Effects of Dietary Inclusion of Seaweed, Heat Stress and Genetic Strain on Performance, Plasma Biochemical and Hematological Parameters in Laying Hens
This study was planned to investigate the effects of seaweed supplementation, genetic strain, heat stress and their interactions on laying hen performances, blood chemistry and hematology. In a short-term trial, laying hens of the two genetic lines Lohman LSL-Lite (White) and Lohman Brown-Lite (Brown) were supplemented with Chondrus crispus (CC) at 3% for 21 days, while a control group was not.
In a long-term trial, the same two strains were assigned to control (0%), 3% red seaweed Chondrus crispus (CC) or 0.5% brown seaweed Ascophyllum nodosum (AN)-supplemented diets for 41 weeks, concluding with a four-week control or heat-stress period. The White hens displayed higher egg production and a lower feed/egg ratio. The short-term inclusion of CC significantly reduced the feed intake, weight gain and feed/egg ratio.
The long-term seaweed intake affected the plasma albumin and gamma-glutamyl transferase (GGT) (p < 0.05), and there were significant strain-heat stress interactions; heat stress in the Brown birds was associated with reduced protein, globulin and glucose and increased cholesterol and GGT levels and higher heterophil-to-lymphocyte (H/L) ratios (p < 0.05) in response to heat stress (p < 0.05).
In conclusion, a long-term seaweed supplementation affected the plasma protein and enzyme profiles, yet had little effect on hen leukocyte counts and the overall performance.
 ChromaFlash High-Sensitivity ChIP Kit |
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| P-2027 | EpiGentek | 48 Reactions | EUR 643.05 |
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Description: Ask the seller for details |
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 ChromaFlash Chromatin Extraction Kit |
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| P-2001 | EpiGentek | 100 Extractions | EUR 260.25 |
|
Description: The best epigenetics products |
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 ChromaFlash Plant Chromatin Extraction Kit |
|||
| P-2022 | EpiGentek | 50 Extractions | EUR 276.20 |
|
Description: reagents widely cited |
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 ChromaFlash Chromatin Isolation & Shearing Kit |
|||
| P-2023 | EpiGentek | 100 Preperations | EUR 270.40 |
|
Description: kits suitable for this type of research |
|||
 CHIP protein |
|||
| 30R-1245 | Fitzgerald | 100 ug | EUR 224.00 |
|
Description: Purified recombinant Human CHIP protein |
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CHIP protein |
|||
| 30R-2753 | Fitzgerald | 25 ug | EUR 425.00 |
|
Description: Purified recombinant Human CHIP protein |
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 EpiQuik Plant ChIP Kit |
|||
| P-2014 | EpiGentek | 48 Reactions | EUR 788.05 |
|
Description: Ask the seller for details |
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 Recombinant Human E3 Ubiquitin-Protein Ligase CHIP/CHIP |
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| C115-10ug | Novoprotein | 10ug | EUR 156.00 |
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Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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Recombinant Human E3 Ubiquitin-Protein Ligase CHIP/CHIP |
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| C115-1mg | Novoprotein | 1mg | EUR 2283.00 |
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Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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Recombinant Human E3 Ubiquitin-Protein Ligase CHIP/CHIP |
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| C115-500ug | Novoprotein | 500ug | EUR 1613.00 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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Recombinant Human E3 Ubiquitin-Protein Ligase CHIP/CHIP |
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| C115-50ug | Novoprotein | 50ug | EUR 369.00 |
|
Description: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
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 Kit) EpiQuik Chromatin Immunoprecipitation (ChIP) Kit |
|||
| P-2002 | EpiGentek | 96 Reactions | EUR 904.05 |
|
Description: Ask the seller for details |
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 Human CHIP Antibody |
|||
| 32585-05111 | AssayPro | 150 ug | EUR 261.00 |
 CHIP, human recombinant |
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| 4898-25 | Biovision | EUR 349.00 | |
 CHIP Polyclonal Antibody |
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| ABP58142-003ml | Abbkine | 0.03ml | EUR 158.00 |
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|
Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
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| ABP58142-01ml | Abbkine | 0.1ml | EUR 289.00 |
|
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|
Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
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| ABP58142-02ml | Abbkine | 0.2ml | EUR 414.00 |
|
|||
|
Description: A polyclonal antibody for detection of CHIP from Human, Mouse. This CHIP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human CHIP protein at amino acid sequence of 160-240 |
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CHIP Polyclonal Antibody |
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| ES11301-100ul | ELK Biotech | 100ul | EUR 279.00 |
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Description: A Rabbit Polyclonal antibody against CHIP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
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CHIP Polyclonal Antibody |
|||
| ES11301-50ul | ELK Biotech | 50ul | EUR 207.00 |
|
Description: A Rabbit Polyclonal antibody against CHIP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
|||
 Anti-CHIP antibody |
|||
| STJ192459 | St John's Laboratory | 200 µl | EUR 197.00 |
|
Description: Unconjugated Rabbit polyclonal to CHIP |
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 One Step RT PCR Kit |
|||
| 9K-005-0011 | BBI Biotech | 100Rxn, 100prep | EUR 267.50 |
|
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 One-Step RT-PCR Kit |
|||
| G174 | ABM | 100 x 50 ul reactions | EUR 233.00 |
 Pospiviroid One-Step PCR kit |
|||
| Oneq-A546-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Pospiviroid. |
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Pospiviroid One-Step PCR kit |
|||
| Oneq-A546-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Pospiviroid. |
|||
Pospiviroid One-Step PCR kit |
|||
| Oneq-A546-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Pospiviroid. |
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 Lactobacillus One-Step PCR kit |
|||
| Oneq-A566-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Lactobacillus. |
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Lactobacillus One-Step PCR kit |
|||
| Oneq-A566-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Lactobacillus. |
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Lactobacillus One-Step PCR kit |
|||
| Oneq-A566-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Lactobacillus. |
|||
 Lactococcus One-Step PCR kit |
|||
| Oneq-A567-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Lactococcus. |
|||
Lactococcus One-Step PCR kit |
|||
| Oneq-A567-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Lactococcus. |
|||
Lactococcus One-Step PCR kit |
|||
| Oneq-A567-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Lactococcus. |
|||
 Leuconostoc One-Step PCR kit |
|||
| Oneq-A569-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leuconostoc. |
|||
Leuconostoc One-Step PCR kit |
|||
| Oneq-A569-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leuconostoc. |
|||
Leuconostoc One-Step PCR kit |
|||
| Oneq-A569-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Leuconostoc. |
|||
 Pediococcus One-Step PCR kit |
|||
| Oneq-A571-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Pediococcus. |
|||
Pediococcus One-Step PCR kit |
|||
| Oneq-A571-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Pediococcus. |
|||
Pediococcus One-Step PCR kit |
|||
| Oneq-A571-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Pediococcus. |
|||
 Halobacillus One-Step PCR kit |
|||
| Oneq-A635-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Halobacillus. |
|||
Halobacillus One-Step PCR kit |
|||
| Oneq-A635-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Halobacillus. |
|||
Halobacillus One-Step PCR kit |
|||
| Oneq-A635-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Halobacillus. |
|||
 Enterovirus One-Step PCR kit |
|||
| Oneq-H433-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Enterovirus. |
|||
Enterovirus One-Step PCR kit |
|||
| Oneq-H433-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Enterovirus. |
|||
Enterovirus One-Step PCR kit |
|||
| Oneq-H433-50R | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Enterovirus. |
|||
 Mengovirus One-Step PCR kit |
|||
| Oneq-H453-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Mengovirus. |
|||
Mengovirus One-Step PCR kit |
|||
| Oneq-H453-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Mengovirus. |
|||
Mengovirus One-Step PCR kit |
|||
| Oneq-H453-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Mengovirus. |
|||
 Astrovirus One-Step PCR kit |
|||
| Oneq-H491-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Astrovirus. |
|||
Astrovirus One-Step PCR kit |
|||
| Oneq-H491-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Astrovirus. |
|||
Astrovirus One-Step PCR kit |
|||
| Oneq-H491-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Astrovirus. |
|||
 Calicivirus One-Step PCR kit |
|||
| Oneq-H493-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Calicivirus. |
|||
Calicivirus One-Step PCR kit |
|||
| Oneq-H493-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Calicivirus. |
|||
Calicivirus One-Step PCR kit |
|||
| Oneq-H493-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Calicivirus. |
|||
 Adenovirus One-Step PCR kit |
|||
| Oneq-H501-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Adenovirus. |
|||
Adenovirus One-Step PCR kit |
|||
| Oneq-H501-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Adenovirus. |
|||
Adenovirus One-Step PCR kit |
|||
| Oneq-H501-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Adenovirus. |
|||
 Polyomavirus One-Step PCR kit |
|||
| Oneq-H515-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Polyomavirus. |
|||
Polyomavirus One-Step PCR kit |
|||
| Oneq-H515-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Polyomavirus. |
|||
Polyomavirus One-Step PCR kit |
|||
| Oneq-H515-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Polyomavirus. |
|||
 Sapovirus One-Step PCR kit |
|||
| Oneq-H630-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Sapovirus. |
|||
Sapovirus One-Step PCR kit |
|||
| Oneq-H630-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Sapovirus. |
|||
Sapovirus One-Step PCR kit |
|||
| Oneq-H630-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Sapovirus. |
|||
 Parechovirus One-Step PCR kit |
|||
| Oneq-H642-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Parechovirus. |
|||
Parechovirus One-Step PCR kit |
|||
| Oneq-H642-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Parechovirus. |
|||
Parechovirus One-Step PCR kit |
|||
| Oneq-H642-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Parechovirus. |
|||
 Metapneumovirus One-Step PCR kit |
|||
| Oneq-H643-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Metapneumovirus. |
|||
Metapneumovirus One-Step PCR kit |
|||
| Oneq-H643-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Metapneumovirus. |
|||
Metapneumovirus One-Step PCR kit |
|||
| Oneq-H643-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Metapneumovirus. |
|||
 Entamoeba One-Step PCR kit |
|||
| Oneq-H683-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Entamoeba. |
|||
Entamoeba One-Step PCR kit |
|||
| Oneq-H683-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Entamoeba. |
|||
Entamoeba One-Step PCR kit |
|||
| Oneq-H683-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Entamoeba. |
|||
 Acanthamoeba One-Step PCR kit |
|||
| Oneq-H684-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Acanthamoeba . |
|||
Acanthamoeba One-Step PCR kit |
|||
| Oneq-H684-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Acanthamoeba . |
|||
Acanthamoeba One-Step PCR kit |
|||
| Oneq-H684-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Acanthamoeba . |
|||
 Echovirus One-Step PCR kit |
|||
| Oneq-H722-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Echovirus. |
|||
Echovirus One-Step PCR kit |
|||
| Oneq-H722-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Echovirus. |
|||
Echovirus One-Step PCR kit |
|||
| Oneq-H722-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Echovirus. |
|||
 ranavirus One-Step PCR kit |
|||
| Oneq-V337-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of ranavirus. |
|||
ranavirus One-Step PCR kit |
|||
| Oneq-V337-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of ranavirus. |
|||
ranavirus One-Step PCR kit |
|||
| Oneq-V337-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of ranavirus. |
|||
 Easy? One Step RT Kit |
|||
| M1162-100 | Biovision | EUR 468.00 | |
 Ruminococcus One-Step PCR kit |
|||
| Oneq-V619-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Ruminococcus. |
|||
Ruminococcus One-Step PCR kit |
|||
| Oneq-V619-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Ruminococcus. |
|||
Ruminococcus One-Step PCR kit |
|||
| Oneq-V619-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Ruminococcus. |
|||
 Bifidobacterium One-Step PCR kit |
|||
| Oneq-V621-100D | Bioingentech | 100T | EUR 747.40 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Bifidobacterium. |
|||
Bifidobacterium One-Step PCR kit |
|||
| Oneq-V621-150D | Bioingentech | 150T | EUR 838.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Bifidobacterium. |
|||
Bifidobacterium One-Step PCR kit |
|||
| Oneq-V621-50D | Bioingentech | 50T | EUR 628.50 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Bifidobacterium. |
|||
 Hantavirus One-Step PCR kit |
|||
| Oneq-VH373-100R | Bioingentech | 100T | EUR 933.00 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Hantavirus. |
|||
Hantavirus One-Step PCR kit |
|||
| Oneq-VH373-150R | Bioingentech | 150T | EUR 1060.60 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Hantavirus. |
|||
Hantavirus One-Step PCR kit |
|||
| Oneq-VH373-50R | Bioingentech | 50T | EUR 751.75 |
|
|||
|
Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Hantavirus. |
|||
A Soft Sensor Approach Based on an Echo State Network Optimized by Improved Genetic Algorithm
- In the process of fault diagnosis and the health and safety operation evaluation of modern industrial processes, it is crucial to measure important state variables, which cannot be directly detected due to limitations of economy, technology, environment and space.
- Therefore, this paper proposes a data-driven soft sensor approach based on an echo state network (ESN) optimized by an improved genetic algorithm (IGA). Firstly, with an ESN, a data-driven model (DDM) between secondary variables and dominant variables is established. Secondly, in order to improve the prediction performance, the IGA is utilized to optimize the parameters of the ESN.
- Then, the immigration strategy is introduced and the crossover and mutation operators are changed adaptively to improve the convergence speed of the algorithm and address the problem that the algorithm falls into the local optimum. Finally, a soft sensor model of an ESN optimized by an IGA is established (IGA-ESN), and the advantages and performance of the proposed method are verified by estimating the alumina concentration in an aluminum reduction cell.
- The experimental results illustrated that the proposed method is efficient, and the error was significantly reduced compared with the traditional algorithm.
Advances in Genetic Characterization and Genotype-Phenotype Correlation of Duchenne and Becker Muscular Dystrophy in the Personalized Medicine Era
Currently, Duchenne muscular dystrophy (DMD) and the related condition Becker muscular dystrophy (BMD) can be usually diagnosed using physical examination and genetic testing. While BMD features partially functional dystrophin protein due to in-frame mutations, DMD largely features no dystrophin production because of out-of-frame mutations. However, BMD can feature a range of phenotypes from mild to borderline DMD, indicating a complex genotype-phenotype relationship.
Despite two mutational hot spots in dystrophin, mutations can arise across the gene. The use of multiplex ligation amplification (MLPA) can easily assess the copy number of all exons, while next-generation sequencing (NGS) can uncover novel or confirm hard-to-detect mutations.
Exon-skipping therapy, which targets specific regions of the dystrophin gene based on a patient’s mutation, is an especially prominent example of personalized medicine for DMD. To maximize the benefit of exon-skipping therapies, accurate genetic diagnosis and characterization including genotype-phenotype correlation studies are becoming increasingly important.
In this article, we present the recent progress in the collection of mutational data and optimization of exon-skipping therapy for DMD/BMD
 Canine C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-c-96T | DL Develop | 96T | EUR 688.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Canine C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
|
Canine C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-c-48Tests | Reddot Biotech | 48 Tests | EUR 557.00 |
|
Canine C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-c-96Tests | Reddot Biotech | 96 Tests | EUR 774.00 |
|
Canine C-Peptide ELISA Kit |
|||
| RD-C-Peptide-c-48Tests | Reddot Biotech | 48 Tests | EUR 533.00 |
|
Canine C-Peptide ELISA Kit |
|||
| RD-C-Peptide-c-96Tests | Reddot Biotech | 96 Tests | EUR 740.00 |
 Human Apolipoprotein C-I protein control for WB |
|||
| APOC11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Apolipoprotein C-II protein control for WB |
|||
| APOC22-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Apolipoprotein C-III protein control for WB |
|||
| APOC32-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 control for WB) Purified Human C-Reactive Protein (CRP) control for WB |
|||
| CRP12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 control for WB) Purified Rat C-Reactive Protein (CRP) control for WB |
|||
| CRP16-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 control for WB) Purified Dog C-Reactive Protein (CRP) control for WB |
|||
| CRP18-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 C. perfringens beta toxin protein control for western blot) Recombinant (E.coli) C. perfringens beta toxin protein control for western blot |
|||
| CPB12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 C. perfringens epsilon toxin protein control for western blot) Recombinant (E.coli) C. perfringens epsilon toxin protein control for western blot |
|||
| CPE13-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 purified Mouse C-Reactive Protein (CRP) cotnrol for Western) Recombinant (NS0) purified Mouse C-Reactive Protein (CRP) cotnrol for Western |
|||
| CRP21-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
|
Recombinant (NS0) purified Mouse C-Reactive Protein (CRP) cotnrol for Western |
|||
| CRP24-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 C. perfringens alpha toxin protein control for western blot) Recombinant (E.coli) C. perfringens alpha toxin protein control for western blot |
|||
| CPA11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 control) Human recombinant purified His-tag c-myc protein (~65 kda) control |
|||
| MYC17-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 C-terminal (207-397 aa) His-tag protein control for Western Blot) Recombinant purified Circumsporozoite (CSP, P.falciparum) C-terminal (207-397 aa) His-tag protein control for Western Blot |
|||
| CSPF11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
) c-Myc Oncoprotein; Clone 9E10.3 (Concentrate) |
|||
| RA0226-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
c-Myc Oncoprotein; Clone 9E10.3 (Concentrate) |
|||
| RA0226-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
) c-Myc Oncoprotein; Clone MYC909 (Concentrate) |
|||
| RA0227-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
c-Myc Oncoprotein; Clone MYC909 (Concentrate) |
|||
| RA0227-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
; Clone 7H8.2C12 (Concentrate)) Cytochrome c (Mitochondrial Marker); Clone 7H8.2C12 (Concentrate) |
|||
| RA0359-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
Cytochrome c (Mitochondrial Marker); Clone 7H8.2C12 (Concentrate) |
|||
| RA0359-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
; Clone CTC05 (Concentrate)) Cytochrome c (Mitochondrial Marker); Clone CTC05 (Concentrate) |
|||
| RA0360-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
Cytochrome c (Mitochondrial Marker); Clone CTC05 (Concentrate) |
|||
| RA0360-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
 for ELISA/Western) Multi Fusion-Tagged recombinant Protein 52-Kda containing 16-tags (T-7, HSV, C-myc, VSV-G, Glu-Glu, V5, e-tag, Flag, S-tag, HA, KT3, E2, Au1, Au5, 6xHis-tags) for ELISA/Western |
|||
| MFPM52-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
; Clone T2H5 (Concentrate)) Tenascin C (Stromal Marker For Epithelial Malignancy); Clone T2H5 (Concentrate) |
|||
| RA0135-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
Tenascin C (Stromal Marker For Epithelial Malignancy); Clone T2H5 (Concentrate) |
|||
| RA0135-C.5 | ScyTek Laboratories | 0.5 ml | EUR 247.00 |
; Clone C-43 & DC10 (Concentrate)) Cytokeratin 8/18 (Epithelial Marker); Clone C-43 & DC10 (Concentrate) |
|||
| RA0388-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
Cytokeratin 8/18 (Epithelial Marker); Clone C-43 & DC10 (Concentrate) |
|||
| RA0388-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
) HER-2 / c-erbB-2 / neu / CD340; Clone HRB2/451 (Concentrate) |
|||
| RA0108-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
HER-2 / c-erbB-2 / neu / CD340; Clone HRB2/451 (Concentrate) |
|||
| RA0108-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
; Clone C117/370 (Concentrate)) CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors); Clone C117/370 (Concentrate) |
|||
| RA0168-C.1 | ScyTek Laboratories | 0.1 ml | EUR 125.00 |
|
CD117/c-Kit (Marker for Gastrointestinal Stromal Tumors); Clone C117/370 (Concentrate) |
|||
| RA0168-C.5 | ScyTek Laboratories | 0.5 ml | EUR 300.00 |
 Human C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-Hu-48T | DL Develop | 48T | EUR 398.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
|
Human C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-Hu-96T | DL Develop | 96T | EUR 511.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
 Mouse C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-Mu-48T | DL Develop | 48T | EUR 450.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
|
Mouse C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-Mu-96T | DL Develop | 96T | EUR 582.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Mouse C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
 Rat C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-Ra-48T | DL Develop | 48T | EUR 467.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
|
Rat C-Peptide ELISA Kit |
|||
| DLR-C-Peptide-Ra-96T | DL Develop | 96T | EUR 605.00 |
|
|||
|
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat C-Peptide in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
|||
|
Human C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 404.00 |
|
Human C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 556.00 |
|
Mouse C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 465.00 |
|
Mouse C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 643.00 |
|
Rat C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 486.00 |
|
Rat C-Peptide ELISA Kit |
|||
| RDR-C-Peptide-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 672.00 |
|
Human C-Peptide ELISA Kit |
|||
| RD-C-Peptide-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 387.00 |
|
Human C-Peptide ELISA Kit |
|||
| RD-C-Peptide-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 532.00 |
|
Mouse C-Peptide ELISA Kit |
|||
| RD-C-Peptide-Mu-48Tests | Reddot Biotech | 48 Tests | EUR 446.00 |
|
Mouse C-Peptide ELISA Kit |
|||
| RD-C-Peptide-Mu-96Tests | Reddot Biotech | 96 Tests | EUR 615.00 |
|
Rat C-Peptide ELISA Kit |
|||
| RD-C-Peptide-Ra-48Tests | Reddot Biotech | 48 Tests | EUR 465.00 |
|
Rat C-Peptide ELISA Kit |
|||
| RD-C-Peptide-Ra-96Tests | Reddot Biotech | 96 Tests | EUR 643.00 |
) DIRECTPCR LYSIS REAGENT (CELL) |
|||
| 302-C | Viagen | 100 ml | EUR 207.00 |
|
Description: For use with cultured cells |
|||
|
DIRECTPCR LYSIS REAGENT (CELL) |
|||
| 301-C | Viagen | 50 ml | EUR 141.00 |
|
Description: For use with cultured cells |
|||
 for ELISA Kit, 1 ml (target range ~20-30 ug/ml)) Monkey IgM (Rhesus, non-immune control) for ELISA Kit, 1 ml (target range ~20-30 ug/ml) |
|||
| 7060-C | Alpha Diagnostics | 1 ml | EUR 286.00 |
 Bovine DNAse 1 Protein Western blot +ve control |
|||
| DNASE11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 human DNAse I Protein control for WB) Recombinant (CHO) human DNAse I Protein control for WB |
|||
| DNASE12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
) Human spleen lysate protein control for Deoxyribonuclease II (Dnase II) |
|||
| DNASE23-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 for Western blot) DNP-labeled Molecular weight standard proteins (21, 29, 43, 68 , and 97 kda) for Western blot |
|||
| DNP45-C | Alpha Diagnostics | 1 set | EUR 286.00 |
 CHIKE26-R-10 |
|||
| APOA11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Apolipoprotein A-Il, Human Plasma protein control for WB |
|||
| APOA21-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Apolipoprotein B protein control for WB |
|||
| APOB21-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Recombinant Human ApoE protein W. Blot +ve control |
|||
| APOE11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
|
Recombinant Human ApoE protein W. Blot +ve control |
|||
| APOE12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human plasma Apolipoprotein E protein control for WB |
|||
| APOE13-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human ApoE3 protein W. Blot +ve control |
|||
| APOE31-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein control for WB) Recombinant purified Human ApoJ (Clusterin/Apolipoprotein J) protein control for WB |
|||
| APOJ11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Plasma Apolipoprotein J protein control for WB |
|||
| APOJ13-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein WB +ve control) Purified Recombinant Human Angiopoietin 1 (Ang-1) protein WB +ve control |
|||
| ANG12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Recombinant Human Angiopoietin 2 (Ang-2) WB +ve control) Purified (E.Coli) Recombinant Human Angiopoietin 2 (Ang-2) WB +ve control |
|||
| ANG27-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein control for WB) Mouse Angiopoietin 3 (Ang-3) protein control for WB |
|||
| ANG31-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein control for WB) Human Angiopoietin 4 (Ang-4) protein control for WB |
|||
| ANG41-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Recombinant purified Human Angiogenin protein W. blot +ve control |
|||
| ANGN12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Angiostatin Kringles 1-3 purified protein W. blot +ve positive control |
|||
| ANKR131-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein W. Blot +ve control) Purified Human Angiostatin (Kringles 1-4) protein W. Blot +ve control |
|||
| ANST12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 W. Blot +ve control) Human beta-2 glycoprotein (B2-GP or Apolipoprotein H/ApoH) W. Blot +ve control |
|||
| B2GP11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 WB +ve control) Purified Human beta-2 microglobulin (B2M) WB +ve control |
|||
| B2M11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 P30 protein control for western blot) Recombinant African Swine fever virus (ASFV) P30 protein control for western blot |
|||
| ASFV11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein control for WB) Purified, Porcine CABP9K (D9K/CALB3 or CABP1) protein control for WB |
|||
| D9K12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Domain protein (45 kda) control for Western) Recombinant Duffy Binding like5 (DBL5/VAR2CSA) Domain protein (45 kda) control for Western |
|||
| DBL51-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
) Control/Blocking peptide for Mouse Neuronal migration protein doublecortin (DCX) |
|||
| DCX11-C | Alpha Diagnostics | 100 ug | EUR 164.00 |
 control for western blot) Recombinant Classical Swine Fever Virus E2 protein (CSFV-E2) control for western blot |
|||
| CSFE21-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 control for western blot) Recombinant Classical Swine Fever Virus Erns protein (CSFV-Erns) control for western blot |
|||
| CSFR11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Circumsporozoite (P. vivax, CSP; 353-aa and GST) protein control for Western blot) Recombinant (E. coli) Circumsporozoite (P. vivax, CSP; 353-aa and GST) protein control for Western blot |
|||
| CSPV11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Liver Cathepsin B protein control for Western blot |
|||
| CTHB11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Liver Cathepsin D protein control for Western blot |
|||
| CTHD11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Recombinant purified mouse Liver Cathepsin D protein control for Western blot |
|||
| CTHD12-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Liver Cathepsin G protein control for Western blot |
|||
| CTHG11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Liver Cathepsin H protein control for Western blot |
|||
| CTHH11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Human Liver Cathepsin L protein control for Western blot |
|||
| CTHL11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 protein for Western blot) Recombinant purified Human Carboxyl Terminal Modulator Protein (CTMP) protein for Western blot |
|||
| CTMP11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Purified Cholera Toxin protein control for Western Blot |
|||
| CTOX11-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Purified Cholera Toxin A subunit protein control for Western Blot |
|||
| CTOX16-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
 Purified Cholera Toxin B subunit protein control for Western Blot |
|||
| CTOX27-C | Alpha Diagnostics | 100 ul | EUR 286.00 |
) Actin, Alpha-Smooth Muscle; Clone 1A4 (Concentrate) |
|||
| A00002-C | ScyTek Laboratories | 1 ml | EUR 497.00 |
) CD20, B-Cell; Clone L26 (Concentrate) |
|||
| A00003-C | ScyTek Laboratories | 1 ml | EUR 497.00 |
) Bcl-2; Clone 124 (Concentrate) |
|||
| A00004-C | ScyTek Laboratories | 1 ml | EUR 497.00 |
) Desmin; Clone D33 (Concentrate) |
|||
| A00007-C | ScyTek Laboratories | 1 ml | EUR 497.00 |
) Epithelial Membrane Antigen; Clone E29 (Concentrate) |
|||
| A00008-C | ScyTek Laboratories | 1 ml | EUR 497.00 |
) CD31, Endothelial Cell; Clone JC/70A (Concentrate) |
|||
| A00009-C | ScyTek Laboratories | 1 ml | EUR 497.00 |
) CD30, Ki-1 Antigen; Clone Ber-H2 (Concentrate) |
|||
| A00016-C | ScyTek Laboratories | 1 ml | EUR 497.00 |