Engineering multiple species-like genetic – Informed Choice about Cancer Screening

Engineering multiple species-like genetic incompatibilities in insects

Speciation constrains the flow of genetic information between populations of sexually reproducing organisms. Gaining control over mechanisms of speciation would enable new strategies to manage wild populations of disease vectors, agricultural pests, and invasive species. Additionally, such control would provide safe biocontainment of transgenes and gene drives. Here, we demonstrate a general approach to create engineered genetic incompatibilities (EGIs) in the model insect Drosophila melanogaster.

EGI couples a dominant lethal transgene with a recessive resistance allele. Strains homozygous for both elements are fertile and fecund when they mate with similarly engineered strains, but incompatible with wild-type strains that lack resistant alleles. EGI genotypes can also be tuned to cause hybrid lethality at different developmental life-stages.

Further, we demonstrate that multiple orthogonal EGI strains of D. melanogaster can be engineered to be mutually incompatible with wild-type and with each other. EGI is a simple and robust approach in multiple sexually reproducing organisms.

CometAssay 96 Well ES Starter Kit plus EU Power Supply
4253-096-ESK-PS2	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus UK Power Supply
4253-096-ESK-PS3	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus SZ Power Supply
4253-096-ESK-PS4	Biotechne	1 Kit	EUR 4597.68

CometAssay 20 Well ES Starter Kit plus AUS Power Supply
4252-040-ESK-PS5	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus AUS Power Supply
4253-096-ESK-PS5	Biotechne	1 Kit	EUR 4597.68

CometAssay 20 Well ES Starter Kit plus Power Supply for UK
4252-040-ESK-PS3	Biotechne	1 Kit	EUR 4597.68

CometAssay Electrophoresis Starter Kit
4250-050-ESK	Biotechne	1 Kit	EUR 3749.28

CometAssay Electrophoresis Starter Kit plus EU Power Supply
4250-050-ESK-PS2	Biotechne	1 Kit	EUR 4597.68

CometAssay Electrophoresis Starter Kit plus UK Power Supply
4250-050-ESK-PS3	Biotechne	1 Kit	EUR 4597.68

CometAssay Electrophoresis Starter Kit plus SZ Power Supply
4250-050-ESK-PS4	Biotechne	1 Kit	EUR 4597.68

Pipetman Starter Kit
F167300	Scientific Laboratory Supplies	EACH	EUR 915.23

Mohs Lab Starter Kit
26417-1	Polysciences Europe GmbH	1kit	EUR 383

Pipetman L Starter Kit
F167350	Scientific Laboratory Supplies	EACH	EUR 994.14

Pipetman G Starter Kit
F167900	Scientific Laboratory Supplies	EACH	EUR 881.09

BMP21-LAB starter kit
LAB6029	Scientific Laboratory Supplies	EACH	EUR 209.76

Triple-Pure Starter Kit
SLS1420	Scientific Laboratory Supplies	PK50	EUR 236.4

HOPE® Fixative Starter Kit
24884-1	Polysciences Europe GmbH	1kit	EUR 438

ELISA Starter Pack Kit
55R-E101PK	Fitzgerald	1 kit	EUR 675.6
Description: ELISA reagent tool kit for use as a starter pack for researchers

Axygen Axypet Pro Starter Kit
PIP2740	Scientific Laboratory Supplies	EACH	EUR 1105.2

Thermal Test Film Starter Kit
PCR0892	Scientific Laboratory Supplies	EACH	EUR 344.4

Lambda Plus Pipette Starter Kit
4069	Scientific Laboratory Supplies	EACH	EUR 934.8

5mL MacroTube Starter Kit. Includes
C2500-SK	MTC Bio	1/pack	EUR 220.38
Description: 5mL MacroTubes

Cryo-EM Vitrification Starter Kit
M-CEM-VK301	MiTeGen	1 Kit	EUR 1371
Description: Cryo-EM Vitrification Starter Kit

Multipette M4 dispenser starter kit
E4982000314	Scientific Laboratory Supplies	EACH	EUR 450

Viability PCR Starter Kit with PMA
31075	Biotium	1kit	EUR 435.6
Description: Minimum order quantity: 1 unit of 1kit

Storage Case for UniPuck Starter Kit
M-CP-UPSK-C1	MiTeGen	1 CASE	EUR 300
Description: Storage Case for UniPuck Starter Kit

Viability PCR Starter Kit with PMAxxâ„¢
31075-X	Biotium	1kit	EUR 435.6
Description: Minimum order quantity: 1 unit of 1kit

Kinesis Siltite Thermo MS Starter Kit
CHR1936	Scientific Laboratory Supplies	EACH	EUR 378

Cryo-EM Puck Starter Kit Storage Case
M-CEMG2-SC1	MiTeGen	1 CASE	EUR 300
Description: Cryo-EM Puck Starter Kit Storage Case

UVT/UVH RPL. STARTER
IB46560	IBI Scientific	-	EUR 26.27

Corning Lambda EliteTouch Pipette Starter Kit
6065	Scientific Laboratory Supplies	PK25	EUR 1183.2

IsoTherm-System Starter
E3880001018	Scientific Laboratory Supplies	EACH	EUR 184.8

Mohs Lab Starter Kit with Diagnostic Stains
26418-1	Polysciences Europe GmbH	1kit	EUR 916

Spine Puck Starter Kit Protective Storage Case
M-SPSK-Case	MiTeGen	1 CASE	EUR 300
Description: Spine Puck Starter Kit Protective Storage Case

Large tissue Starter box
HOM1090	Scientific Laboratory Supplies	PK50	EUR 320.4

Protein Crystallization Starter Kit, English Version
M-CS-401EN	MiTeGen	1 Kit	EUR 156
Description: Protein Crystallization Starter Kit, English Version

Kinesis Siltite Ferrule Starter Kit 0.25mm Column
CHR1893	Scientific Laboratory Supplies	PK10	EUR 148.8

Kinesis Siltite Ferrule Starter Kit 0.32mm column
CHR1894	Scientific Laboratory Supplies	PK10	EUR 140.4

Kinesis Siltite Ferrule Starter Kit 0.53mm column
CHR1895	Scientific Laboratory Supplies	PK10	EUR 140.4

BRAND Transferpette S Starter-Kit Midi
PIP5230	Scientific Laboratory Supplies	EACH	EUR 968.4

Eppendorf 5ml Starter Pack
E0030119380	Scientific Laboratory Supplies	EACH	EUR 166.8

Neurons Starter Kit (iPSC from Blood Cells; Male)
ASE-9321K	Applied StemCell	1 Kit	EUR 473.1
Description: 12 month

BRAND Transferpette S Starter-Kit Micro
PIP5229	Scientific Laboratory Supplies	EACH	EUR 974.4

BRAND Transferpette S Starter-Kit Macro
PIP5232	Scientific Laboratory Supplies	EACH	EUR 974.4

Viability PCR Starter Kit with PMA and Enhancer
31076	Biotium	1kit	EUR 435.6
Description: Minimum order quantity: 1 unit of 1kit

starter uv tube 4w-20w
VLST151	Consort	ea	EUR 67.2

Neurons Starter Kit (iPSC from Blood Cells; Female)
ASE-9321KF	Applied StemCell	1 Kit	EUR 473.1
Description: 12 month

BRAND Transferpette S Starter-Kit Standard
PIP5231	Scientific Laboratory Supplies	EACH	EUR 972

Viability PCR Starter Kit with PMAxxâ„¢ and Enhancer
31076-X	Biotium	1kit	EUR 435.6
Description: Minimum order quantity: 1 unit of 1kit

Kinesis upchurch HPLC Starter Fittings Kit
CHR2409	Scientific Laboratory Supplies	EACH	EUR 334.23

Starter Pack Repeater Syringes
6636	Scientific Laboratory Supplies	EACH	EUR 553.2

Lambda EliteTouch Starter Pack
PIP0382	Scientific Laboratory Supplies	EACH	EUR 1050

Kinesis SILTITE FINGERTITE VARIAN INJ/MS STARTER KIT
CHR1938	Scientific Laboratory Supplies	EACH	EUR 378

Kinesis SILTITE FINGERTITE VARIAN INJ / FID STARTER KIT
CHR1937	Scientific Laboratory Supplies	EACH	EUR 378

BioMag®Plus Streptavidin / Biotin Binding Starter Kit
86030-1	Polysciences Europe GmbH	1kit	EUR 624

XT STARTER PCR96 KIT, CONTAINS XT STARTER OPEN PLATFORM ICE-FREE BENCHTOP COOLER AND COOLRACK PCR MODULE
432016	CORNING	1/pk	EUR 622.8
Description: BioCision; BioCision CoolBox

Kinesis Siltite Fingertite Inj/MS Starter Kit compatible with Agilent GC
CHR1935	Scientific Laboratory Supplies	EACH	EUR 378

Gilson TRACKMAN PIPETMAN M Bt Connected Starter Kit Pro
FB10221	Scientific Laboratory Supplies	EACH	EUR 4501.2

BioMag®Plus Protein A - Antibody Isolation Starter Kit
86040-1	Polysciences Europe GmbH	1kit	EUR 624

BioMag®Plus Protein G - Antibody Isolation Starter Kit
86050-1	Polysciences Europe GmbH	1kit	EUR 624

Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Male)
ASE-9323K	Applied StemCell	1 vial	EUR 546
Description: 12 month

XT STARTER M-PCR KIT, CONTAINS XT STARTER OPEN PLATFORM ICE-FREE BENCHTOP COOLER AND COOLRACK M-PCR MODULE
432017	CORNING	1/pk	EUR 613.2
Description: BioCision; BioCision CoolBox

Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Male)
ASE-9322PK	Applied StemCell	1 Kit	EUR 497.4
Description: 12 month

Corning XT Starter Kit complete - low profile open platform Ice-free Cooler
432014	Scientific Laboratory Supplies	1KIT	EUR 274.8

Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Female)
ASE-9323KF	Applied StemCell	1 vial	EUR 546
Description: 12 month

Triple-Pure Starter Kit, 10 each of 0.1, 0.5, 1.0, 1.5 and 3.0mm
BCM1202	Bio Basic	1 pcs, 1 UNIT	EUR 292.37

Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Female)
ASE-9322PKF	Applied StemCell	1 Kit	EUR 497.4
Description: 12 month

Starter Kit 100 Maxitips 10 dispensing parts 10 valves 2 Maxitips G
E0030050525	Scientific Laboratory Supplies	PK102	EUR 99.6

Gilson TRACKMAN PIPETMAN M Bt Connected Multi Channel Starter Kit
FB10211	Scientific Laboratory Supplies	EACH	EUR 4449.6

Multiple Head Starter Set for Genie 2
MIX5002	Scientific Laboratory Supplies	EACH	EUR 195.6

Gilson TRACKMAN PIPETMAN M Bt Connected Single Channel Starter Kit
FB10201	Scientific Laboratory Supplies	EACH	EUR 3417.6

Immunoprecipitation Starter Pack 2 x 2mL
17600235	Scientific Laboratory Supplies	EACH	EUR 757.2

Prefilled - Triple-Pure Starter Kit, 10 each of 0.1, 0.5, 1.0, 1.5 and 3.0mm
D1032-SK	Benchmark Scientific	1 PC	EUR 178.4

Distel Dosing System Starter Pack 6x1 Litre
CLE1144	Scientific Laboratory Supplies	EACH	EUR 164.4

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203APEAQUSP	Scientific Laboratory Supplies	EACH	EUR 492

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203APEORGSP	Scientific Laboratory Supplies	EACH	EUR 492

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203NPEAQUSP	Scientific Laboratory Supplies	EACH	EUR 471.6

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203NPENYLSP	Scientific Laboratory Supplies	EACH	EUR 469.2

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203NPEORGSP	Scientific Laboratory Supplies	EACH	EUR 471.6

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203NPEPPSP	Scientific Laboratory Supplies	EACH	EUR 469.2

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203NPUAQUSP	Scientific Laboratory Supplies	EACH	EUR 471.6

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGN203NPUORGSP	Scientific Laboratory Supplies	EACH	EUR 471.6

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGS203NPEORGSP	Scientific Laboratory Supplies	EACH	EUR 484.8

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P
WHAGS203NPUORGSP	Scientific Laboratory Supplies	EACH	EUR 484.8

Precellys 2mL Lysing Kits - Soft tissue Starter box
HOM1060	Scientific Laboratory Supplies	PK40	EUR 238.8

Finntip 10 0.2-10ul Pink refill starter kit - 4 x 192 rack plus 10 x 192 refill
PIP3646	Scientific Laboratory Supplies	EACH	EUR 274.8

AXYGEN® AXYPET® PRO STARTER KIT: 4 PIPETTORS, PLEXI STAND, SAMPLE TIPS
AP-STR-KIT-P	CORNING	1/pk	EUR 865.2
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

BioMag®Plus Goat anti-Mouse IgG Particle Antibody Coupling Starter Kit
86020-1	Polysciences Europe GmbH	1kit	EUR 624

Finntip Flex 1000 50-1000ul Blue Refill starter kit 1 x 96 rack + 16 x 96 rack
PIP3696	Scientific Laboratory Supplies	EACH	EUR 199.2

hybex Media Storage Bottle Starter Pack Blue Cap
BOT1866	Scientific Laboratory Supplies	EACH	EUR 223.26

Precellys 2mL Lysing Kits - Micro-organism Starter box
HOM1062	Scientific Laboratory Supplies	PK40	EUR 238.8

NextPette Starter Pack 0.5-10 2-20 20-200 100-1000
PIP1351	Scientific Laboratory Supplies	EACH	EUR 787.2

NextPette Starter Pack 20-200 100-1000 1-5 1-10
PIP1352	Scientific Laboratory Supplies	EACH	EUR 818.4

hybex Media Storage Bottle Starter Pack Green Cap
BOT1874	Scientific Laboratory Supplies	EACH	EUR 223.26

hybex Media Storage Bottle Starter Pack White Cap
BOT1890	Scientific Laboratory Supplies	EACH	EUR 223.26

hybex Media Storage Bottle Starter Pack Purple Cap
BOT1882	Scientific Laboratory Supplies	EACH	EUR 223.26

hybex Media Storage Bottle Starter Pack Yellow Cap
BOT1898	Scientific Laboratory Supplies	EACH	EUR 223.26

Finntip Flex 10 0.1-10ul Pink Refill starter kit 1 x 96 rack + 20 x 96 refills
PIP3652	Scientific Laboratory Supplies	EACH	EUR 219.6

myGel Mini Electrophoresis System Starter Kit (Includes E1101, A1701 and W4000-100)
E1101-SK	Benchmark Scientific	1 each	EUR 712.8

Finntip Flex 200 5-200ul Yellow Refill starter kit 1 x 96 rack + 20 x 96 refill
PIP3664	Scientific Laboratory Supplies	EACH	EUR 219.6

Finntip Flex 300 5-300ul Orange Refill starter kit 1 x 96 rack + 20 x 96 refill
PIP3682	Scientific Laboratory Supplies	EACH	EUR 219.6

Eppendorf PCR Cooler 0.2 ml Starter 1x pink 1x blue
E3881000015	Scientific Laboratory Supplies	EACH	EUR 123.6

hybex Media Storage Bottle Starter Pack Assorted Caps
BOT1906	Scientific Laboratory Supplies	EACH	EUR 223.26

XT Starter holder only open platform ice free cooler
432015	Scientific Laboratory Supplies	EACH	EUR 86.4

Finntip Flex 1200 50-1200ul Turquoise Refill starter kit 1 x 96 rack + 16 x 96 refill
PIP3704	Scientific Laboratory Supplies	EACH	EUR 355.2

myGel Mini Electrophoresis System Starter Kit (Includes E1101-E, A1701 and W4000-100)
E1101-SK-E	Benchmark Scientific	1 PC	EUR 742.5

Eppendorf UVette DNA RNAse And Protease Free Starter Set
E4099100007	Scientific Laboratory Supplies	EACH	EUR 106.8

IsoTherm-System Starter Set for micro test tubes 0.5 ml
E3880000011	Scientific Laboratory Supplies	EACH	EUR 184.8

AXYPET STARTER KIT 1 AP-20, AP-200 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS
AP-STR-KIT-1	CORNING	1/pk	EUR 426
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

AXYPET STARTER KIT 2 AP-10, AP-100 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS
AP-STR-KIT-2	CORNING	1/pk	EUR 440.4
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Corning DWorks 1-200uL Pipet Tips Reload Starter Kit Nonsterile 96tip/Deck 10 Decks/Pack 960tip/Pack
4132	Scientific Laboratory Supplies	PK960	EUR 85.2

Eppendorf Conical Tubes 25mL with snap cap Starter Pack PCR clean
E0030118502	Scientific Laboratory Supplies	EACH	EUR 120

Eppendorf Conical Tubes 25mL with screw cap Starter Pack PCR clean
E0030122500	Scientific Laboratory Supplies	EACH	EUR 123.6

Corning 3D Clear Starter Kit - Includes Reagent/Antibody Buffer/Blocking Buffer/Penetration Buffer/Washing Buffers
5730	Scientific Laboratory Supplies	EACH	EUR 955.2

BeadBug(TM) prefilled tubes; 2.0 mL capacity; Triple-Pure starter kit; with 10 each of 0.1; 0.5; 1.0; 1.5 and 3.0 mm Zirconium beads
Z763810-1KT	Scientific Laboratory Supplies	PK50	EUR 177.6

hybex™ Media storage bottle, STARTER PACK (GL45) blue cap (Includes 2x100ml, 3x250ml, 3x500ml and 2x1000ml)
B3000-SP-B	Benchmark Scientific	1 each	EUR 146.7

Aberrant Early Growth of Individual Trigeminal Sensory and Motor Axons in a Series of Mouse Genetic Models of 22q11.2 Deletion Syndrome

We identified divergent modes of initial axon growth that prefigure disrupted differentiation of the trigeminal nerve (CN V), a cranial nerve essential for suckling, feeding and swallowing (S/F/S), a key innate behavior compromised in multiple genetic developmental disorders including DiGeorge/22q11.2 Deletion Syndrome (22q11.2 DS). We combined rapid in vivo labeling of single CN V axons in LgDel+/- mouse embryos, a genomically accurate 22q11.2DS model, and 3-dimensional imaging to identify and quantify phenotypes that could not be resolved using existing methods.
We assessed these phenotypes in three 22q11.2-related genotypes to determine whether individual CN V motor and sensory axons wander, branch and sprout aberrantly in register with altered anterior-posterior hindbrain patterning and gross morphological disruption of CN V seen in LgDel+/-. In the additional 22q11.2-related genotypes: Tbx1+/-, Ranbp1-/-, Ranbp1+/-, and LgDel+/-:Raldh2+/-; axon phenotypes are seen when hindbrain patterning and CN V gross morphology is altered, but not when it is normal or restored toward WT.
This disordered growth of CN V sensory and motor axons, whose appropriate targeting is critical for optimal S/F/S, may be an early, critical determinant of imprecise innervation leading to inefficient oropharyngeal function associated with 22q11.2 deletion from birth onward.

A Faster and More Accurate Algorithm for Calculating Population Genetics Statistics Requiring Sums of Stirling Numbers of the First Kind

Ewen’s sampling formula is a foundational theoretical result that connects probability and number theory with molecular genetics and molecular evolution; it was the analytical result required for testing the neutral theory of evolution, and has since been directly or indirectly utilized in a number of population genetics statistics.

Ewen’s sampling formula, in turn, is deeply connected to Stirling numbers of the first kind. Here, we explore the cumulative distribution function of these Stirling numbers, which enables a single direct estimate of the sum, using representations in terms of the incomplete beta function.

This estimator enables an improved method for calculating an asymptotic estimate for one useful statistic, Fu’s F_s By reducing the calculation from a sum of terms involving Stirling numbers to a single estimate, we simultaneously improve accuracy and dramatically increase speed

Quantitative genetic architecture of adaptive phenology traits in the deciduous tree, Populus trichocarpa (Torr. and Gray)

In a warming climate, the ability to accurately predict and track shifting environmental conditions will be fundamental for plant survival. Environmental cues define the transitions between growth and dormancy as plants synchronise development with favourable environmental conditions, however these cues are predicted to change under future climate projections which may have profound impacts on tree survival and growth.

Here, we use a quantitative genetic approach to estimate the genetic basis of spring and autumn phenology in Populus trichocarpa to determine this species capacity for climate adaptation. We measured bud burst, leaf coloration, and leaf senescence traits across two years (2017-2018) and combine these observations with measures of lifetime growth to determine how genetic correlations between phenology and growth may facilitate or constrain adaptation. Timing of transitions differed between years, although we found strong cross year genetic correlations in all traits, suggesting that genotypes respond in consistent ways to seasonal cues.

Spring and autumn phenology were correlated with lifetime growth, where genotypes that burst leaves early and shed them late had the highest lifetime growth. We also identified substantial heritable variation in the timing of all phenological transitions (h² = 0.5-0.8) and in lifetime growth (h² = 0.8).

The combination of additive variation and favourable genetic correlations in phenology traits suggests that populations of cultivated varieties of P. Trichocarpa may have the capability to adapt their phenology to climatic changes without negative impacts on growth

OxiSelect Comet Assay Kit (3-Well Slides)
STA-351-5	Cell Biolabs	5 x 75 assays	EUR 2836.8
Description: Our OxiSelect 3-Well Comet Assay Kits provide a fast, convenient way to screen for general DNA damage, regardless of the source or nature of the damage. Kits include Comet Slides, reagents, and a fluorescent dye to visualize cells under an epifluorescence microscope.

CometAssay Electrophoresis Starter Kit
4250-050-ESK	Biotechne	1 Kit	EUR 3749.28

CometAssay 20 Well ES Starter Kit plus NA Power Supply
4252-040-ESK-PS1	Biotechne	1 Kit	EUR 4597.68

CometAssay 20 Well ES Starter Kit plus EU Power Supply
4252-040-ESK-PS2	Biotechne	1 Kit	EUR 4597.68

CometAssay 20 Well ES Starter Kit plus SZ Power Supply
4252-040-ESK-PS4	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus NA Power Supply
4253-096-ESK-PS1	Biotechne	1 Kit	EUR 4528.8

CometAssay 96 Well ES Starter Kit plus EU Power Supply
4253-096-ESK-PS2	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus UK Power Supply
4253-096-ESK-PS3	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus SZ Power Supply
4253-096-ESK-PS4	Biotechne	1 Kit	EUR 4597.68

CometAssay 20 Well ES Starter Kit plus AUS Power Supply
4252-040-ESK-PS5	Biotechne	1 Kit	EUR 4597.68

CometAssay 96 Well ES Starter Kit plus AUS Power Supply
4253-096-ESK-PS5	Biotechne	1 Kit	EUR 4597.68

CometAssay 20 Well ES Starter Kit plus Power Supply for UK
4252-040-ESK-PS3	Biotechne	1 Kit	EUR 4597.68

CometSlide
4250-200-03	Biotechne	100 slides	EUR 520.32

CometAssay 96
4253-096-K	Biotechne	96 tests	EUR 513.6

Cometslides
4250-004-03	Biotechne	2 Tests	EUR 150.72

Cometslides
4250-050-03	Biotechne	25 Each	EUR 256.56

CometAssay HT Slide
4252-040-01	Biotechne	2 Tests	EUR 170.88

CometAssay HT Slide
4252-200-01	Biotechne	10 Tests	EUR 436.32

CometAssay HT Slide
4252-500-01	Biotechne	25 Tests	EUR 684.96

CometAssay Electrophoresis Starter Kit plus EU Power Supply
4250-050-ESK-PS2	Biotechne	1 Kit	EUR 4597.68

CometAssay Electrophoresis Starter Kit plus UK Power Supply
4250-050-ESK-PS3	Biotechne	1 Kit	EUR 4597.68

CometAssay Electrophoresis Starter Kit plus SZ Power Supply
4250-050-ESK-PS4	Biotechne	1 Kit	EUR 4597.68

96-Well CometSlides
4253-096-03	Biotechne	1 Tests	EUR 170.88

CometAssay LMAgarose
4250-050-02	Biotechne	15 mL	EUR 165.84

CometAssay LMAgarose
4250-500-02	Biotechne	100 mL	EUR 562.32

Cometslides Rack System
4252-040-02	Biotechne	1 Each	EUR 256.56

CometAssay Lysis Solution
4250-010-01	Biotechne	100 mL	EUR 189.36

CometAssay Lysis Solution (2 x 500 mL)
4250-050-01	Biotechne	1 L	EUR 219.6

OxiSelect Comet Assay Slides (3-Well)
STA-352	Cell Biolabs	5 slides	EUR 261.6
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

OxiSelect Comet Assay Slides (3-Well)
STA-353	Cell Biolabs	25 slides	EUR 435.6
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

OxiSelect Comet Assay Slides (3-Well)
STA-353-5	Cell Biolabs	5 x 25 slides	EUR 1521.6
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

OxiSelect 96-Well Comet Assay Slide
STA-356	Cell Biolabs	1 slide	EUR 219.6
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

OxiSelect 96-Well Comet Assay Slide
STA-356-5	Cell Biolabs	5 slides	EUR 622.8
Description: The OxiSelect Comet Assay Slides are useful as a screening tool for various types of DNA damage. Slides are specially treated for adhesion of low-melting agarose. Easily visualize results by epifluorescence microscopy.

OxiSelect Comet Assay Control Cells
STA-354	Cell Biolabs	1 set	EUR 303.6
Description: OxiSelect Comet Assay Control Cells are a set of two cell lines that serve as a positive control (Etoposide-treated) and a negative control (untreated) respectively.

CometAssay High Throughput Slides
4252-02K-01	Biotechne	100 tests	EUR 1943.28

CometAssay Neutral Control Slides
4257-010-NC	Biotechne	10 Tests	EUR 389.28

CometAssay Alkaline Control Slides
4256-010-CC	Biotechne	10 Tests	EUR 389.28

CometAssay Electrophoresis System
4250-050-ES	Biotechne	1 Kit	EUR 3540.96

CometAssay Single Cell Gel Electrophoresis Assay
4250-050-K	Biotechne	50 tests	EUR 513.6

CometAssay Single Cell Gel Electrophoresis Assay-Silver
4251-050-K	Biotechne	1 kit	EUR 684.96

COMPtrol Kit
CMIGP-08-2K	Spherotech	1x2 mL (fluorescent)	EUR 327.6
Description: Please reffer to the technical data sheet for more detail information for this item. Our dedicated team would be happy to assist you via live chat, email or phone.

C3 ELISA Kit\| Rat Complement Component 3 ELISA Kit
EF016915	Lifescience Market	96 Tests	EUR 826.8

C4 ELISA Kit\| Rat Complement Component 4 ELISA Kit
EF016949	Lifescience Market	96 Tests	EUR 826.8

C6 ELISA Kit\| Rat Complement component C6 ELISA Kit
EF018502	Lifescience Market	96 Tests	EUR 826.8

C5 ELISA Kit\| Rat Complement Component 5 ELISA Kit
EF017579	Lifescience Market	96 Tests	EUR 826.8

C9 ELISA Kit\| Rat Complement Component 9 ELISA Kit
EF017581	Lifescience Market	96 Tests	EUR 826.8

C3a ELISA Kit\| Rat Complement Component 3a ELISA Kit
EF016916	Lifescience Market	96 Tests	EUR 826.8

C4a ELISA Kit\| Rat Complement Component 4a ELISA Kit
EF016950	Lifescience Market	96 Tests	EUR 826.8

C5a ELISA Kit\| Rat Complement Component 5a ELISA Kit
EF017580	Lifescience Market	96 Tests	EUR 826.8

C4 ELISA Kit\| Mouse Complement Component 4 ELISA Kit
EF012783	Lifescience Market	96 Tests	EUR 826.8

C9 ELISA Kit\| Mouse Complement component C9 ELISA Kit
EF014543	Lifescience Market	96 Tests	EUR 826.8

Comt/ Rat Comt ELISA Kit
ELI-46977r	Lifescience Market	96 Tests	EUR 1063.2

COMP/ Rat COMP ELISA Kit
ELA-E1197r	Lifescience Market	96 Tests	EUR 1063.2

Comp/ Rat Comp ELISA Kit
ELI-03952r	Lifescience Market	96 Tests	EUR 1063.2

C3 ELISA Kit\| Monkey Complement Component 3 ELISA Kit
EF012684	Lifescience Market	96 Tests	EUR 826.8

C4 ELISA Kit\| Monkey Complement Component 4 ELISA Kit
EF012685	Lifescience Market	96 Tests	EUR 826.8

C3a ELISA Kit\| Mouse Complement Component 3a ELISA Kit
EF012782	Lifescience Market	96 Tests	EUR 826.8

C4a ELISA Kit\| Mouse Complement Component 4a ELISA Kit
EF013475	Lifescience Market	96 Tests	EUR 826.8

C5a ELISA Kit\| Mouse Complement Component 5a ELISA Kit
EF013476	Lifescience Market	96 Tests	EUR 826.8

C6 ELISA Kit\| Bovine Complement component C6 ELISA Kit
EF011249	Lifescience Market	96 Tests	EUR 826.8

C9 ELISA Kit\| Bovine Complement component C9 ELISA Kit
EF011250	Lifescience Market	96 Tests	EUR 826.8

C3a ELISA Kit\| Sheep Complement Component 3a ELISA Kit
EF019499	Lifescience Market	96 Tests	EUR 826.8

C5a ELISA Kit\| Monkey Complement Component 5a ELISA Kit
EF012686	Lifescience Market	96 Tests	EUR 826.8

C3 ELISA Kit\| Porcine Complement Component 3 ELISA Kit
EF016572	Lifescience Market	96 Tests	EUR 826.8

C3a ELISA Kit\| Rabbit Complement Component 3a ELISA Kit
EF016782	Lifescience Market	96 Tests	EUR 826.8

C5a ELISA Kit\| Rabbit Complement Component 5a ELISA Kit
EF016783	Lifescience Market	96 Tests	EUR 826.8

C3a ELISA Kit\| Porcine Complement Component 3a ELISA Kit
EF016573	Lifescience Market	96 Tests	EUR 826.8

C5a ELISA Kit\| Porcine Complement Component 5a ELISA Kit
EF016574	Lifescience Market	96 Tests	EUR 826.8

Commd5/ Rat Commd5 ELISA Kit
ELI-50340r	Lifescience Market	96 Tests	EUR 1063.2

Commd3/ Rat Commd3 ELISA Kit
ELI-50778r	Lifescience Market	96 Tests	EUR 1063.2

C3 ELISA Kit\| Guinea pig Complement Component 3 ELISA Kit
EF012601	Lifescience Market	96 Tests	EUR 826.8

Cd93 ELISA Kit\| Rat Complement component C1q receptor ELISA Kit
EF018448	Lifescience Market	96 Tests	EUR 826.8

C8b ELISA Kit\| Rat Complement component C8 beta chain ELISA Kit
EF018503	Lifescience Market	96 Tests	EUR 826.8

Rat COMT ELISA Kit
ERC0052	Abclonal	96Tests	EUR 625.2

Rat COMP ELISA Kit
ERC0212	Abclonal	96Tests	EUR 625.2

Rat COMP ELISA Kit
STJ150493	St John's Laboratory	1 kit	EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of COMP in Rat serum, plasma and other biological fluids

Goat COMT ELISA Kit
EGTC0052	Abclonal	96Tests	EUR 625.2

Goat COMP ELISA Kit
EGTC0212	Abclonal	96Tests	EUR 625.2

C3 ELISA Kit\| Mouse Complement C3 ELISA Kit
EF012781	Lifescience Market	96 Tests	EUR 826.8

C5 ELISA Kit\| Mouse Complement C5 ELISA Kit
EF013316	Lifescience Market	96 Tests	EUR 826.8

C3 ELISA Kit\| Monkey Complement C3 ELISA Kit
EF012769	Lifescience Market	96 Tests	EUR 826.8

C4 ELISA Kit\| Monkey Complement C4 ELISA Kit
EF012770	Lifescience Market	96 Tests	EUR 826.8

ANCA combi ELISA kit
55R-ORG530	Fitzgerald	96 wells	EUR 721.2
Description: ELISA kit for the detection of ANCA combi in the research laboratory

Mouse COMT ELISA Kit
EMC0052	Abclonal	96Tests	EUR 625.2

Mouse COMP ELISA Kit
EMC0212	Abclonal	96Tests	EUR 625.2

Sheep COMT ELISA Kit
ESC0052	Abclonal	96Tests	EUR 625.2

Sheep COMP ELISA Kit
ESC0212	Abclonal	96Tests	EUR 625.2

Human COMP ELISA Kit
LF-EK50948	Abfrontier	1Ã—96T	EUR 777.6

Human COMT ELISA Kit
ELA-E9267h	Lifescience Market	96 Tests	EUR 988.8

Human COMP ELISA Kit
ELA-E1197h	Lifescience Market	96 Tests	EUR 988.8

COMP ELISA KIT\|Human
EF000075	Lifescience Market	96 Tests	EUR 826.8

COMT ELISA KIT\|Human
EF006499	Lifescience Market	96 Tests	EUR 826.8

Human COMT ELISA Kit
EHC0052	Abclonal	96Tests	EUR 625.2

Human COMP ELISA Kit
EHC0212	Abclonal	96Tests	EUR 625.2

Monkey COMT ELISA Kit
EMKC0052	Abclonal	96Tests	EUR 625.2

Monkey COMP ELISA Kit
EMKC0212	Abclonal	96Tests	EUR 625.2

Rabbit COMT ELISA Kit
ERTC0052	Abclonal	96Tests	EUR 625.2

Rabbit COMP ELISA Kit
ERTC0212	Abclonal	96Tests	EUR 625.2

Bovine COMT ELISA Kit
EBC0052	Abclonal	96Tests	EUR 625.2

Bovine COMP ELISA Kit
EBC0212	Abclonal	96Tests	EUR 625.2

Canine COMT ELISA Kit
ECC0052	Abclonal	96Tests	EUR 625.2

Canine COMP ELISA Kit
ECC0212	Abclonal	96Tests	EUR 625.2

Rat Complement component 3b ELISA kit
E02C0113-192T	BlueGene	192 tests	EUR 1524

Description: A sandwich ELISA for quantitative measurement of Rat Complement component 3b in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Complement component 3b ELISA kit
E02C0113-48	BlueGene	1 plate of 48 wells	EUR 624

Description: A sandwich ELISA for quantitative measurement of Rat Complement component 3b in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Complement component 3b ELISA kit
E02C0113-96	BlueGene	1 plate of 96 wells	EUR 822

Description: A sandwich ELISA for quantitative measurement of Rat Complement component 3b in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Complement Component 1R ELISA kit
E02C0352-192T	BlueGene	192 tests	EUR 1524

Description: A competitive ELISA for quantitative measurement of Rat Complement Component 1R in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Complement Component 1R ELISA kit
E02C0352-48	BlueGene	1 plate of 48 wells	EUR 624

Description: A competitive ELISA for quantitative measurement of Rat Complement Component 1R in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Complement Component 1R ELISA kit
E02C0352-96	BlueGene	1 plate of 96 wells	EUR 822

Description: A competitive ELISA for quantitative measurement of Rat Complement Component 1R in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Complement Component 7 ELISA kit
E02C0354-192T	BlueGene	192 tests	EUR 1524

Description: A sandwich ELISA for quantitative measurement of Rat Complement Component 7 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Engineering multiple species-like genetic incompatibilities in insects

CometAssay 96 Well ES Starter Kit plus EU Power Supply

CometAssay 96 Well ES Starter Kit plus UK Power Supply

CometAssay 96 Well ES Starter Kit plus SZ Power Supply

CometAssay 20 Well ES Starter Kit plus AUS Power Supply

CometAssay 96 Well ES Starter Kit plus AUS Power Supply

CometAssay 20 Well ES Starter Kit plus Power Supply for UK

CometAssay Electrophoresis Starter Kit

CometAssay Electrophoresis Starter Kit plus EU Power Supply

CometAssay Electrophoresis Starter Kit plus UK Power Supply

CometAssay Electrophoresis Starter Kit plus SZ Power Supply

Pipetman Starter Kit

Mohs Lab Starter Kit

Pipetman L Starter Kit

Pipetman G Starter Kit

BMP21-LAB starter kit

Triple-Pure Starter Kit

HOPE® Fixative Starter Kit

ELISA Starter Pack Kit

Axygen Axypet Pro Starter Kit

Thermal Test Film Starter Kit

Lambda Plus Pipette Starter Kit

5mL MacroTube Starter Kit. Includes

Cryo-EM Vitrification Starter Kit

Multipette M4 dispenser starter kit

Viability PCR Starter Kit with PMA

Storage Case for UniPuck Starter Kit

Viability PCR Starter Kit with PMAxxâ„¢

Kinesis Siltite Thermo MS Starter Kit

Cryo-EM Puck Starter Kit Storage Case

UVT/UVH RPL. STARTER

Corning Lambda EliteTouch Pipette Starter Kit

IsoTherm-System Starter

Mohs Lab Starter Kit with Diagnostic Stains

Spine Puck Starter Kit Protective Storage Case

Large tissue Starter box

Protein Crystallization Starter Kit, English Version

Kinesis Siltite Ferrule Starter Kit 0.25mm Column

Kinesis Siltite Ferrule Starter Kit 0.32mm column

Kinesis Siltite Ferrule Starter Kit 0.53mm column

BRAND Transferpette S Starter-Kit Midi

Eppendorf 5ml Starter Pack

Neurons Starter Kit (iPSC from Blood Cells; Male)

BRAND Transferpette S Starter-Kit Micro

BRAND Transferpette S Starter-Kit Macro

Viability PCR Starter Kit with PMA and Enhancer

starter uv tube 4w-20w

Neurons Starter Kit (iPSC from Blood Cells; Female)

BRAND Transferpette S Starter-Kit Standard

Viability PCR Starter Kit with PMAxxâ„¢ and Enhancer

Kinesis upchurch HPLC Starter Fittings Kit

Starter Pack Repeater Syringes

Lambda EliteTouch Starter Pack

Kinesis SILTITE FINGERTITE VARIAN INJ/MS STARTER KIT

Kinesis SILTITE FINGERTITE VARIAN INJ / FID STARTER KIT

BioMag®Plus Streptavidin / Biotin Binding Starter Kit

XT STARTER PCR96 KIT, CONTAINS XT STARTER OPEN PLATFORM ICE-FREE BENCHTOP COOLER AND COOLRACK PCR MODULE

Kinesis Siltite Fingertite Inj/MS Starter Kit compatible with Agilent GC

Gilson TRACKMAN PIPETMAN M Bt Connected Starter Kit Pro

BioMag®Plus Protein A - Antibody Isolation Starter Kit

BioMag®Plus Protein G - Antibody Isolation Starter Kit

Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Male)

XT STARTER M-PCR KIT, CONTAINS XT STARTER OPEN PLATFORM ICE-FREE BENCHTOP COOLER AND COOLRACK M-PCR MODULE

Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Male)

Corning XT Starter Kit complete - low profile open platform Ice-free Cooler

Dopaminergic Neurons Starter Kit (iPSC from Blood Cells; Female)

Triple-Pure Starter Kit, 10 each of 0.1, 0.5, 1.0, 1.5 and 3.0mm

Astrocytes Precursors Starter Kit (iPSC from Blood Cells; Female)

Starter Kit 100 Maxitips 10 dispensing parts 10 valves 2 Maxitips G

Gilson TRACKMAN PIPETMAN M Bt Connected Multi Channel Starter Kit

Multiple Head Starter Set for Genie 2

Gilson TRACKMAN PIPETMAN M Bt Connected Single Channel Starter Kit

Immunoprecipitation Starter Pack 2 x 2mL

Prefilled - Triple-Pure Starter Kit, 10 each of 0.1, 0.5, 1.0, 1.5 and 3.0mm

Distel Dosing System Starter Pack 6x1 Litre

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P

WHATMAN(R) MINI-UNIPREP(TM) G2 STARTER P