Engineering multiple species-like genetic incompatibilities in insects
Speciation constrains the flow of genetic information between populations of sexually reproducing organisms. Gaining control over mechanisms of speciation would enable new strategies to manage wild populations of disease vectors, agricultural pests, and invasive species. Additionally, such control would provide safe biocontainment of transgenes and gene drives. Here, we demonstrate a general approach to create engineered genetic incompatibilities (EGIs) in the model insect Drosophila melanogaster.
EGI couples a dominant lethal transgene with a recessive resistance allele. Strains homozygous for both elements are fertile and fecund when they mate with similarly engineered strains, but incompatible with wild-type strains that lack resistant alleles. EGI genotypes can also be tuned to cause hybrid lethality at different developmental life-stages.
Further, we demonstrate that multiple orthogonal EGI strains of D. melanogaster can be engineered to be mutually incompatible with wild-type and with each other. EGI is a simple and robust approach in multiple sexually reproducing organisms.
CometAssay 96 Well ES Starter Kit plus NA Power Supply |
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| 4253-096-ESK-PS1 | Biotechne | 1 Kit | EUR 3774 |
CometAssay 96 Well ES Starter Kit plus EU Power Supply |
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| 4253-096-ESK-PS2 | Biotechne | 1 Kit | EUR 3831.4 |
CometAssay 96 Well ES Starter Kit plus UK Power Supply |
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| 4253-096-ESK-PS3 | Biotechne | 1 Kit | EUR 3831.4 |
CometAssay 96 Well ES Starter Kit plus SZ Power Supply |
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| 4253-096-ESK-PS4 | Biotechne | 1 Kit | EUR 3831.4 |
CometAssay 96 Well ES Starter Kit plus AUS Power Supply |
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| 4253-096-ESK-PS5 | Biotechne | 1 Kit | EUR 3831.4 |
CometAssay 20 Well ES Starter Kit plus Power Supply for UK |
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| 4252-040-ESK-PS3 | Biotechne | 1 Kit | EUR 3831.4 |
AXYGEN® AXYPET® PRO STARTER KIT: 4 PIPETTORS, PLEXI STAND, SAMPLE TIPS |
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| AP-STR-KIT-P | CORNING | 1/pk | EUR 721 |
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Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
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ES/ Rat ES ELISA Kit |
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| ELA-E0542r | Lifescience Market | 96 Tests | EUR 886 |
LAMBDA PLUS STARTER KIT |
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| 4069 | CORNING | 1/pk | EUR 643 |
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Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors |
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CometAssay Electrophoresis Starter Kit |
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| 4250-050-ESK | Biotechne | 1 Kit | EUR 3124.4 |
ELISA Starter Pack Kit |
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| 55R-E101PK | Fitzgerald | 1 kit | EUR 563 |
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Description: ELISA reagent tool kit for use as a starter pack for researchers |
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AXYPET STARTER KIT 1 AP-20, AP-200 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS |
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| AP-STR-KIT-1 | CORNING | 1/pk | EUR 355 |
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Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
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AXYPET STARTER KIT 2 AP-10, AP-100 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS |
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| AP-STR-KIT-2 | CORNING | 1/pk | EUR 367 |
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Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
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5mL MacroTube Starter Kit. Includes |
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| C2500-SK | MTC Bio | 1/pack | EUR 183.65 |
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Description: 5mL MacroTubes |
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Prefilled - Triple-Pure Starter Kit |
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| D1032-SK | Benchmark Scientific | 1 PC | EUR 194.63 |
ES 936 |
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| B5514-10 | ApexBio | 10 mg | EUR 284 |
ES 936 |
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| B5514-50 | ApexBio | 50 mg | EUR 1043 |
Sheep ES ELISA Kit |
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| ESE0010 | Abclonal | 96Tests | EUR 521 |
Sheep ES ELISA Kit |
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| ESE0321 | Abclonal | 96Tests | EUR 521 |
Mouse ES ELISA Kit |
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| EME0010 | Abclonal | 96Tests | EUR 521 |
Mouse ES ELISA Kit |
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| EME0027 | Abclonal | 96Tests | EUR 521 |
Mouse ES ELISA Kit |
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| EME0121 | Abclonal | 96Tests | EUR 521 |
Monkey ES ELISA Kit |
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| EMKE0010 | Abclonal | 96Tests | EUR 521 |
Monkey ES ELISA Kit |
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| EMKE0321 | Abclonal | 96Tests | EUR 521 |
Mouse ES ELISA Kit |
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| EMM21 | Abclonal | 96Tests | EUR 521 |
Porcine ES ELISA Kit |
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| EPE0010 | Abclonal | 96Tests | EUR 521 |
Porcine ES ELISA Kit |
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| EPE0027 | Abclonal | 96Tests | EUR 521 |
Porcine ES ELISA Kit |
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| EPE0121 | Abclonal | 96Tests | EUR 521 |
Porcine ES ELISA Kit |
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| EPE0321 | Abclonal | 96Tests | EUR 521 |
Rat ES ELISA Kit |
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| ERE0010 | Abclonal | 96Tests | EUR 521 |
Rat ES ELISA Kit |
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| ERE0027 | Abclonal | 96Tests | EUR 521 |
Rat ES ELISA Kit |
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| ERE0121 | Abclonal | 96Tests | EUR 521 |
Rat ES ELISA Kit |
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| ERE0321 | Abclonal | 96Tests | EUR 521 |
Rabbit ES ELISA Kit |
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| ERTE0010 | Abclonal | 96Tests | EUR 521 |
Rabbit ES ELISA Kit |
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| ERTE0027 | Abclonal | 96Tests | EUR 521 |
Rabbit ES ELISA Kit |
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| ERTE0121 | Abclonal | 96Tests | EUR 521 |
Rabbit ES ELISA Kit |
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| ERTE0321 | Abclonal | 96Tests | EUR 521 |
Anserini ES ELISA Kit |
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| EAE0010 | Abclonal | 96Tests | EUR 521 |
Anserini ES ELISA Kit |
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| EAE0027 | Abclonal | 96Tests | EUR 521 |
Anserini ES ELISA Kit |
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| EAE0121 | Abclonal | 96Tests | EUR 521 |
Goat ES ELISA Kit |
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| EGTE0010 | Abclonal | 96Tests | EUR 521 |
Goat ES ELISA Kit |
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| EGTE0027 | Abclonal | 96Tests | EUR 521 |
Goat ES ELISA Kit |
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| EGTE0121 | Abclonal | 96Tests | EUR 521 |
Goat ES ELISA Kit |
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| EGTE0321 | Abclonal | 96Tests | EUR 521 |
Canine ES ELISA Kit |
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| ECE0010 | Abclonal | 96Tests | EUR 521 |
Canine ES ELISA Kit |
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| ECE0027 | Abclonal | 96Tests | EUR 521 |
Canine ES ELISA Kit |
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| ECE0121 | Abclonal | 96Tests | EUR 521 |
Canine ES ELISA Kit |
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| ECE0321 | Abclonal | 96Tests | EUR 521 |
Chicken ES ELISA Kit |
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| ECKE0010 | Abclonal | 96Tests | EUR 521 |
Chicken ES ELISA Kit |
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| ECKE0321 | Abclonal | 96Tests | EUR 521 |
Human ES ELISA Kit |
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| EHE0010 | Abclonal | 96Tests | EUR 521 |
Human ES ELISA Kit |
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| EHE0027 | Abclonal | 96Tests | EUR 521 |
Human ES ELISA Kit |
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| EHE0121 | Abclonal | 96Tests | EUR 521 |
Bovine ES ELISA Kit |
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| EBE0010 | Abclonal | 96Tests | EUR 521 |
Bovine ES ELISA Kit |
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| EBE0027 | Abclonal | 96Tests | EUR 521 |
Bovine ES ELISA Kit |
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| EBE0121 | Abclonal | 96Tests | EUR 521 |
Bovine ES ELISA Kit |
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| EBE0321 | Abclonal | 96Tests | EUR 521 |
ES(Estrogen) ELISA Kit |
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| EU0202 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 9.375pg/ml |
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ES ELISA KIT|Human |
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| EF006881 | Lifescience Market | 96 Tests | EUR 689 |
Viability PCR Starter Kit with PMA |
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| 31075 | Biotium | 1kit | EUR 363 |
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Description: Minimum order quantity: 1 unit of 1kit |
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Viability PCR Starter Kit with PMAxxâ„¢ |
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| 31075-X | Biotium | 1kit | EUR 363 |
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Description: Minimum order quantity: 1 unit of 1kit |
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Pipette Stand Starter Kits |
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| P7700-S1 | Benchmark Scientific | 1 PC | EUR 507.83 |
Pipette Stand Starter Kits |
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| P7700-S2 | Benchmark Scientific | 1 PC | EUR 526.1 |
BrightGreen Express 2X qPCR MasterMix-No Dye |
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| MasterMix-ES | ABM | 4 x 1.25 ml for 500 reactions (20 ul) | EUR 140 |
rabbit Endostatin,ES ELISA Kit |
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| GA-E0071RB-48T | GenAsia Biotech | 48T | EUR 326 |
rabbit Endostatin,ES ELISA Kit |
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| GA-E0071RB-96T | GenAsia Biotech | 96T | EUR 524 |
Mouse ES-Ab ELISA Kit |
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| EME0181 | Abclonal | 96Tests | EUR 521 |
Porcine ES-Ab ELISA Kit |
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| EPE0181 | Abclonal | 96Tests | EUR 521 |
Rat ES-Ab ELISA Kit |
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| ERE0181 | Abclonal | 96Tests | EUR 521 |
Rabbit ES-Ab ELISA Kit |
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| ERTE0181 | Abclonal | 96Tests | EUR 521 |
Mouse Endostatin(ES)ELISA Kit |
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| GA-E0459MS-48T | GenAsia Biotech | 48T | EUR 336 |
Mouse Endostatin(ES)ELISA Kit |
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| GA-E0459MS-96T | GenAsia Biotech | 96T | EUR 534 |
Rat Endostatin(ES)ELISA Kit |
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| GA-E0475RT-48T | GenAsia Biotech | 48T | EUR 317 |
Rat Endostatin(ES)ELISA Kit |
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| GA-E0475RT-96T | GenAsia Biotech | 96T | EUR 496 |
Human Endostatin(ES)ELISA Kit |
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| GA-E1729HM-48T | GenAsia Biotech | 48T | EUR 289 |
Human Endostatin(ES)ELISA Kit |
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| GA-E1729HM-96T | GenAsia Biotech | 96T | EUR 466 |
Anserini ES-Ab ELISA Kit |
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| EAE0181 | Abclonal | 96Tests | EUR 521 |
Guinea Pig ES ELISA Kit |
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| EGE0010 | Abclonal | 96Tests | EUR 521 |
Guinea Pig ES ELISA Kit |
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| EGE0027 | Abclonal | 96Tests | EUR 521 |
Guinea Pig ES ELISA Kit |
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| EGE0121 | Abclonal | 96Tests | EUR 521 |
Guinea Pig ES ELISA Kit |
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| EGE0321 | Abclonal | 96Tests | EUR 521 |
Goat ES-Ab ELISA Kit |
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| EGTE0181 | Abclonal | 96Tests | EUR 521 |
Canine ES-Ab ELISA Kit |
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| ECE0181 | Abclonal | 96Tests | EUR 521 |
Human ES-Ab ELISA Kit |
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| EHE0181 | Abclonal | 96Tests | EUR 521 |
Bovine ES-Ab ELISA Kit |
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| EBE0181 | Abclonal | 96Tests | EUR 521 |
Human Endostatin,ES ELISA Kit |
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| 201-12-1713 | SunredBio | 96 tests | EUR 440 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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Rat Endostatin ELISA Kit (ES) |
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| RK03633 | Abclonal | 96 Tests | EUR 521 |
Mouse ES(Endostatin) ELISA Kit |
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| EM1009 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.469 ng/ml |
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Mouse Es(Estrogen) ELISA Kit |
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| EM1501 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml |
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Rat ES(Endostatin) ELISA Kit |
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| ER0930 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 18.75pg/ml |
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Bovine Es(Estrogen) ELISA Kit |
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| EB0091 | FN Test | 96T | EUR 567.6 |
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Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Cattle;Sensitivity: 9.375pg/ml |
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Human ES(Endostatin) ELISA Kit |
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| EH0119 | FN Test | 96T | EUR 524.1 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml |
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Human Endostatin (ES) ELISA Kit |
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| CEA542Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4253.72 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Human Endostatin (ES) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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Human Endostatin (ES) ELISA Kit |
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| CEA542Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 437.95 |
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Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Human Endostatin (ES) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. |
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Aberrant Early Growth of Individual Trigeminal Sensory and Motor Axons in a Series of Mouse Genetic Models of 22q11.2 Deletion Syndrome
- We identified divergent modes of initial axon growth that prefigure disrupted differentiation of the trigeminal nerve (CN V), a cranial nerve essential for suckling, feeding and swallowing (S/F/S), a key innate behavior compromised in multiple genetic developmental disorders including DiGeorge/22q11.2 Deletion Syndrome (22q11.2 DS). We combined rapid in vivo labeling of single CN V axons in LgDel+/- mouse embryos, a genomically accurate 22q11.2DS model, and 3-dimensional imaging to identify and quantify phenotypes that could not be resolved using existing methods.
- We assessed these phenotypes in three 22q11.2-related genotypes to determine whether individual CN V motor and sensory axons wander, branch and sprout aberrantly in register with altered anterior-posterior hindbrain patterning and gross morphological disruption of CN V seen in LgDel+/-. In the additional 22q11.2-related genotypes: Tbx1+/-, Ranbp1-/-, Ranbp1+/-, and LgDel+/-:Raldh2+/-; axon phenotypes are seen when hindbrain patterning and CN V gross morphology is altered, but not when it is normal or restored toward WT.
- This disordered growth of CN V sensory and motor axons, whose appropriate targeting is critical for optimal S/F/S, may be an early, critical determinant of imprecise innervation leading to inefficient oropharyngeal function associated with 22q11.2 deletion from birth onward.
A Faster and More Accurate Algorithm for Calculating Population Genetics Statistics Requiring Sums of Stirling Numbers of the First Kind
Ewen’s sampling formula is a foundational theoretical result that connects probability and number theory with molecular genetics and molecular evolution; it was the analytical result required for testing the neutral theory of evolution, and has since been directly or indirectly utilized in a number of population genetics statistics.
Ewen’s sampling formula, in turn, is deeply connected to Stirling numbers of the first kind. Here, we explore the cumulative distribution function of these Stirling numbers, which enables a single direct estimate of the sum, using representations in terms of the incomplete beta function.
This estimator enables an improved method for calculating an asymptotic estimate for one useful statistic, Fu’s Fs By reducing the calculation from a sum of terms involving Stirling numbers to a single estimate, we simultaneously improve accuracy and dramatically increase speed
Quantitative genetic architecture of adaptive phenology traits in the deciduous tree, Populus trichocarpa (Torr. and Gray)
In a warming climate, the ability to accurately predict and track shifting environmental conditions will be fundamental for plant survival. Environmental cues define the transitions between growth and dormancy as plants synchronise development with favourable environmental conditions, however these cues are predicted to change under future climate projections which may have profound impacts on tree survival and growth.
Here, we use a quantitative genetic approach to estimate the genetic basis of spring and autumn phenology in Populus trichocarpa to determine this species capacity for climate adaptation. We measured bud burst, leaf coloration, and leaf senescence traits across two years (2017-2018) and combine these observations with measures of lifetime growth to determine how genetic correlations between phenology and growth may facilitate or constrain adaptation. Timing of transitions differed between years, although we found strong cross year genetic correlations in all traits, suggesting that genotypes respond in consistent ways to seasonal cues.
Spring and autumn phenology were correlated with lifetime growth, where genotypes that burst leaves early and shed them late had the highest lifetime growth. We also identified substantial heritable variation in the timing of all phenological transitions (h2 = 0.5-0.8) and in lifetime growth (h2 = 0.8).
The combination of additive variation and favourable genetic correlations in phenology traits suggests that populations of cultivated varieties of P. Trichocarpa may have the capability to adapt their phenology to climatic changes without negative impacts on growth
Multiplex gRNA Kit + EF1-T7-hspCas9-H1-gRNA linearized SmartNuclease vector |
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| CAS700A-KIT | SBI | 10 rxn | EUR 1132 |
Multiplex gRNA Kit + CAG-T7-hspCas9-H1-gRNA linearized SmartNuclease vector |
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| CAS720A-KIT | SBI | 10 rxn | EUR 1132 |
Multiplex gRNA Kit + CMV-T7-hspCas9-H1-gRNA linearized SmartNuclease vector |
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| CAS740A-KIT | SBI | 10 rxn | EUR 1132 |
T7 gRNA SmartNuclease Synthesis Kit (includes CAS510A-1 & T7 IVT synthesis reagents) |
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| CAS510A-KIT | SBI | 1 Kit | EUR 805 |
Cas9 Nickase: CMV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
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| CASLV200PA-KIT | SBI | 1 Kit | EUR 1132 |
Cas9 Nickase: CMV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
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| CASLV205PA-KIT | SBI | 1 Kit | EUR 1132 |
Cas9 Nickase: MSCV-hspCas9(D10A)-T2A-Puro SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
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| CASLV220PA-KIT | SBI | 1 Kit | EUR 1132 |
Cas9 Nickase: MSCV-hspCas9(D10A)-EF1-GFP SmartNickase Lentivector Plasmid + LentiStarter Packaging Kit |
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| CASLV225PA-KIT | SBI | 1 Kit | EUR 1132 |
Multiplex gRNA Kit + Cas9 Nickase: EF1-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector |
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| CAS750A-KIT | SBI | 10 rxn | EUR 1132 |
Multiplex gRNA Kit + Cas9 Nickase: CAG-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector |
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| CAS770A-KIT | SBI | 10 rxn | EUR 1132 |
Multiplex gRNA Kit + Cas9 Nickase: CMV-T7-hspCas9-nickase-H1-gRNA linearized SmartNickase vector |
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| CAS790A-KIT | SBI | 10 rxn | EUR 1132 |
Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)] |
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| CAS9LIG-KIT | SBI | 1 Kit | EUR 153 |
PinPoint-FC 293T Platform Kit for Targeted Gene Insertion (includes PIN320A-1, PIN200A-1, PIN510A-1 & PIN600A-1) |
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| PIN320A-KIT | SBI | 1 Kit | EUR 4941 |
PinPoint-FC Murine iPSC Platform Kit for Targeted Gene Insertion (includes PIN340iPS-1, PIN200A-1, PIN510A-1 & PIN600A-1) |
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| PIN340iPS-KIT | SBI | 1 Kit | EUR 4941 |
AAVS1 Safe Harbor Targeting Vector 2.0 - All-Purpose Donor (AAVS1-SA-puro-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site) |
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| GE620A-KIT | SBI | 1 kit | EUR 2132 |
AAVS1 Safe Harbor Targeting Vector 2.0 - GOI Knock-in Donor (AAVS1-SA-puro-EF1-MCS), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site) |
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| GE622A-KIT | SBI | 1 kit | EUR 2132 |
AAVS1 Safe Harbor Targeting Vector 2.0 - Reporter Knock-in Donor (AAVS1-SA-puro-MCS-GFP), Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector) and GE640PR-1 (Junction PCR Primer Mix to confirm AAVS1 integration site) |
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| GE624A-KIT | SBI | 1 kit | EUR 2132 |
vWF Acty. Kit |
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| ABP-ACT-KIT | Abpcorp | 12 x 8 microwells | EUR 428 |
vWF Ant. Kit |
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| ABP-TOT-KIT | Abpcorp | 12 x 8 microwells | EUR 394 |
hspCas9 AAVS1 Safe Harbor Knock-in Donor (AAVS1-SA-puro-EF1-hspCas9) |
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| CAS620A-KIT | SBI | 1 kit | EUR 2152 |
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Description: Complete Kit with CAS601A-1 (Cas9 SmartNuclease AAVS1-gRNA Targeting Vector), CAS640PR-1 (Junction PCR Primer Mix to confirm Cas9 integration site), and CAS9-PR-1 (PCR primers to confirm Cas9 expression) |
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PinPoint-FC System for Platform Cell Line Generation & Retargeting (includes PIN300A-1, FC200PA-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
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| PIN300A-KIT | SBI | 1 Kit | EUR 2798 |
PinPoint-HR System for Platform Cell Line Generation & Retargeting (includes PIN400A-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
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| PIN400A-KIT | SBI | 1 Kit | EUR 2798 |
PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, GE601A-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
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| PIN410A-KIT | SBI | 1 Kit | EUR 4335 |
PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, CAS601A-1, PIN200A-1, PIN510A-1, & PIN600A-1) |
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| PIN412A-KIT | SBI | 1 Kit | EUR 4335 |
PrecisionX Multiplex gRNA Cloning Kit |
|||
| CAS9-GRNA-KIT | SBI | 10 rxn | EUR 445 |
mRNAExpress mRNA Synthesis kit (5 reactions) |
|||
| MR-KIT-1 | SBI | 5 reactions | EUR 1152 |
ExoAb Antibody Kit (CD9, CD63, CD81, Hsp70 antibodies, rabbit anti-human) with goat anti-rabbit HRP secondary antibody |
|||
| EXOAB-KIT-1 | SBI | 25 ul each | EUR 627 |
CLOuD9 Gene Expression Regulation Kit (includes 10 ug each of dCas9-PYL1 and dCas9-ABI1 lentivectors, and 100 ul of 0.5M Inducer Agent) |
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| CASCL9-100A-KIT | SBI | 1 Kit | EUR 1132 |
AXYGEN® AXYPET® PRO STARTER KIT: 4 PIPETTORS, PLEXI STAND, SAMPLE TIPS |
|||
| AP-STR-KIT-P | CORNING | 1/pk | EUR 721 |
|
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
|||
AXYPET STARTER KIT 1 AP-20, AP-200 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS |
|||
| AP-STR-KIT-1 | CORNING | 1/pk | EUR 355 |
|
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
|||
AXYPET STARTER KIT 2 AP-10, AP-100 & AP-1000 WITH ADDITIONAL FREE RACKS OF AXYGEN PIPETTE TIPS |
|||
| AP-STR-KIT-2 | CORNING | 1/pk | EUR 367 |
|
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller |
|||
Human Kit ELISA Kit |
|||
| ELA-E0121h | Lifescience Market | 96 Tests | EUR 824 |
ELISA kit for Pregnenolone Kit |
|||
| E-EL-0086 | Elabscience Biotech | 1 plate of 96 wells | EUR 377 |
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Description: A competitive ELISA kit for quantitative measurement of Pregnenolone Kit in samples from Serum, Plasma, Cell supernatant |
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Anti-c-Kit/Kit Antibody |
|||
| A01335-1 | BosterBio | 100ug/vial | EUR 334 |
Kit ELISA Kit (Mouse) (OKBB01105) |
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| OKBB01105 | Aviva Systems Biology | 96 Wells | EUR 505 |
|
Description: Description of target: SCFR(Mast/stem cell growth factor receptor), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a protein that in humans is encoded by the KIT gene. KIT was first described as the cellular homolog of the feline sarcoma viral oncogene v-kit. The KIT gene is mapped on 4q12. Kit was expressed on the surface of germ cells up to the pachytene stage. Signaling from the KIT receptor tyrosine kinase is essential for primordial germ cell growth both in vivo and in vitro. Determination of the KIT effectors acting in primordial germ cells has been hampered by the lack of effective methods to manipulate easily gene expression in these cells.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml |
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KIT ELISA Kit (Human) (OKCD06003) |
|||
| OKCD06003 | Aviva Systems Biology | 96 Wells | EUR 648 |
|
Description: Description of target: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.61ng/mL |
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KIT ELISA Kit (Mouse) (OKCD06004) |
|||
| OKCD06004 | Aviva Systems Biology | 96 Wells | EUR 779 |
|
Description: Description of target: The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Mouse;Application: ELISA;Assay info: ;Sensitivity: < 0.063ng/mL |
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KIT ELISA Kit (Human) (OKAN04574) |
|||
| OKAN04574 | Aviva Systems Biology | 96 Wells | EUR 792 |
|
Description: Description of target: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.61 ng/mL |
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KIT ELISA Kit (Bovine) (OKEH07314) |
|||
| OKEH07314 | Aviva Systems Biology | 96 Wells | EUR 1092 |
|
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.15ng/mL |
|||
KIT ELISA Kit (Chicken) (OKEH07315) |
|||
| OKEH07315 | Aviva Systems Biology | 96 Wells | EUR 1184 |
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Description: Description of target: ;Species reactivity: Chicken;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.15ng/mL |
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KIT ELISA Kit (Dog) (OKEH07316) |
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| OKEH07316 | Aviva Systems Biology | 96 Wells | EUR 1184 |
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Description: Description of target: ;Species reactivity: Dog;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.15ng/mL |
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KIT ELISA Kit (Pig) (OKEH07317) |
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| OKEH07317 | Aviva Systems Biology | 96 Wells | EUR 1092 |
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Description: Description of target: ;Species reactivity: Pig;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.15ng/mL |
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Human KIT/SCFR ELISA kit |
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| LF-EK50791 | Abfrontier | 1×96T | EUR 648 |
ELISA kit for Mouse Asprosin Kit |
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| KTE71624-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Mouse Asprosin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Mouse Asprosin Kit |
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| KTE71624-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Mouse Asprosin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Mouse Asprosin Kit |
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| KTE71624-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Mouse Asprosin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for BH4 (Tetrahydrobiopterin) Kit |
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| E-EL-0110 | Elabscience Biotech | 1 plate of 96 wells | EUR 377 |
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Description: A competitive ELISA kit for quantitative measurement of BH4 (Tetrahydrobiopterin) Kit in samples from Serum, Plasma, Cell supernatant |
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ELISA kit for BH2 (Dihydrobiopterin) Kit |
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| E-EL-0111 | Elabscience Biotech | 1 plate of 96 wells | EUR 377 |
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Description: A competitive ELISA kit for quantitative measurement of BH2 (Dihydrobiopterin) Kit in samples from Serum, Plasma, Cell supernatant |
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Cow Kit ligand (KITLG) ELISA Kit |
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| abx511856-96tests | Abbexa | 96 tests | EUR 911 |
Chicken Kit ligand (KITLG) ELISA Kit |
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| abx511857-96tests | Abbexa | 96 tests | EUR 911 |
Dog Kit ligand (KITLG) ELISA Kit |
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| abx511858-96tests | Abbexa | 96 tests | EUR 911 |
Mouse Kit ligand (KITLG) ELISA Kit |
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| abx511860-96tests | Abbexa | 96 tests | EUR 668 |
Pig Kit ligand (KITLG) ELISA Kit |
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| abx511861-96tests | Abbexa | 96 tests | EUR 911 |
Rat Kit ligand (KITLG) ELISA Kit |
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| abx511862-96tests | Abbexa | 96 tests | EUR 668 |
Human KIT/SCFR PicoKine ELISA Kit |
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| EK0835 | BosterBio | 96 wells | EUR 425 |
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Description: For quantitative detection of human KIT in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
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Mouse Kit Ligand, Kitl ELISA Kit |
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| DEIA140 | Creative Diagnostics | 10 plates | EUR 2495 |
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Description: Mouse Kitl ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant SCF in a sandwich ELISA format within the range of 32-5,250 pg/mL. Using the ELISA protocol described below, this kit provides sufficient reagents to assay Kitl in approximately 1,500 ELISA plate wells. |
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Human Kit Ligand, KitLG ELISA Kit |
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| DEIA141 | Creative Diagnostics | 10 plates | EUR 2495 |
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Description: Human KITLG ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant KITLG in a sandwich ELISA format within the range of 16-2,000 pg/mL. Using the ELISA protocol described below, this kit provides sufficient reagents to assay KITLG in approximately 1,000 ELISA plate wells |
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Rat Kit Ligand, Kitlg ELISA Kit |
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| DEIA142 | Creative Diagnostics | 10 plates | EUR 2495 |
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Description: The Human DKK1 ELISA kit is for the quantitative determination of Human DKK1.;This ELISA kit contains the basic components required for the development of sandwich ELISAs. Each kit contains sufficient materials to run ELISAs on five 96-well plates. |
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MULTIPLEX KIT PCR MASTITIS PCR kit |
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| PCR-MPX218-48D | Bioingentech | 50T | EUR 453 |
MULTIPLEX KIT PCR MASTITIS PCR kit |
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| PCR-MPX218-96D | Bioingentech | 100T | EUR 572 |
Bovine KITLG/ Kit ligand ELISA Kit |
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| E0164Bo | Sunlong | 1 Kit | EUR 717 |
Rat Kitlg/ Kit ligand ELISA Kit |
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| E0545Ra | Sunlong | 1 Kit | EUR 546 |
Human KITLG/ Kit ligand ELISA Kit |
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| E1378Hu | Sunlong | 1 Kit | EUR 537 |
Mouse Kitlg/ Kit ligand ELISA Kit |
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| E1654Mo | Sunlong | 1 Kit | EUR 546 |
Human Kit ligand (KITLG) ELISA Kit |
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| abx253483-96tests | Abbexa | 96 tests | EUR 668 |
KIT/SCFR ELISA Kit (Human) (OKBB00447) |
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| OKBB00447 | Aviva Systems Biology | 96 Wells | EUR 505 |
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Description: Description of target: SCFR (Mast/stem cell growth factor receptor), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a protein that in humans is encoded by the KIT gene. KIT was first described as the cellular homolog of the feline sarcoma viral oncogene v-kit. The KIT gene is mapped on 4q12. Kit was expressed on the surface of germ cells up to the pachytene stage. Signaling from the KIT receptor tyrosine kinase is essential for primordial germ cell growth both in vivo and in vitro. Determination of the KIT effectors acting in primordial germ cells has been hampered by the lack of effective methods to manipulate easily gene expression in these cells.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL |
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ELISA kit for Human Osteocalcin Kit |
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| KTE62822-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Human Osteocalcin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Osteocalcin Kit |
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| KTE62822-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Human Osteocalcin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Osteocalcin Kit |
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| KTE62822-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Human Osteocalcin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Tryptophan Kit |
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| KTE63056-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Human Tryptophan Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Tryptophan Kit |
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| KTE63056-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Human Tryptophan Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Tryptophan Kit |
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| KTE63056-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Human Tryptophan Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Rat Amylin Kit |
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| KTE101169-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Rat Amylin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Chicken IgG Kit |
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| KTE30183-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Chicken IgG Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Chicken IgG Kit |
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| KTE30183-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Chicken IgG Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Chicken IgG Kit |
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| KTE30183-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Chicken IgG Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Chicken IgM Kit |
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| KTE30184-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Chicken IgM Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Chicken IgM Kit |
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| KTE30184-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Chicken IgM Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Chicken IgM Kit |
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| KTE30184-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Chicken IgM Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Bovine Albumin Kit |
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| KTE10443-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Bovine Albumin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Bovine Albumin Kit |
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| KTE10443-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Bovine Albumin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Bovine Albumin Kit |
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| KTE10443-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Bovine Albumin Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Sheep Brucella Kit |
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| KTE110085-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Sheep Brucella Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Sheep Brucella Kit |
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| KTE110085-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Sheep Brucella Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Sheep Brucella Kit |
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| KTE110085-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Sheep Brucella Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Escherichia Kit |
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| KTE20145-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Canine Escherichia Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Escherichia Kit |
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| KTE20145-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Canine Escherichia Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Escherichia Kit |
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| KTE20145-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Canine Escherichia Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Campylobacter Kit |
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| KTE20147-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Canine Campylobacter Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Campylobacter Kit |
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| KTE20147-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2252 |
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Description: Quantitative sandwich ELISA for measuring Canine Campylobacter Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Campylobacter Kit |
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| KTE20147-96T | Abbkine | 96T | EUR 572 |
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Description: Quantitative sandwich ELISA for measuring Canine Campylobacter Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Canine Leptospirosis Kit |
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| KTE20157-48T | Abbkine | 48T | EUR 354 |
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Description: Quantitative sandwich ELISA for measuring Canine Leptospirosis Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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