprecipitation (ChIP) Kit |
|||
| P-2002 | EpiGentek |
|
|
EpiQuik Acetyl-Histone H3 ChIP Kit |
|||
| P-2010 | EpiGentek |
|
|
EpiQuik Acetyl-Histone H4 ChIP Kit |
|||
| P-2011 | EpiGentek |
|
|
EpiQuik Methyl-Histone H3K9 ChIP Kit |
|||
| P-2006 | EpiGentek |
|
|
EpiQuik Methyl-Histone H3K4 ChIP Kit |
|||
| P-2007 | EpiGentek |
|
|
EpiQuik Methyl-Histone H3K27 ChIP Kit |
|||
| P-2015 | EpiGentek |
|
|
Pre-Sure ChIP Antibody Validation Kit |
|||
| P-2031 | EpiGentek |
|
|
ChromaFlash One-Step Magnetic ChIP Kit |
|||
| P-2026 | EpiGentek |
|
|
Polyclonal Goat Anti-STUB1 / CHIP Antibody |
|||
| APR16403G | Leading Biology | 0.1 mg | EUR 580.8 |
|
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-STUB1 / CHIP . This antibody is tested and proven to work in the following applications: |
|||
Polyclonal STUB1 / CHIP Antibody (C-Terminus) |
|||
| AMM08035G | Leading Biology | 0.05mg | EUR 580.8 |
|
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human STUB1 / CHIP (C-Terminus). This antibody is tested and proven to work in the following applications: |
|||
Human CHIP AssayLite Antibody (RPE Conjugate) |
|||
| 32585-05151 | AssayPro | 150 ug | EUR 513.6 |
Human CHIP AssayLite Antibody (APC Conjugate) |
|||
| 32585-05161 | AssayPro | 150 ug | EUR 513.6 |
Human CHIP AssayLite Antibody (FITC Conjugate) |
|||
| 32585-05141 | AssayPro | 150 ug | EUR 513.6 |
Human CHIP AssayLite Antibody (PerCP Conjugate) |
|||
| 32585-05171 | AssayPro | 150 ug | EUR 565.2 |
EpiQuik Tissue Chromatin Immunoprecipitation (ChIP) Kit |
|||
| P-2003 | EpiGentek |
|
|
EpiQuik Tissue Acetyl-Histone H3 ChIP Kit |
|||
| P-2012 | EpiGentek |
|
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EpiQuik Tissue Acetyl-Histone H4 ChIP Kit |
|||
| P-2013 | EpiGentek |
|
|
ELISA kit for Human E3 ubiquitin-protein ligase CHIP |
|||
| EK4512 | SAB | 96 tests | EUR 663.6 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Human E3 ubiquitin-protein ligase CHIP in samples from serum, plasma, tissue homogenates and other biological fluids. |
|||
EpiQuik Tri-Methyl-Histone H3K9 ChIP Kit |
|||
| P-2006T | EpiGentek |
|
|
EpiQuik Tissue Methyl-Histone H3K9 ChIP Kit |
|||
| P-2008 | EpiGentek |
|
|
EpiQuik Tissue Methyl-Histone H3K4 ChIP Kit |
|||
| P-2009 | EpiGentek |
|
|
Human E3 ubiquitin-protein ligase CHIP(STUB1) ELISA kit |
|||
| CSB-EL022887HU-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
|
Description: Quantitativesandwich ELISA kit for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Human E3 ubiquitin-protein ligase CHIP(STUB1) ELISA kit |
|||
| 1-CSB-EL022887HU | Cusabio |
|
|
|
Description: Quantitativesandwich ELISA kit for measuring Human E3 ubiquitin-protein ligase CHIP(STUB1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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Mouse STUB1(E3 ubiquitin-protein ligase CHIP) ELISA Kit |
|||
| EM1381 | FN Test | 96T | EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
|||
Human STUB1/ E3 ubiquitin-protein ligase CHIP ELISA Kit |
|||
| E2420Hu | Sunlong | 1 Kit | EUR 685.2 |
Human STUB1(E3 ubiquitin-protein ligase CHIP) ELISA Kit |
|||
| EH3833 | FN Test | 96T | EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
|||
EpiQuik Tissue Methyl-Histone H3K27 ChIP Kit |
|||
| P-2016 | EpiGentek |
|
|
EpiNext ChIP-Seq High-Sensitivity Kit (Illumina) |
|||
| P-2030 | EpiGentek |
|
|
ELISA kit for Human STUB1 (E3 ubiquitin-protein ligase CHIP) |
|||
| E-EL-H5533 | Elabscience Biotech | 1 plate of 96 wells | EUR 640.8 |
|
Description: A sandwich ELISA kit for quantitative measurement of Human STUB1 (E3 ubiquitin-protein ligase CHIP) in samples from Serum, Plasma, Cell supernatant |
|||
ELISA kit for Human E3 ubiquitin-protein ligase CHIP (STUB1) |
|||
| KTE60397-48T | Abbkine | 48T | EUR 398.4 |
|
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|||
ELISA kit for Human E3 ubiquitin-protein ligase CHIP (STUB1) |
|||
| KTE60397-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2538 |
|
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|||
ELISA kit for Human E3 ubiquitin-protein ligase CHIP (STUB1) |
|||
| KTE60397-96T | Abbkine | 96T | EUR 646.8 |
|
Description: Quantitative sandwich ELISA for measuring Human E3 ubiquitin-protein ligase CHIP (STUB1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
|||
STUB1 ELISA Kit| Mouse E3 ubiquitin-protein ligase CHIP ELISA Ki |
|||
| EF013909 | Lifescience Market | 96 Tests | EUR 826.8 |
Rabbit IgG (non-immune, isotype control, CHIP/IP grade) |
|||
| 20009-1-CH | Alpha Diagnostics | 100 ug | EUR 270 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pG-Tn5) |
|||
| TD901-01 | Vazyme | 12 rxn | EUR 1195.2 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pG-Tn5) |
|||
| TD901-02 | Vazyme | 48 rxn | EUR 4153.2 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pA-Tn5) |
|||
| TD902-01 | Vazyme | 12 rxn | EUR 1195.2 |
Hyperactive In-Situ ChIP Library Prep Kit for Illumina (pA-Tn5) |
|||
| TD902-02 | Vazyme | 48 rxn | EUR 4153.2 |
MiniTurbo with 8-Well Sample Block (MiniTurbo Writer Programmable Chip and software included) |
|||
| MOL2706 | Scientific Laboratory Supplies | EACH | EUR 2160.77 |
Anti-CHIP antibody |
|||
| STJ192459 | St John's Laboratory | 200 µl | EUR 236.4 |
|
Description: Unconjugated Rabbit polyclonal to CHIP |
|||
pCMV-HA-chip Plasmid |
|||
| PVTB00025-2a | Lifescience Market | 2 ug | EUR 427.2 |
pcDNA3.0-Flag-CHIP Plasmid |
|||
| PVTB00152-2b | Lifescience Market | 2 ug | EUR 427.2 |
pcDNA3.0-EGFP-CHIP Plasmid |
|||
| PVTB00152-2c | Lifescience Market | 2 ug | EUR 427.2 |
pcDNA3.0-HA-CHIP Plasmid |
|||
| PVTB00152-2d | Lifescience Market | 2 ug | EUR 427.2 |
Human Chitinase 3 Like Protein 2 (CHI3L2) Protein |
|||
| 20-abx165963 | Abbexa |
|
|
CHI3L2 protein |
|||
| 80R-4391 | Fitzgerald | 50 ug | EUR 418.8 |
|
Description: Purified Recombinant CHI3L2 protein |
|||
Recombinant Human Chitinase-3-like protein 1/CHI3L1 Protein |
|||
| RP00521 | Abclonal | 10 μg | EUR 196.8 |
CHI3L1 protein (His tag) |
|||
| 80R-2666 | Fitzgerald | 10 ug | EUR 224.4 |
|
Description: Purified recombinant Human CHI3L1 protein (His tag) |
|||
Chicken C Reactive Protein (CRP) Protein |
|||
| 20-abx165887 | Abbexa |
|
|
CHI3L1 Recombinant Protein (Rat) |
|||
| RP194828 | ABM | 100 ug | Ask for price |
Chi3l3 Recombinant Protein (Rat) |
|||
| RP194831 | ABM | 100 ug | Ask for price |
Chicken IgG protein |
|||
| 31R-1070 | Fitzgerald | 10 mg | EUR 392.4 |
|
Description: Purified native Chicken IgG protein |
|||
Chicken IgY Protein |
|||
| abx060688-50mg | Abbexa | 50 mg | EUR 661.2 |
Chicken IgY Protein |
|||
| abx060689-10ml | Abbexa | 10 ml | EUR 594 |
Chicken IgY Protein |
|||
| abx061434-1g | Abbexa | 1 g | EUR 811.2 |
Chicken Heat Shock Protein Beta 2 (HSPb2) Protein |
|||
| 20-abx653692 | Abbexa |
|
|
CHI3L1 Recombinant Protein (Human) |
|||
| RP006988 | ABM | 100 ug | Ask for price |
CHI3L1 Recombinant Protein (Human) |
|||
| RP006991 | ABM | 100 ug | Ask for price |
CHI3L2 Recombinant Protein (Human) |
|||
| RP006994 | ABM | 100 ug | Ask for price |
CHI3L1 Recombinant Protein (Mouse) |
|||
| RP123905 | ABM | 100 ug | Ask for price |
Chi3l3 Recombinant Protein (Mouse) |
|||
| RP123908 | ABM | 100 ug | Ask for price |
Chi3l4 Recombinant Protein (Mouse) |
|||
| RP123911 | ABM | 100 ug | Ask for price |
HIV Chimeric Protein |
|||
| abx061422-1mg | Abbexa | 1 mg | EUR 844.8 |
HIV Chimeric Protein |
|||
| abx061423-1mg | Abbexa | 1 mg | EUR 844.8 |
HIV Chimeric Protein |
|||
| abx061425-1mg | Abbexa | 1 mg | EUR 844.8 |
HIV Chimeric Protein |
|||
| abx061426-1mg | Abbexa | 1 mg | EUR 844.8 |
Human Chitinase 1 (CHIT1) Protein |
|||
| 20-abx650761 | Abbexa |
|
|
Mouse Chitinase 1 (CHIT1) Protein |
|||
| 20-abx650762 | Abbexa |
|
|
Chicken Heat Shock 70kDa Protein 8 (HSPA8) Protein |
|||
| 20-abx067012 | Abbexa |
|
|
Chitinase 3-Like Protein 2 Recombinant Protein |
|||
| 91-523 | ProSci | 0.05 mg | EUR 651.3 |
|
Description: Chitinase 3-Like Protein 2 (CHI3L2) is a 39 kDa secreted glycoprotein which belongs to the glycosyl hydrolase 18 family and the most closely related to human cartilage glycoprotein 39, which promotes the growth of human synovial cells as well as skin and fetal lung fibroblasts. Highest expression of CHI3L2 is in chondrocytes, followed by synoviocytes, lung and heart. It is not detected in spleen, pancreas, and liver. CHI3L2 may also be expressed in developing brain and placenta. Increased levels of CHI3L2 have been demonstrated in synovial fluids of patients with rheumatoid or osteoarthritis as well as in some other pathologies and in malignant tumors, particularly in glioblastomas. CHI3L2 may bind glycan structure with high affinity, but not heparin. It has has no chitotriosidase activity, but is likely to bind some type of glycan. |
|||
Chicken Bone Morphogenetic Protein 4 (BMP4) Protein |
|||
| 20-abx065575 | Abbexa |
|
|
Chicken Bone Morphogenetic Protein 2 (BMP2) Protein |
|||
| 20-abx652679 | Abbexa |
|
|
Desmin protein (Chicken) |
|||
| 30R-AD003 | Fitzgerald | 250 ug | EUR 657.6 |
|
Description: Purified native Chicken Desmin protein |
|||
Chikungunya E2 Protein |
|||
| abx160009-1mg | Abbexa | 1 mg | EUR 1730.4 |
Chitinase-3-Like Protein 1 Recombinant Protein |
|||
| 91-408 | ProSci | 0.05 mg | EUR 556.8 |
|
Description: Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis. |
|||