Engineering multiple species-like genetic incompatibilities in insects
Speciation constrains the flow of genetic information between populations of sexually reproducing organisms. Gaining control over mechanisms of speciation would enable new strategies to manage wild populations of disease vectors, agricultural pests, and invasive species. Additionally, such control would provide safe biocontainment of transgenes and gene drives. Here, we demonstrate a general approach to create engineered genetic incompatibilities (EGIs) in the model insect Drosophila melanogaster.
EGI couples a dominant lethal transgene with a recessive resistance allele. Strains homozygous for both elements are fertile and fecund when they mate with similarly engineered strains, but incompatible with wild-type strains that lack resistant alleles. EGI genotypes can also be tuned to cause hybrid lethality at different developmental life-stages.
Further, we demonstrate that multiple orthogonal EGI strains of D. melanogaster can be engineered to be mutually incompatible with wild-type and with each other. EGI is a simple and robust approach in multiple sexually reproducing organisms.

CometAssay 96 Well ES Starter Kit plus EU Power Supply |
|||
4253-096-ESK-PS2 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus UK Power Supply |
|||
4253-096-ESK-PS3 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus SZ Power Supply |
|||
4253-096-ESK-PS4 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 20 Well ES Starter Kit plus AUS Power Supply |
|||
4252-040-ESK-PS5 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus AUS Power Supply |
|||
4253-096-ESK-PS5 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 20 Well ES Starter Kit plus Power Supply for UK |
|||
4252-040-ESK-PS3 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay Electrophoresis Starter Kit |
|||
4250-050-ESK | Biotechne | 1 Kit | EUR 3749.28 |
CometAssay Electrophoresis Starter Kit plus EU Power Supply |
|||
4250-050-ESK-PS2 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay Electrophoresis Starter Kit plus UK Power Supply |
|||
4250-050-ESK-PS3 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay Electrophoresis Starter Kit plus SZ Power Supply |
|||
4250-050-ESK-PS4 | Biotechne | 1 Kit | EUR 4597.68 |
Pipetman Starter Kit |
|||
F167300 | Scientific Laboratory Supplies | EACH | EUR 915.23 |
Mohs Lab Starter Kit |
|||
26417-1 | Polysciences Europe GmbH | 1kit | EUR 383 |
Pipetman L Starter Kit |
|||
F167350 | Scientific Laboratory Supplies | EACH | EUR 994.14 |
Pipetman G Starter Kit |
|||
F167900 | Scientific Laboratory Supplies | EACH | EUR 881.09 |
BMP21-LAB starter kit |
|||
LAB6029 | Scientific Laboratory Supplies | EACH | EUR 209.76 |
Triple-Pure Starter Kit |
|||
SLS1420 | Scientific Laboratory Supplies | PK50 | EUR 236.4 |
HOPE® Fixative Starter Kit |
|||
24884-1 | Polysciences Europe GmbH | 1kit | EUR 438 |
ELISA Starter Pack Kit |
|||
55R-E101PK | Fitzgerald | 1 kit | EUR 675.6 |
Description: ELISA reagent tool kit for use as a starter pack for researchers |
Axygen Axypet Pro Starter Kit |
|||
PIP2740 | Scientific Laboratory Supplies | EACH | EUR 1105.2 |
Thermal Test Film Starter Kit |
|||
PCR0892 | Scientific Laboratory Supplies | EACH | EUR 344.4 |
Lambda Plus Pipette Starter Kit |
|||
4069 | Scientific Laboratory Supplies | EACH | EUR 934.8 |
5mL MacroTube Starter Kit. Includes |
|||
C2500-SK | MTC Bio | 1/pack | EUR 220.38 |
Description: 5mL MacroTubes |
Cryo-EM Vitrification Starter Kit |
|||
M-CEM-VK301 | MiTeGen | 1 Kit | EUR 1371 |
Description: Cryo-EM Vitrification Starter Kit |
Multipette M4 dispenser starter kit |
|||
E4982000314 | Scientific Laboratory Supplies | EACH | EUR 450 |
Viability PCR Starter Kit with PMA |
|||
31075 | Biotium | 1kit | EUR 435.6 |
Description: Minimum order quantity: 1 unit of 1kit |
Storage Case for UniPuck Starter Kit |
|||
M-CP-UPSK-C1 | MiTeGen | 1 CASE | EUR 300 |
Description: Storage Case for UniPuck Starter Kit |
Viability PCR Starter Kit with PMAxxâ„¢ |
|||
31075-X | Biotium | 1kit | EUR 435.6 |
Description: Minimum order quantity: 1 unit of 1kit |
Kinesis Siltite Thermo MS Starter Kit |
|||
CHR1936 | Scientific Laboratory Supplies | EACH | EUR 378 |
Cryo-EM Puck Starter Kit Storage Case |
|||
M-CEMG2-SC1 | MiTeGen | 1 CASE | EUR 300 |
Description: Cryo-EM Puck Starter Kit Storage Case |
UVT/UVH RPL. STARTER |
|||
IB46560 | IBI Scientific | - | EUR 26.27 |
Corning Lambda EliteTouch Pipette Starter Kit |
|||
6065 | Scientific Laboratory Supplies | PK25 | EUR 1183.2 |
IsoTherm-System Starter |
|||
E3880001018 | Scientific Laboratory Supplies | EACH | EUR 184.8 |
Mohs Lab Starter Kit with Diagnostic Stains |
|||
26418-1 | Polysciences Europe GmbH | 1kit | EUR 916 |
Spine Puck Starter Kit Protective Storage Case |
|||
M-SPSK-Case | MiTeGen | 1 CASE | EUR 300 |
Description: Spine Puck Starter Kit Protective Storage Case |
Large tissue Starter box |
|||
HOM1090 | Scientific Laboratory Supplies | PK50 | EUR 320.4 |
Protein Crystallization Starter Kit, English Version |
|||
M-CS-401EN | MiTeGen | 1 Kit | EUR 156 |
Description: Protein Crystallization Starter Kit, English Version |
Kinesis Siltite Ferrule Starter Kit 0.25mm Column |
|||
CHR1893 | Scientific Laboratory Supplies | PK10 | EUR 148.8 |
Kinesis Siltite Ferrule Starter Kit 0.32mm column |
|||
CHR1894 | Scientific Laboratory Supplies | PK10 | EUR 140.4 |
Kinesis Siltite Ferrule Starter Kit 0.53mm column |
|||
CHR1895 | Scientific Laboratory Supplies | PK10 | EUR 140.4 |
BRAND Transferpette S Starter-Kit Midi |
|||
PIP5230 | Scientific Laboratory Supplies | EACH | EUR 968.4 |
Eppendorf 5ml Starter Pack |
|||
E0030119380 | Scientific Laboratory Supplies | EACH | EUR 166.8 |
Neurons Starter Kit (iPSC from Blood Cells; Male) |
|||
ASE-9321K | Applied StemCell | 1 Kit | EUR 473.1 |
Description: 12 month |
BRAND Transferpette S Starter-Kit Micro |
|||
PIP5229 | Scientific Laboratory Supplies | EACH | EUR 974.4 |
BRAND Transferpette S Starter-Kit Macro |
|||
PIP5232 | Scientific Laboratory Supplies | EACH | EUR 974.4 |
Viability PCR Starter Kit with PMA and Enhancer |
|||
31076 | Biotium | 1kit | EUR 435.6 |
Description: Minimum order quantity: 1 unit of 1kit |
starter uv tube 4w-20w |
|||
VLST151 | Consort | ea | EUR 67.2 |
Neurons Starter Kit (iPSC from Blood Cells; Female) |
|||
ASE-9321KF | Applied StemCell | 1 Kit | EUR 473.1 |
Description: 12 month |
BRAND Transferpette S Starter-Kit Standard |
|||
PIP5231 | Scientific Laboratory Supplies | EACH | EUR 972 |
Viability PCR Starter Kit with PMAxxâ„¢ and Enhancer |
|||
31076-X | Biotium | 1kit | EUR 435.6 |
Description: Minimum order quantity: 1 unit of 1kit |
Kinesis upchurch HPLC Starter Fittings Kit |
|||
CHR2409 | Scientific Laboratory Supplies | EACH | EUR 334.23 |
Starter Pack Repeater Syringes |
|||
6636 | Scientific Laboratory Supplies | EACH | EUR 553.2 |
Lambda EliteTouch Starter Pack |
|||
PIP0382 | Scientific Laboratory Supplies | EACH | EUR 1050 |
Kinesis SILTITE FINGERTITE VARIAN INJ/MS STARTER KIT |
|||
CHR1938 | Scientific Laboratory Supplies | EACH | EUR 378 |
Kinesis SILTITE FINGERTITE VARIAN INJ / FID STARTER KIT |
|||
CHR1937 | Scientific Laboratory Supplies | EACH | EUR 378 |
BioMag®Plus Streptavidin / Biotin Binding Starter Kit |
|||
86030-1 | Polysciences Europe GmbH | 1kit | EUR 624 |
XT STARTER PCR96 KIT, CONTAINS XT STARTER OPEN PLATFORM ICE-FREE BENCHTOP COOLER AND COOLRACK PCR MODULE |
|||
432016 | CORNING | 1/pk | EUR 622.8 |
Description: BioCision; BioCision CoolBox |
Kinesis Siltite Fingertite Inj/MS Starter Kit compatible with Agilent GC |
|||
CHR1935 | Scientific Laboratory Supplies | EACH | EUR 378 |
Gilson TRACKMAN PIPETMAN M Bt Connected Starter Kit Pro |
|||
FB10221 | Scientific Laboratory Supplies | EACH | EUR 4501.2 |
BioMag®Plus Protein A - Antibody Isolation Starter Kit |
|||
86040-1 | Polysciences Europe GmbH | 1kit | EUR 624 |
BioMag®Plus Protein G - Antibody Isolation Starter Kit |
|||
86050-1 | Polysciences Europe GmbH | 1kit | EUR 624 |
Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Male) |
|||
ASE-9323K | Applied StemCell | 1 vial | EUR 546 |
Description: 12 month |
XT STARTER M-PCR KIT, CONTAINS XT STARTER OPEN PLATFORM ICE-FREE BENCHTOP COOLER AND COOLRACK M-PCR MODULE |
|||
432017 | CORNING | 1/pk | EUR 613.2 |
Description: BioCision; BioCision CoolBox |
Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Male) |
|||
ASE-9322PK | Applied StemCell | 1 Kit | EUR 497.4 |
Description: 12 month |
Corning XT Starter Kit complete - low profile open platform Ice-free Cooler |
|||
432014 | Scientific Laboratory Supplies | 1KIT | EUR 274.8 |
Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Female) |
|||
ASE-9323KF | Applied StemCell | 1 vial | EUR 546 |
Description: 12 month |
Triple-Pure Starter Kit, 10 each of 0.1, 0.5, 1.0, 1.5 and 3.0mm |
|||
BCM1202 | Bio Basic | 1 pcs, 1 UNIT | EUR 292.37 |
Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Female) |
|||
ASE-9322PKF | Applied StemCell | 1 Kit | EUR 497.4 |
Description: 12 month |
Starter Kit 100 Maxitips 10 dispensing parts 10 valves 2 Maxitips G |
|||
E0030050525 | Scientific Laboratory Supplies | PK102 | EUR 99.6 |
Gilson TRACKMAN PIPETMAN M Bt Connected Multi Channel Starter Kit |
|||
FB10211 | Scientific Laboratory Supplies | EACH | EUR 4449.6 |
Multiple Head Starter Set for Genie 2 |
|||
MIX5002 | Scientific Laboratory Supplies | EACH | EUR 195.6 |
Gilson TRACKMAN PIPETMAN M Bt Connected Single Channel Starter Kit |
|||
FB10201 | Scientific Laboratory Supplies | EACH | EUR 3417.6 |
Immunoprecipitation Starter Pack 2 x 2mL |
|||
17600235 | Scientific Laboratory Supplies | EACH | EUR 757.2 |
Prefilled - Triple-Pure Starter Kit, 10 each of 0.1, 0.5, 1.0, 1.5 and 3.0mm |
|||
D1032-SK | Benchmark Scientific | 1 PC | EUR 178.4 |
Distel Dosing System Starter Pack 6x1 Litre |
|||
CLE1144 | Scientific Laboratory Supplies | EACH | EUR 164.4 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203APEAQUSP | Scientific Laboratory Supplies | EACH | EUR 492 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203APEORGSP | Scientific Laboratory Supplies | EACH | EUR 492 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203NPEAQUSP | Scientific Laboratory Supplies | EACH | EUR 471.6 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203NPENYLSP | Scientific Laboratory Supplies | EACH | EUR 469.2 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203NPEORGSP | Scientific Laboratory Supplies | EACH | EUR 471.6 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203NPEPPSP | Scientific Laboratory Supplies | EACH | EUR 469.2 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203NPUAQUSP | Scientific Laboratory Supplies | EACH | EUR 471.6 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGN203NPUORGSP | Scientific Laboratory Supplies | EACH | EUR 471.6 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGS203NPEORGSP | Scientific Laboratory Supplies | EACH | EUR 484.8 |
WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P |
|||
WHAGS203NPUORGSP | Scientific Laboratory Supplies | EACH | EUR 484.8 |
Precellys 2mL Lysing Kits - Soft tissue Starter box |
|||
HOM1060 | Scientific Laboratory Supplies | PK40 | EUR 238.8 |
Finntip 10 0.2-10ul Pink refill starter kit - 4 x 192 rack plus 10 x 192 refill |
|||
PIP3646 | Scientific Laboratory Supplies | EACH | EUR 274.8 |
AXYGEN® AXYPET® PRO STARTER KIT: 4 PIPETTORS, PLEXI STAND, SAMPLE TIPS |
|||
AP-STR-KIT-P | CORNING | 1/pk | EUR 865.2 |
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
BioMag®Plus Goat anti-Mouse IgG Particle Antibody Coupling Starter Kit |
|||
86020-1 | Polysciences Europe GmbH | 1kit | EUR 624 |
Finntip Flex 1000 50-1000ul Blue Refill starter kit 1 x 96 rack + 16 x 96 rack |
|||
PIP3696 | Scientific Laboratory Supplies | EACH | EUR 199.2 |
hybex Media Storage Bottle Starter Pack Blue Cap |
|||
BOT1866 | Scientific Laboratory Supplies | EACH | EUR 223.26 |
Precellys 2mL Lysing Kits - Micro-organism Starter box |
|||
HOM1062 | Scientific Laboratory Supplies | PK40 | EUR 238.8 |
NextPette Starter Pack 0.5-10 2-20 20-200 100-1000 |
|||
PIP1351 | Scientific Laboratory Supplies | EACH | EUR 787.2 |
NextPette Starter Pack 20-200 100-1000 1-5 1-10 |
|||
PIP1352 | Scientific Laboratory Supplies | EACH | EUR 818.4 |
hybex Media Storage Bottle Starter Pack Green Cap |
|||
BOT1874 | Scientific Laboratory Supplies | EACH | EUR 223.26 |
hybex Media Storage Bottle Starter Pack White Cap |
|||
BOT1890 | Scientific Laboratory Supplies | EACH | EUR 223.26 |
hybex Media Storage Bottle Starter Pack Purple Cap |
|||
BOT1882 | Scientific Laboratory Supplies | EACH | EUR 223.26 |
hybex Media Storage Bottle Starter Pack Yellow Cap |
|||
BOT1898 | Scientific Laboratory Supplies | EACH | EUR 223.26 |
Finntip Flex 10 0.1-10ul Pink Refill starter kit 1 x 96 rack + 20 x 96 refills |
|||
PIP3652 | Scientific Laboratory Supplies | EACH | EUR 219.6 |
myGel Mini Electrophoresis System Starter Kit (Includes E1101, A1701 and W4000-100) |
|||
E1101-SK | Benchmark Scientific | 1 each | EUR 712.8 |
Finntip Flex 200 5-200ul Yellow Refill starter kit 1 x 96 rack + 20 x 96 refill |
|||
PIP3664 | Scientific Laboratory Supplies | EACH | EUR 219.6 |
Finntip Flex 300 5-300ul Orange Refill starter kit 1 x 96 rack + 20 x 96 refill |
|||
PIP3682 | Scientific Laboratory Supplies | EACH | EUR 219.6 |
Eppendorf PCR Cooler 0.2 ml Starter 1x pink 1x blue |
|||
E3881000015 | Scientific Laboratory Supplies | EACH | EUR 123.6 |
hybex Media Storage Bottle Starter Pack Assorted Caps |
|||
BOT1906 | Scientific Laboratory Supplies | EACH | EUR 223.26 |
XT Starter holder only open platform ice free cooler |
|||
432015 | Scientific Laboratory Supplies | EACH | EUR 86.4 |
Finntip Flex 1200 50-1200ul Turquoise Refill starter kit 1 x 96 rack + 16 x 96 refill |
|||
PIP3704 | Scientific Laboratory Supplies | EACH | EUR 355.2 |
myGel Mini Electrophoresis System Starter Kit (Includes E1101-E, A1701 and W4000-100) |
|||
E1101-SK-E | Benchmark Scientific | 1 PC | EUR 742.5 |
Eppendorf UVette DNA RNAse And Protease Free Starter Set |
|||
E4099100007 | Scientific Laboratory Supplies | EACH | EUR 106.8 |
IsoTherm-System Starter Set for micro test tubes 0.5 ml |
|||
E3880000011 | Scientific Laboratory Supplies | EACH | EUR 184.8 |
AXYPET STARTER KIT 1 AP-20, AP-200 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS |
|||
AP-STR-KIT-1 | CORNING | 1/pk | EUR 426 |
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
AXYPET STARTER KIT 2 AP-10, AP-100 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS |
|||
AP-STR-KIT-2 | CORNING | 1/pk | EUR 440.4 |
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
Corning DWorks 1-200uL Pipet Tips Reload Starter Kit Nonsterile 96tip/Deck 10 Decks/Pack 960tip/Pack |
|||
4132 | Scientific Laboratory Supplies | PK960 | EUR 85.2 |
Eppendorf Conical Tubes 25mL with snap cap Starter Pack PCR clean |
|||
E0030118502 | Scientific Laboratory Supplies | EACH | EUR 120 |
Eppendorf Conical Tubes 25mL with screw cap Starter Pack PCR clean |
|||
E0030122500 | Scientific Laboratory Supplies | EACH | EUR 123.6 |
Corning 3D Clear Starter Kit - Includes Reagent/Antibody Buffer/Blocking Buffer/Penetration Buffer/Washing Buffers |
|||
5730 | Scientific Laboratory Supplies | EACH | EUR 955.2 |
BeadBug(TM) prefilled tubes; 2.0 mL capacity; Triple-Pure starter kit; with 10 each of 0.1; 0.5; 1.0; 1.5 and 3.0 mm Zirconium beads |
|||
Z763810-1KT | Scientific Laboratory Supplies | PK50 | EUR 177.6 |
hybex™ Media storage bottle, STARTER PACK (GL45) blue cap (Includes 2x100ml, 3x250ml, 3x500ml and 2x1000ml) |
|||
B3000-SP-B | Benchmark Scientific | 1 each | EUR 146.7 |
Aberrant Early Growth of Individual Trigeminal Sensory and Motor Axons in a Series of Mouse Genetic Models of 22q11.2 Deletion Syndrome
- We identified divergent modes of initial axon growth that prefigure disrupted differentiation of the trigeminal nerve (CN V), a cranial nerve essential for suckling, feeding and swallowing (S/F/S), a key innate behavior compromised in multiple genetic developmental disorders including DiGeorge/22q11.2 Deletion Syndrome (22q11.2 DS). We combined rapid in vivo labeling of single CN V axons in LgDel+/- mouse embryos, a genomically accurate 22q11.2DS model, and 3-dimensional imaging to identify and quantify phenotypes that could not be resolved using existing methods.
- We assessed these phenotypes in three 22q11.2-related genotypes to determine whether individual CN V motor and sensory axons wander, branch and sprout aberrantly in register with altered anterior-posterior hindbrain patterning and gross morphological disruption of CN V seen in LgDel+/-. In the additional 22q11.2-related genotypes: Tbx1+/-, Ranbp1-/-, Ranbp1+/-, and LgDel+/-:Raldh2+/-; axon phenotypes are seen when hindbrain patterning and CN V gross morphology is altered, but not when it is normal or restored toward WT.
- This disordered growth of CN V sensory and motor axons, whose appropriate targeting is critical for optimal S/F/S, may be an early, critical determinant of imprecise innervation leading to inefficient oropharyngeal function associated with 22q11.2 deletion from birth onward.
A Faster and More Accurate Algorithm for Calculating Population Genetics Statistics Requiring Sums of Stirling Numbers of the First Kind
Ewen’s sampling formula is a foundational theoretical result that connects probability and number theory with molecular genetics and molecular evolution; it was the analytical result required for testing the neutral theory of evolution, and has since been directly or indirectly utilized in a number of population genetics statistics.
Ewen’s sampling formula, in turn, is deeply connected to Stirling numbers of the first kind. Here, we explore the cumulative distribution function of these Stirling numbers, which enables a single direct estimate of the sum, using representations in terms of the incomplete beta function.
This estimator enables an improved method for calculating an asymptotic estimate for one useful statistic, Fu’s Fs By reducing the calculation from a sum of terms involving Stirling numbers to a single estimate, we simultaneously improve accuracy and dramatically increase speed
Quantitative genetic architecture of adaptive phenology traits in the deciduous tree, Populus trichocarpa (Torr. and Gray)
In a warming climate, the ability to accurately predict and track shifting environmental conditions will be fundamental for plant survival. Environmental cues define the transitions between growth and dormancy as plants synchronise development with favourable environmental conditions, however these cues are predicted to change under future climate projections which may have profound impacts on tree survival and growth.
Here, we use a quantitative genetic approach to estimate the genetic basis of spring and autumn phenology in Populus trichocarpa to determine this species capacity for climate adaptation. We measured bud burst, leaf coloration, and leaf senescence traits across two years (2017-2018) and combine these observations with measures of lifetime growth to determine how genetic correlations between phenology and growth may facilitate or constrain adaptation. Timing of transitions differed between years, although we found strong cross year genetic correlations in all traits, suggesting that genotypes respond in consistent ways to seasonal cues.
Spring and autumn phenology were correlated with lifetime growth, where genotypes that burst leaves early and shed them late had the highest lifetime growth. We also identified substantial heritable variation in the timing of all phenological transitions (h2 = 0.5-0.8) and in lifetime growth (h2 = 0.8).
The combination of additive variation and favourable genetic correlations in phenology traits suggests that populations of cultivated varieties of P. Trichocarpa may have the capability to adapt their phenology to climatic changes without negative impacts on growth
OxiSelect Comet Assay Kit (3-Well Slides) |
|||
STA-351-5 | Cell Biolabs | 5 x 75 assays | EUR 2836.8 |
Description: Our OxiSelect 3-Well Comet Assay Kits provide a fast, convenient way to screen for general DNA damage, regardless of the source or nature of the damage. Kits include Comet Slides, reagents, and a fluorescent dye to visualize cells under an epifluorescence microscope. |
CometAssay Electrophoresis Starter Kit |
|||
4250-050-ESK | Biotechne | 1 Kit | EUR 3749.28 |
CometAssay 20 Well ES Starter Kit plus NA Power Supply |
|||
4252-040-ESK-PS1 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 20 Well ES Starter Kit plus EU Power Supply |
|||
4252-040-ESK-PS2 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 20 Well ES Starter Kit plus SZ Power Supply |
|||
4252-040-ESK-PS4 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus NA Power Supply |
|||
4253-096-ESK-PS1 | Biotechne | 1 Kit | EUR 4528.8 |
CometAssay 96 Well ES Starter Kit plus EU Power Supply |
|||
4253-096-ESK-PS2 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus UK Power Supply |
|||
4253-096-ESK-PS3 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus SZ Power Supply |
|||
4253-096-ESK-PS4 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 20 Well ES Starter Kit plus AUS Power Supply |
|||
4252-040-ESK-PS5 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 96 Well ES Starter Kit plus AUS Power Supply |
|||
4253-096-ESK-PS5 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay 20 Well ES Starter Kit plus Power Supply for UK |
|||
4252-040-ESK-PS3 | Biotechne | 1 Kit | EUR 4597.68 |
CometSlide |
|||
4250-200-03 | Biotechne | 100 slides | EUR 520.32 |
CometAssay 96 |
|||
4253-096-K | Biotechne | 96 tests | EUR 513.6 |
Cometslides |
|||
4250-004-03 | Biotechne | 2 Tests | EUR 150.72 |
Cometslides |
|||
4250-050-03 | Biotechne | 25 Each | EUR 256.56 |
CometAssay HT Slide |
|||
4252-040-01 | Biotechne | 2 Tests | EUR 170.88 |
CometAssay HT Slide |
|||
4252-200-01 | Biotechne | 10 Tests | EUR 436.32 |
CometAssay HT Slide |
|||
4252-500-01 | Biotechne | 25 Tests | EUR 684.96 |
CometAssay Electrophoresis Starter Kit plus EU Power Supply |
|||
4250-050-ESK-PS2 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay Electrophoresis Starter Kit plus UK Power Supply |
|||
4250-050-ESK-PS3 | Biotechne | 1 Kit | EUR 4597.68 |
CometAssay Electrophoresis Starter Kit plus SZ Power Supply |
|||
4250-050-ESK-PS4 | Biotechne | 1 Kit | EUR 4597.68 |
96-Well CometSlides |
|||
4253-096-03 | Biotechne | 1 Tests | EUR 170.88 |
CometAssay LMAgarose |
|||
4250-050-02 | Biotechne | 15 mL | EUR 165.84 |
CometAssay LMAgarose |
|||
4250-500-02 | Biotechne | 100 mL | EUR 562.32 |
Cometslides Rack System |
|||
4252-040-02 | Biotechne | 1 Each | EUR 256.56 |
CometAssay Lysis Solution |
|||
4250-010-01 | Biotechne | 100 mL | EUR 189.36 |
CometAssay Lysis Solution (2 x 500 mL) |
|||
4250-050-01 | Biotechne | 1 L | EUR 219.6 |
OxiSelect Comet Assay Slides (3-Well) |
|||
STA-352 | Cell Biolabs | 5 slides | EUR 261.6 |
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy. |
OxiSelect Comet Assay Slides (3-Well) |
|||
STA-353 | Cell Biolabs | 25 slides | EUR 435.6 |
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy. |
OxiSelect Comet Assay Slides (3-Well) |
|||
STA-353-5 | Cell Biolabs | 5 x 25 slides | EUR 1521.6 |
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy. |
OxiSelect 96-Well Comet Assay Slide |
|||
STA-356 | Cell Biolabs | 1 slide | EUR 219.6 |
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy. |
OxiSelect 96-Well Comet Assay Slide |
|||
STA-356-5 | Cell Biolabs | 5 slides | EUR 622.8 |
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy. |
OxiSelect Comet Assay Control Cells |
|||
STA-354 | Cell Biolabs | 1 set | EUR 303.6 |
Description: OxiSelect Comet Assay Control Cells are a set of two cell lines that serve as a positive control (Etoposide-treated) and a negative control (untreated) respectively. |
CometAssay High Throughput Slides |
|||
4252-02K-01 | Biotechne | 100 tests | EUR 1943.28 |
CometAssay Neutral Control Slides |
|||
4257-010-NC | Biotechne | 10 Tests | EUR 389.28 |
CometAssay Alkaline Control Slides |
|||
4256-010-CC | Biotechne | 10 Tests | EUR 389.28 |
CometAssay Electrophoresis System |
|||
4250-050-ES | Biotechne | 1 Kit | EUR 3540.96 |
CometAssay Single Cell Gel Electrophoresis Assay |
|||
4250-050-K | Biotechne | 50 tests | EUR 513.6 |
CometAssay Single Cell Gel Electrophoresis Assay-Silver |
|||
4251-050-K | Biotechne | 1 kit | EUR 684.96 |
COMPtrol Kit |
|||
CMIGP-08-2K | Spherotech | 1x2 mL (fluorescent) | EUR 327.6 |
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone. |
C3 ELISA Kit| Rat Complement Component 3 ELISA Kit |
|||
EF016915 | Lifescience Market | 96 Tests | EUR 826.8 |
C4 ELISA Kit| Rat Complement Component 4 ELISA Kit |
|||
EF016949 | Lifescience Market | 96 Tests | EUR 826.8 |
C6 ELISA Kit| Rat Complement component C6 ELISA Kit |
|||
EF018502 | Lifescience Market | 96 Tests | EUR 826.8 |
C5 ELISA Kit| Rat Complement Component 5 ELISA Kit |
|||
EF017579 | Lifescience Market | 96 Tests | EUR 826.8 |
C9 ELISA Kit| Rat Complement Component 9 ELISA Kit |
|||
EF017581 | Lifescience Market | 96 Tests | EUR 826.8 |
C3a ELISA Kit| Rat Complement Component 3a ELISA Kit |
|||
EF016916 | Lifescience Market | 96 Tests | EUR 826.8 |
C4a ELISA Kit| Rat Complement Component 4a ELISA Kit |
|||
EF016950 | Lifescience Market | 96 Tests | EUR 826.8 |
C5a ELISA Kit| Rat Complement Component 5a ELISA Kit |
|||
EF017580 | Lifescience Market | 96 Tests | EUR 826.8 |
C4 ELISA Kit| Mouse Complement Component 4 ELISA Kit |
|||
EF012783 | Lifescience Market | 96 Tests | EUR 826.8 |
C9 ELISA Kit| Mouse Complement component C9 ELISA Kit |
|||
EF014543 | Lifescience Market | 96 Tests | EUR 826.8 |
Comt/ Rat Comt ELISA Kit |
|||
ELI-46977r | Lifescience Market | 96 Tests | EUR 1063.2 |
COMP/ Rat COMP ELISA Kit |
|||
ELA-E1197r | Lifescience Market | 96 Tests | EUR 1063.2 |
Comp/ Rat Comp ELISA Kit |
|||
ELI-03952r | Lifescience Market | 96 Tests | EUR 1063.2 |
C3 ELISA Kit| Monkey Complement Component 3 ELISA Kit |
|||
EF012684 | Lifescience Market | 96 Tests | EUR 826.8 |
C4 ELISA Kit| Monkey Complement Component 4 ELISA Kit |
|||
EF012685 | Lifescience Market | 96 Tests | EUR 826.8 |
C3a ELISA Kit| Mouse Complement Component 3a ELISA Kit |
|||
EF012782 | Lifescience Market | 96 Tests | EUR 826.8 |
C4a ELISA Kit| Mouse Complement Component 4a ELISA Kit |
|||
EF013475 | Lifescience Market | 96 Tests | EUR 826.8 |
C5a ELISA Kit| Mouse Complement Component 5a ELISA Kit |
|||
EF013476 | Lifescience Market | 96 Tests | EUR 826.8 |
C6 ELISA Kit| Bovine Complement component C6 ELISA Kit |
|||
EF011249 | Lifescience Market | 96 Tests | EUR 826.8 |
C9 ELISA Kit| Bovine Complement component C9 ELISA Kit |
|||
EF011250 | Lifescience Market | 96 Tests | EUR 826.8 |
C3a ELISA Kit| Sheep Complement Component 3a ELISA Kit |
|||
EF019499 | Lifescience Market | 96 Tests | EUR 826.8 |
C5a ELISA Kit| Monkey Complement Component 5a ELISA Kit |
|||
EF012686 | Lifescience Market | 96 Tests | EUR 826.8 |
C3 ELISA Kit| Porcine Complement Component 3 ELISA Kit |
|||
EF016572 | Lifescience Market | 96 Tests | EUR 826.8 |
C3a ELISA Kit| Rabbit Complement Component 3a ELISA Kit |
|||
EF016782 | Lifescience Market | 96 Tests | EUR 826.8 |
C5a ELISA Kit| Rabbit Complement Component 5a ELISA Kit |
|||
EF016783 | Lifescience Market | 96 Tests | EUR 826.8 |
C3a ELISA Kit| Porcine Complement Component 3a ELISA Kit |
|||
EF016573 | Lifescience Market | 96 Tests | EUR 826.8 |
C5a ELISA Kit| Porcine Complement Component 5a ELISA Kit |
|||
EF016574 | Lifescience Market | 96 Tests | EUR 826.8 |
Commd5/ Rat Commd5 ELISA Kit |
|||
ELI-50340r | Lifescience Market | 96 Tests | EUR 1063.2 |
Commd3/ Rat Commd3 ELISA Kit |
|||
ELI-50778r | Lifescience Market | 96 Tests | EUR 1063.2 |
C3 ELISA Kit| Guinea pig Complement Component 3 ELISA Kit |
|||
EF012601 | Lifescience Market | 96 Tests | EUR 826.8 |
Cd93 ELISA Kit| Rat Complement component C1q receptor ELISA Kit |
|||
EF018448 | Lifescience Market | 96 Tests | EUR 826.8 |
C8b ELISA Kit| Rat Complement component C8 beta chain ELISA Kit |
|||
EF018503 | Lifescience Market | 96 Tests | EUR 826.8 |
Rat COMT ELISA Kit |
|||
ERC0052 | Abclonal | 96Tests | EUR 625.2 |
Rat COMP ELISA Kit |
|||
ERC0212 | Abclonal | 96Tests | EUR 625.2 |
Rat COMP ELISA Kit |
|||
STJ150493 | St John's Laboratory | 1 kit | EUR 494.4 |
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of COMP in Rat serum, plasma and other biological fluids |
Goat COMT ELISA Kit |
|||
EGTC0052 | Abclonal | 96Tests | EUR 625.2 |
Goat COMP ELISA Kit |
|||
EGTC0212 | Abclonal | 96Tests | EUR 625.2 |
C3 ELISA Kit| Mouse Complement C3 ELISA Kit |
|||
EF012781 | Lifescience Market | 96 Tests | EUR 826.8 |
C5 ELISA Kit| Mouse Complement C5 ELISA Kit |
|||
EF013316 | Lifescience Market | 96 Tests | EUR 826.8 |
C3 ELISA Kit| Monkey Complement C3 ELISA Kit |
|||
EF012769 | Lifescience Market | 96 Tests | EUR 826.8 |
C4 ELISA Kit| Monkey Complement C4 ELISA Kit |
|||
EF012770 | Lifescience Market | 96 Tests | EUR 826.8 |
ANCA combi ELISA kit |
|||
55R-ORG530 | Fitzgerald | 96 wells | EUR 721.2 |
Description: ELISA kit for the detection of ANCA combi in the research laboratory |
Mouse COMT ELISA Kit |
|||
EMC0052 | Abclonal | 96Tests | EUR 625.2 |
Mouse COMP ELISA Kit |
|||
EMC0212 | Abclonal | 96Tests | EUR 625.2 |
Sheep COMT ELISA Kit |
|||
ESC0052 | Abclonal | 96Tests | EUR 625.2 |
Sheep COMP ELISA Kit |
|||
ESC0212 | Abclonal | 96Tests | EUR 625.2 |
Human COMP ELISA Kit |
|||
LF-EK50948 | Abfrontier | 1×96T | EUR 777.6 |
Human COMT ELISA Kit |
|||
ELA-E9267h | Lifescience Market | 96 Tests | EUR 988.8 |
Human COMP ELISA Kit |
|||
ELA-E1197h | Lifescience Market | 96 Tests | EUR 988.8 |
COMP ELISA KIT|Human |
|||
EF000075 | Lifescience Market | 96 Tests | EUR 826.8 |
COMT ELISA KIT|Human |
|||
EF006499 | Lifescience Market | 96 Tests | EUR 826.8 |
Human COMT ELISA Kit |
|||
EHC0052 | Abclonal | 96Tests | EUR 625.2 |
Human COMP ELISA Kit |
|||
EHC0212 | Abclonal | 96Tests | EUR 625.2 |
Monkey COMT ELISA Kit |
|||
EMKC0052 | Abclonal | 96Tests | EUR 625.2 |
Monkey COMP ELISA Kit |
|||
EMKC0212 | Abclonal | 96Tests | EUR 625.2 |
Rabbit COMT ELISA Kit |
|||
ERTC0052 | Abclonal | 96Tests | EUR 625.2 |
Rabbit COMP ELISA Kit |
|||
ERTC0212 | Abclonal | 96Tests | EUR 625.2 |
Bovine COMT ELISA Kit |
|||
EBC0052 | Abclonal | 96Tests | EUR 625.2 |
Bovine COMP ELISA Kit |
|||
EBC0212 | Abclonal | 96Tests | EUR 625.2 |
Canine COMT ELISA Kit |
|||
ECC0052 | Abclonal | 96Tests | EUR 625.2 |
Canine COMP ELISA Kit |
|||
ECC0212 | Abclonal | 96Tests | EUR 625.2 |
Rat Complement component 3b ELISA kit |
|||
E02C0113-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Rat Complement component 3b in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Complement component 3b ELISA kit |
|||
E02C0113-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A sandwich ELISA for quantitative measurement of Rat Complement component 3b in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Complement component 3b ELISA kit |
|||
E02C0113-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A sandwich ELISA for quantitative measurement of Rat Complement component 3b in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Complement Component 1R ELISA kit |
|||
E02C0352-192T | BlueGene | 192 tests | EUR 1524 |
Description: A competitive ELISA for quantitative measurement of Rat Complement Component 1R in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Complement Component 1R ELISA kit |
|||
E02C0352-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
Description: A competitive ELISA for quantitative measurement of Rat Complement Component 1R in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Complement Component 1R ELISA kit |
|||
E02C0352-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
Description: A competitive ELISA for quantitative measurement of Rat Complement Component 1R in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Complement Component 7 ELISA kit |
|||
E02C0354-192T | BlueGene | 192 tests | EUR 1524 |
Description: A sandwich ELISA for quantitative measurement of Rat Complement Component 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |