Investigating genetic correlation and causality between – Informed Choice about Cancer Screening

Investigating genetic correlation and causality between nicotine dependence and ADHD in a broader psychiatric context

People with attention-deficit/hyperactivity disorder (ADHD) or other psychiatric disorders show high rates of nicotine dependence (ND). This comorbidity might be (partly) explained by shared genetic factors. Genetic correlations between ND and ADHD (or other psychiatric disorders) have not yet been estimated.

A significant genetic correlation might indicate genetic overlap, but could also reflect a causal relationship. In the present study we investigated the genetic correlation (with LD score regression analyses) between ND and ADHD, as well as between ND and other major psychiatric conditions (major depressive disorder, schizophrenia, anxiety, bipolar disorder, autism spectrum, anorexia nervosa, and antisocial behavior) based on the summary statistics of large Genome Wide Association studies.

We explored the causal nature of the relationship between ND and ADHD using two-sample Mendelian randomization. We found a high genetic correlation between ND and ADHD (r_g = .53, p = 1.85 × 10^-13 ), and to a lesser extent also between ND-major depressive disorder (r_g = .42, p = 3.6 × 10^-11 ) and ND-schizophrenia (r_g = .18, p = 1.1 × 10^-3 ). We did not find evidence for a causal relationship from liability for ADHD to ND (which could be due to a lack of power). The strong genetic correlations might reflect different phenotypic manifestations of (partly) shared underlying genetic vulnerabilities.

Combined with the lack of evidence for a causal relationship from liability for ADHD to ND, these findings stress the importance to further investigate the underlying genetic vulnerability explaining co-morbidity in psychiatric disorders.

30 nm DOPC Nanodisc
ND-OCGS-30	ProFoldin	90 mg	EUR 282.18
Description: This product includes 2 ml of 5 mg/ml lipids composed of DOPC:Cholesterol: DSPE-PEG2000 and 40 mg/ml SMA copolymer 2:1 in 0.1 M TrisHCl, pH 7.6.

DiagNano Fluorophore Labeled Gold Nanoparticles, 30 nm
GFL-30	Creative Diagnostics	1 mL	EUR 1263.6

DiagNano Gold Nanoparticle Passive Conjugation Kit, 30 nm
GPK-30	Creative Diagnostics	1 kit	EUR 858

Normal Chicken Serum \| RS-30-100ML
RS-30-100ML	Immunology Consultants Laboratory	100 mL	EUR 243
Description: Normal Chicken Serum \| RS-30-100ML \| Immunology Consultants Laboratory Species Reactivity: Chicken Format: Serum Product Type: Isotype Control Antibody clonality: Polyclonal

Poly-L-Lysine hydrochloride (MW: >30 kda)
SP-101951-30	Alpha Diagnostics	25 mg	EUR 169.2

Custom Anti-Peptide antibodies (peptide synthesis up to 30-aa, conjugation, 2 rabbits, ELISA)
ABPEP-30	Alpha Diagnostics	1	EUR 2389.2

30 bp random library with flanking sequence; DNA aptamer
DAL-N-30	Alpha Diagnostics	100 ug	EUR 416.4

DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 30 nm
GCK-M-30	Creative Diagnostics	1 kit	EUR 908.4

DiagNano Fluorophore Labeled Gold Nanoparticles, 30 nm, Cellular Uptake
GFL-30-CU	Creative Diagnostics	1mL	EUR 1638

ELISA Microplate Washer Automated (#MPW-30) bottle set (3 bottles and cap assembly)
MPW-30-SET	Alpha Diagnostics	1	EUR 489.6

AXYGEN® 30-WELL COMB FOR USE WITH 20 CM GEL BOX, 1.0 MM THICKNESS
HGB20-30-1	CORNING	1/pk	EUR 82.8
Description: Lab Equipment; Axygen Branded EQ

Antisauvagine-30
B5253-1	ApexBio	1 mg	EUR 876

RTC-30
HY-124669	MedChemExpress	10mM/1mL	EUR 1521.6

pQE-30
PVT0519	Lifescience Market	2 ug	EUR 289.2

RV (Rubella Antibody IgG) ELISA test
30	Biobase	96T/Box	Ask for price

Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgG)

Cellulose, microcrystalline powder, 50 micron
GV0115-100G	Glentham Life Sciences	100 g	EUR 60

Cellulose, microcrystalline powder, 50 micron
GV0115-1KG	Glentham Life Sciences	1 kg	EUR 141.6

Cellulose, microcrystalline powder, 50 micron
GV0115-250G	Glentham Life Sciences	250 g	EUR 74.4

Cellulose, microcrystalline powder, 50 micron
GV0115-500G	Glentham Life Sciences	500 g	EUR 98.4

Cellulose, microcrystalline powder, 90 micron
GV9019-100G	Glentham Life Sciences	100 g	EUR 60

Cellulose, microcrystalline powder, 90 micron
GV9019-1KG	Glentham Life Sciences	1 kg	EUR 141.6

Cellulose, microcrystalline powder, 90 micron
GV9019-250G	Glentham Life Sciences	250 g	EUR 74.4

Cellulose, microcrystalline powder, 90 micron
GV9019-25G	Glentham Life Sciences	25 g	EUR 50.4

Cellulose, microcrystalline powder, 90 micron
GV9019-500G	Glentham Life Sciences	500 g	EUR 98.4

Sieve Brass 200mm 25 Micron
200BIW025	Scientific Laboratory Supplies	EACH	EUR 475.38

Sieve Brass 200mm 71 Micron
200BIW071	Scientific Laboratory Supplies	EACH	EUR 111.72

Acrylamide Solution 30%
A067-1L	TOKU-E	1 L	EUR 123.6

Acrylamide Solution 30%
A067-500Ml	TOKU-E	500 ml	EUR 85.2

Neuromedin (B-30)
5-01596	CHI Scientific	4 x 1mg	Ask for price

rHu gACRP-30
AK9075-0005	Akron Biotech	5µg	Ask for price

rHu gACRP-30
AK9075-0025	Akron Biotech	25µg	Ask for price

rHu gACRP-30
AK9075-0100	Akron Biotech	100µg	Ask for price

rHu gACRP-30
AK9075-1000	Akron Biotech	1mg	Ask for price

Hydrogen peroxide 30%
HC4060	Bio Basic	500ml	EUR 94.8

Hydrogen peroxide, 30%
GE1911-100ML	Glentham Life Sciences	100 ml	EUR 55.2

Hydrogen peroxide, 30%
GE1911-500ML	Glentham Life Sciences	500 ml	EUR 74.4

AQEE-30 (human)
H-7274.0500	Bachem	0.5mg	EUR 698.4
Description: Sum Formula: C157H252N48O56; CAS# [160046-70-8] net

AQEE-30 (human)
H-7274.1000	Bachem	1.0mg	EUR 1305.6
Description: Sum Formula: C157H252N48O56; CAS# [160046-70-8] net

pQE-30 UA
PVT13414	Lifescience Market	2 ug	EUR 444

pETM- 30 Plasmid
PVT0371	Lifescience Market	2 ug	EUR 390

Statebourne Cryostor 30
MOL3100	Scientific Laboratory Supplies	EACH	EUR 5410.44

450ML AcrylaGel 30%
NAT1116	Scientific Laboratory Supplies	450ML	EUR 78.66

1L AcrylaGel 30%
NAT1118	Scientific Laboratory Supplies	1L	EUR 133.38

450ML ProtoGel (30%)
NAT1258	Scientific Laboratory Supplies	450ML	EUR 82.08

1L ProtoGel (30%)
NAT1260	Scientific Laboratory Supplies	1L	EUR 135.66

Reservoir 30 litres
WAT2140	Scientific Laboratory Supplies	EACH	EUR 976.98

Reservoir 30 litres
WAT2160	Scientific Laboratory Supplies	EACH	EUR 976.98

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening
M3-L18SP-400/25-IN1	MiTeGen	20 MOUNTS	EUR 112
Description: Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening

Sterile filtered mouse serum, 0.2 micron
SM30-0050	Equitech	50 ml	EUR 293.28

Sterile filtered mouse serum, 0.2 micron
SM30-0100	Equitech	100 ml	EUR 402.48

Sterile filtered mouse serum, 0.2 micron
SM30-0500	Equitech	500 ml	EUR 603.72

Sterile filtered mouse serum, 0.2 micron
SM30-3000	Equitech	3 L	Ask for price

Sterile filtered feline serum, 0.2 micron
SF30-0100	Equitech	100 ml	EUR 603.72

Sterile filtered feline serum, 0.2 micron
SF30-0500	Equitech	500 ml	EUR 1404

Sterile filtered goat serum, 0.2 micron
SG30-0100	Equitech	100 ml	EUR 202.8

Sterile filtered hamster serum, 0.2 micron
SHA30-0050	Equitech	50 ml	EUR 388.44

Sterile filtered hamster serum, 0.2 micron
SHA30-0100	Equitech	100 ml	EUR 452.4

Sterile filtered hamster serum, 0.2 micron
SHA30-0500	Equitech	500 ml	EUR 865.8

Sterile filtered donkey serum, 0.2 micron
SD30-0100	Equitech	100 ml	EUR 202.8

Sterile filtered donkey serum, 0.2 micron
SD30-0500	Equitech	500 ml	EUR 263.64

Sterile filtered equine serum, 0.2 micron
SE30-0100	Equitech	100 ml	EUR 202.8

Sterile filtered equine serum, 0.2 micron
SE30-0500	Equitech	500 ml	EUR 263.64

Sterile filtered calf serum, 0.2 micron
SBCU30-0100	Equitech	100 ml	EUR 179.4

Sterile filtered calf serum, 0.2 micron
SBCU30-0500	Equitech	500 ml	EUR 205.92

Sterile filtered bovine serum, 0.2 micron
SBSU30-0100	Equitech	100 ml	EUR 179.4

Sterile filtered bovine serum, 0.2 micron
SBSU30-0500	Equitech	500 ml	EUR 205.92

Sterile filtered chicken serum, 0.2 micron
SC30-0100	Equitech	100 ml	EUR 195

Sterile filtered chicken serum, 0.2 micron
SC30-0500	Equitech	500 ml	EUR 234

Sterile filtered canine serum, 0.2 micron
SCA30-0050	Equitech	50 ml	EUR 293.28

Sterile filtered canine serum, 0.2 micron
SCA30-0100	Equitech	100 ml	EUR 383.76

Sterile filtered canine serum, 0.2 micron
SCA30-0500	Equitech	500 ml	EUR 723.84

Sterile filtered porcine serum, 0.2 micron
SP30-0100	Equitech	100 ml	EUR 209.04

Sterile filtered porcine serum, 0.2 micron
SP30-0500	Equitech	500 ml	EUR 249.6

Sterile filtered rabbit serum, 0.2 micron
SR30-0100	Equitech	100 ml	EUR 207.48

Sterile filtered rabbit serum, 0.2 micron
SR30-0500	Equitech	500 ml	EUR 277.68

Sterile filtered rat serum, 0.2 micron
SRT30-0050	Equitech	50 ml	EUR 308.88

Sterile filtered rat serum, 0.2 micron
SRT30-0100	Equitech	100 ml	EUR 383.76

Sterile filtered rat serum, 0.2 micron
SRT30-0500	Equitech	500 ml	EUR 652.08

Sterile filtered sheep serum, 0.2 micron
SS30-0100	Equitech	100 ml	EUR 216.84

Sterile filtered sheep serum, 0.2 micron
SS30-0500	Equitech	500 ml	EUR 283.92

MicroMount Small Aperture Assortment -5 each of 10, 20, 30 and 50 micron aperture mounts; mounted on 18 mm rods
M2-L18SP-A1	MiTeGen	20 MOUNTS	EUR 112

Description: MicroMount Small Aperture Assortment -5 each of 10, 20, 30 and 50 micron aperture mounts; mounted on 18 mm rods

Indexed MicroMesh; box of 20 with 300 micron Diameter and 25 micron mesh Opening, Flat Top
M3-L18SP-300/25-IN1	MiTeGen	20 MOUNTS	EUR 112
Description: Indexed MicroMesh; box of 20 with 300 micron Diameter and 25 micron mesh Opening, Flat Top

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening, Square Openings
M3-L18SP-400/25-IN2	MiTeGen	20 MOUNTS	EUR 112
Description: Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening, Square Openings

Sterile filtered guinea pig serum, 0.2 micron
SGP30-0050	Equitech	50 ml	EUR 321.36

Sterile filtered guinea pig serum, 0.2 micron
SGP30-0100	Equitech	100 ml	EUR 375.96

Sterile filtered guinea pig serum, 0.2 micron
SGP30-0500	Equitech	500 ml	EUR 708.24

Sterile filtered Cynomolgus monkey serum, 0.2 micron
SCM30-0050	Equitech	50 ml	EUR 1071.72

Sterile filtered Cynomolgus monkey serum, 0.2 micron
SCM30-0100	Equitech	100 ml	Ask for price

Sterile filtered Cynomolgus monkey serum, 0.2 micron
SCM30-0500	Equitech	500 ml	Ask for price

Sterile filtered newborn calf serum, 0.2 micron
SNBU30-0100	Equitech	100 ml	EUR 195

Sterile filtered newborn calf serum, 0.2 micron
SNBU30-0500	Equitech	500 ml	EUR 240.24

Sterile filtered Rhesus monkey serum, 0.2 micron
SRM30-0025	Equitech	25ml	EUR 723.84

Sterile filtered Rhesus monkey serum, 0.2 micron
SRM30-0050	Equitech	50 ml	EUR 1071.72

Sterile filtered Rhesus monkey serum, 0.2 micron
SRM30-0100	Equitech	100 ml	Ask for price

Sterile filtered Rhesus monkey serum, 0.2 micron
SRM30-0500	Equitech	500 ml	Ask for price

Kinesis Siltite Micron union Ferrule 0.8-0.8
CHR1931	Scientific Laboratory Supplies	EACH	EUR 143.64

Elga 10 Inch 10 Micron Optional Filter
WAT2830	Scientific Laboratory Supplies	EACH	EUR 72.96

Gold Colloid (30 nm)
62R-GC013	Fitzgerald	20 ml	EUR 184.8
Description: 30 nm Colloidal Gold particle suspension

beta - Amyloid (30 - 16)
5-00450	CHI Scientific	4 x 1mg	Ask for price

ANP (1-30), frog
5-00703	CHI Scientific	0.4 x 5mg	Ask for price

IGF-I (30-41)
5-01369	CHI Scientific	4 x 5mg	Ask for price

Neuropeptide W-30 (human)
5-01612	CHI Scientific	4 x 1mg	Ask for price

Neuropeptide W-30 (rat)
5-01613	CHI Scientific	4 x 1mg	Ask for price

PrP 27-30 antibody
20-PG73	Fitzgerald	100 ul	EUR 600
Description: Goat polyclonal PrP 27-30 antibody

PrP 27-30 antibody
20R-PG009	Fitzgerald	250 ul	EUR 418.8
Description: Goat polyclonal PrP 27-30 antibody

TFIIF RAP 30 Antibody
20-abx141315	Abbexa	EUR 444.00 EUR 727.20 EUR 360.00	100 ul 200 ul 50 ul

Tetraspanin 30 (TSPAN30) Antibody
20-abx101673	Abbexa	EUR 493.20 EUR 159.60 EUR 1378.80 EUR 678.00 EUR 376.80	100 ug 10 ug 1 mg 200 ug 50 ug

Tetraspanin 30 (TSPAN30) Antibody
20-abx178555	Abbexa	EUR 1412.40 EUR 693.60	1 mg 200 ug

Tetraspanin 30 (TSPAN30) Antibody
20-abx178556	Abbexa	EUR 1412.40 EUR 693.60	1 mg 200 ug

CGRP1 (30-37) Peptide
20-abx265404	Abbexa	EUR 493.20 EUR 794.40 EUR 376.80	10 mg 25 mg 5 mg

ANP (1-30) Peptide
20-abx265417	Abbexa	EUR 460.80 EUR 627.60 EUR 961.20	0.5 mg 1 mg 2.5 mg

Tetraspanin 30 (TSPAN30) Antibody
20-abx270043	Abbexa	EUR 560.40 EUR 644.40 EUR 326.40 EUR 978.00 EUR 427.20	100 tests 200 tests 25 tests 500 tests 50 tests

Connexin 30 (Cx30) Antibody
abx430912-200ul	Abbexa	200 ul	EUR 343.2

Tetraspanin 30 (TSPAN30) Antibody
20-abx174747	Abbexa	EUR 393.60 EUR 978.00 EUR 510.00 EUR 184.80 EUR 309.60	100 ug 1 mg 200 ug 20 ug 50 ug

Association of MAPK4 and SOX1-OT gene polymorphisms with cleft lip palate in multiplex families: A genetic study

Background. Cleft lip and palate (CLP) is a common congenital anomaly. Many genes, like MAPK4 and SOX-1OT, are associated with its etiology in different populations. High-risk markers on these gene sreported in other populations were not studied in our population. Hence, the study aimed to determine the association of MAPK4 and SOX-1OT polymorphisms in CLP in multiplex families.

Methods. Based on inclusion and exclusion criteria, we selected 20 multiplex CLP families for this case‒control study, in which the affected individuals and healthy controls selected from these families were compared. Fifty subjects affected with cleft and 38 unaffected subjects were included in the study. The polymorphisms studied for the association consisted of rs726455 and rs2969972 in the genes SOX-1 OT and MAPK4, respectively. DNA was isolated and sent for genotyping using the MassArray method. Plink, a whole-genome association analysis toolset, was used for statistical analysis.

Results. Both polymorphisms followed Hardy-Weinberg equilibrium. The rs726455 of SOX-1OT yielded a P-value of 0.983 and an allelic odds ratio (OR) of 0.983. For rs2969972 of MAPK4, the P-value was 0.04 (significant), and the allelic OR was 0.51. Minor allele frequency (MAF) in the unaffected subjects was more than the MAF in the affected subjects for rs2969972.

Conclusion. The results suggested that polymorphism rs726455 on SOX-1OT was not associated with familial cases of CLP. Since MAF in the unaffected subjects was more than the MAF-affected subjects, rs2969972 on MAPK4 is protective in the multiplex families.

Genetic Diversity and Virulence Factors of S. aureus Isolated from Food, Humans, and Animals

Staphylococcus aureus is a commensal bacterium in humans and animals able to adapt to multiple environments. The aim of this study was to compare the genetic diversity and virulence profiles of strains of S. aureus isolated from food (29 strains), humans (43 strains), and animals (8 strains). 80 lipase-producing strains belonging to a biobank of 360 isolates, identified phenotypically as S. aureus, were selected.
Confirmation of the species was made by amplifying the spA gene and 80% (64/80) of the strains were confirmed within this species. The virulence profile of each of the isolates was determined by PCR. The seA gene coding for enterotoxin A was found in 53.1% of the strains, the saK gene, which codes for Staphylokinase, was amplified in 57.8% of the strains, and, finally, the hlB gene coding for β-Hemolysin was amplified in 17.2%.
The profile of antimicrobial resistance was determined by the Kirby Bauer method showing that the strains from food presented greater resistance to erythromycin (40.7%) and ciprofloxacin (18.5%) while in strains isolated from humans were to erythromycin (48.4%) and clindamycin (21.2%). Also, in strains from animals, a high resistance to erythromycin was observed (75%).
The frequency of MRSA was 12.5% due to the presence of the mec gene and resistance to cefoxitin. Of the total strains, 68.7% were typed by PCR-RFLP of the coa gene using the AluI enzyme; derived from this restriction, 17 profiles were generated. Profile 4 (490 bp, 300 bp) was the most frequent, containing a higher number of strains with a higher number of virulence factors and antimicrobial resistance, which is associated with greater adaptation to different environments.
In this study, a wide genetic diversity of strains of S. aureus from different foods, humans, and animals was found. This demonstrates evolution, genetic versatility, and, therefore, the adaptation of this microorganism in different environments.

photo documentation system
VLBPCX4-20M	Consort	ea	EUR 7622.4

photo documentation system
VLBPCX4-20MX	Consort	ea	EUR 8128.8

photo documentation system
VLDP-HOOD	Consort	ea	EUR 6100.8

photo documentation system
VLDP17-26M	Consort	ea	EUR 9751.2

photo documentation system
VLDP17-26MX	Consort	ea	EUR 10156.8

Heidolph clamping system
509-63100-00	Scientific Laboratory Supplies	EACH	EUR 135.66

Campact Vacuum System
AC701	Scientific Laboratory Supplies	EACH	EUR 2531.94

Extractor System Option
DRY1128	Scientific Laboratory Supplies	EACH	EUR 476.52

IsoTherm-System Starter
E3880001018	Scientific Laboratory Supplies	EACH	EUR 163.02

miniONE Electrophoresis System
ELE3400	Scientific Laboratory Supplies	EACH	EUR 624.72

Disposable Bag System
H20CBS50	Scientific Laboratory Supplies	EACH	EUR 165.3

Lower cooling system
WAT4796	Scientific Laboratory Supplies	EACH	EUR 984.96

Digestive system (esophagus
GI1441	TissueArray	each	EUR 306
Description: Digestive system (esophagus, stomach, colon, rectum, liver, pancreas) cancer with matched adjacent normal tissue array, including TNM, pathology grade and clinical stage, 72 cases/144 cores, replaced by GI1441a

Digestive system (esophagus
GI701a	TissueArray	each	EUR 222
Description: Digestive system (esophagus, stomach, colon, rectum, liver, pancreas) cancer with matched adjacent normal tissue array, including TNM, pathology grade and clinical stage, 35 cases/70 cores, replacing GI701

Propane Transfer System
M-CEM-37015	MiTeGen	1 UNIT	EUR 625

Description: Propane Transfer System

Watershed System Kit
M-WS180320-1	MiTeGen	1 KIT	EUR 9296

Description: Watershed System Kit

FractionPREP Cell Fractionation system
55R-1359	Fitzgerald	50 assays	EUR 909.6
Description: Cell Fractionation system for use in the research laboratory

Fast MultiSite Mutagenesis System
abx098861-10rxns	Abbexa	10 rxns	EUR 828

myGel Mini Electrophoresis System
BM0286	GenDepot	System	EUR 741.6

cfMAX cfDNA Isolation System
CFMAX100A-1	SBI	1 Kit	EUR 574.8

mini system 7x8 cm
EHS3100-SYS	Consort	ea	EUR 524.4

EasyDip Slide Staining System
M900-12AS-ASSORTED	ScyTek Laboratories	1 Case(s)	EUR 211.2

mini system 8x10 cm
EHS1050-SYS	Consort	ea	EUR 422.4

modular system 10x10 cm
EVS1100-MULTI	Consort	ea	EUR 1436.4

modular system 20x10 cm
EVS1200-MULTI	Consort	ea	EUR 1741.2

modular system 20x20 cm
EVS1300-MULTI	Consort	ea	EUR 2349.6

vertical system 10x10 cm
EVS3100-SYS	Consort	ea	EUR 930

vertical system 20x10 cm
EVS3200-SYS	Consort	ea	EUR 1741.2

vertical system 20x20 cm
EVS3300-SYS	Consort	ea	EUR 2044.8

sequencing system 20x50 cm
ESEQ1200-SYS	Consort	ea	EUR 1842

BCIP/NBT Substrate System
GR103022	Genorise Scientific	2 x 25 mL	EUR 142.8

AP Fluorescent Substrate System
GR103053	Genorise Scientific	Each	EUR 99.6

HRP Floresce Substrate System
GR103054	Genorise Scientific	Each	EUR 99.6

96-Well Vacuum System
SD5011	Bio Basic	1 UNIT	EUR 388.86

Episomal iPSC Reprogramming System
SC900A-1	SBI	5 reactions	EUR 1161.6

amfiRivert Reverse Transcription System
R5200-050	GenDepot	50 rxns	EUR 465.6

MiniVac Waste Aspiration System
ARG1464	Scientific Laboratory Supplies	EACH	EUR 254.22

Ez C02 System Sachets
260679	Scientific Laboratory Supplies	PK20	EUR 126.54

Ez Campy System Sachets
260680	Scientific Laboratory Supplies	PK20	EUR 64.98

Ez Anaerobe Pouch System
260683	Scientific Laboratory Supplies	PK20	EUR 117.42

Dual Spot PLUS System
MIC2516	Scientific Laboratory Supplies	EACH	EUR 938.22

VeriClean Triple Bucket System
CLE9830	Scientific Laboratory Supplies	EACH	EUR 1629.06

Nalgene System 100 Cryobox
CRY8305	Scientific Laboratory Supplies	PK10	EUR 199.5

Syngene DigiGenius System DG1
ELE7500	Scientific Laboratory Supplies	EACH	EUR 2394

Syngene InGenius 3 System
ELE7540	Scientific Laboratory Supplies	EACH	EUR 4075.5

Syngene GBox F3 System
ELE7580	Scientific Laboratory Supplies	EACH	EUR 8413.2

Foot Pedal Complete System
FLY1234	Scientific Laboratory Supplies	EACH	EUR 706.8

Axygen Gel Documentation System
GD-1000	Scientific Laboratory Supplies	EACH	EUR 5947.38

Safevac Vacuum Aspiration System
SLS4950	Scientific Laboratory Supplies	EACH	EUR 1567.5

KNF SC920G Vacuum System
PUM5198	Scientific Laboratory Supplies	EACH	EUR 4664.88

myGel Mini Electrophoresis System
E1101	Benchmark Scientific	1 each	EUR 623.9

Automatic Potentiometric Titration System
TIT1030	Scientific Laboratory Supplies	EACH	EUR 5647.56

AFS-EDI SYSTEM CART
ZAFSCART2	Scientific Laboratory Supplies	EACH	EUR 800.28

Connector 5m System-POD
ZFC0NN5SQ	Scientific Laboratory Supplies	EACH	EUR 135.66

EpiSonic 2000 Sonication System
EQC-2000-1	EpiGentek	1 unit	EUR 20590.9

Digestive system tissue array
DGS2081	TissueArray	each	EUR 474
Description: Digestive system tissue array, including TNM, stage and grade, 104 cases/208 cores

Gryphon Retroviral Expression System I
ABP-RVK-10001	Allele Biotech	1 set	Ask for price

Description: PRODUCT LINE DISCONTINUED. Please contact us.

Gryphon Retroviral Expression System II
ABP-RVK-10002	Allele Biotech	1 set	Ask for price

Description: PRODUCT LINE DISCONTINUED. Please contact us.

Rabbit Reticulocyte Lysate System (untreated)
20-abx800016	Abbexa	EUR 8110.80 EUR 7108.80 EUR 5137.20	100 ml 500 ml 50 ml

data acquisition system 120 vac
D230-US	Consort	ea	EUR 2044.8

Slidefile Storage System 100 Positions
M700-100W-WHITE	ScyTek Laboratories	1 Case(s)	EUR 230.4

Stain Tray Slide Staining System
M920-1	ScyTek Laboratories	1 Clear	EUR 513.6

Stain Tray Slide Staining System
M920-2	ScyTek Laboratories	1 Black	EUR 534

HISTAR DETECTION SYSTEM Kits (OKSA11259)
OKSA11259	Aviva Systems Biology	50 Tests	EUR 678
Description: Description of target: HISTAR DETECTION SYSTEM;Species reactivity: ;Application: IHC-AFF, IHC-FFPE;Assay info: ;Sensitivity:

HISTAR DETECTION SYSTEM Kits (OKSA11260)
OKSA11260	Aviva Systems Biology	150 Tests	EUR 1602
Description: Description of target: HISTAR DETECTION SYSTEM;Species reactivity: ;Application: IHC-AFF, IHC-FFPE;Assay info: ;Sensitivity:

HISTAR DETECTION SYSTEM Kits (OKSA11261)
OKSA11261	Aviva Systems Biology	500 Tests	EUR 2422.8
Description: Description of target: HISTAR DETECTION SYSTEM;Species reactivity: ;Application: IHC-AFF, IHC-FFPE;Assay info: ;Sensitivity:

mini vertical system 10x10 cm
EVS1100-SYS	Consort	ea	EUR 727.2

mini vertical system 20x10 cm
EVS1200-SYS	Consort	ea	EUR 1030.8

maxi vertical system 20x20 cm
EVS1300-SYS	Consort	ea	EUR 1365.6

Manual Staining System (12 Wells)
IMS001	ScyTek Laboratories	1 ea.	EUR 427.2

ViraSafe Lentiviral Packaging System, Ecotropic
VPK-205	Cell Biolabs	1 kit	EUR 1069.2
Description: Our ViraSafe Lentiviral Packaging Systems contain three packaging plasmids for co-transfection with your own third generation lentiviral expression construct. If you need an expression vector as well as the packaging plasmids, consider our ViraSafe Lentiviral Expression Complete Systems. Our Ecotropic Packaging System assembles lentiviruses with an ecotropic envelope protein which will readily infect only mouse and rat cells via receptor-mediated binding, providing an additional level of safety. However, ecotropic viruses are not as stable upon freezing and will not survive ultracentrifugation procedure

ViraSafe Lentiviral Packaging System, Pantropic
VPK-206	Cell Biolabs	1 kit	EUR 1069.2
Description: Our ViraSafe Lentiviral Packaging Systems contain three packaging plasmids for co-transfection with your own third generation lentiviral expression construct. If you need an expression vector as well as the packaging plasmids, consider our ViraSafe Lentiviral Expression Complete Systems. The Pantropic Packaging System assembles VSVG-pseudotyped lentiviruses which can easily infect virtually any cells regardless of their species of origin.

Platinum Retroviral Expression System, Ecotropic
VPK-300	Cell Biolabs	1 kit	EUR 1402.8
Description: Retroviral vectors are useful for delivering genes of interest into a target cells where integration into the genome is desired. However, traditional retroviral expression technologies result in low viral titers, making gene expression studies challenging. Platinum Retroviral Expression Systems incorporate superior packaging cell lines and vector technologies to produce high-titer virus with a single plasmid transfection. This system includes our exclusive Platinum-E Packaging cell line, which contains the gag and pol genes and an ecotropic envelope protein for viral packaging. Simply clone your gene of interest into the vector provided and transfect into the packaging cells.

Platinum Retroviral Expression System, Amphotropic
VPK-301	Cell Biolabs	1 kit	EUR 1402.8
Description: Retroviral vectors are useful for delivering genes of interest into a target cells where integration into the genome is desired. However, traditional retroviral expression technologies result in low viral titers, making gene expression studies challenging. Platinum Retroviral Expression Systems incorporate superior packaging cell lines and vector technologies to produce high-titer virus with a single plasmid transfection. This system includes our exclusive Platinum-A Packaging cell line, which contains the gag and pol genes and an amphotropic envelope protein for viral packaging. Simply clone your gene of interest into the vector provided and transfect into the packaging cells.

Platinum Retroviral Expression System, Pantropic
VPK-302	Cell Biolabs	1 kit	EUR 1402.8
Description: Retroviral vectors are useful for delivering genes of interest into a target cells where integration into the genome is desired. However, traditional retroviral expression technologies result in low viral titers, making gene expression studies challenging. Platinum Retroviral Expression Systems incorporate superior packaging cell lines and vector technologies to produce high-titer virus with a single plasmid transfection. This system includes our exclusive Platinum-GP Packaging cell line which contains the gag and pol genes necessary for viral packaging. Simply clone your gene of interest into the vector provided and co-transfect into the packaging cells along with the included VSVG plasmid.

Filtration System 47mm Complete Assembly
5809/KIT	Scientific Laboratory Supplies	EACH	EUR 427.69

P-Vac Portable Vacuum System
ARG1608	Scientific Laboratory Supplies	EACH	EUR 939.36

FlexiRack Complete System with Brackets
ARG1740	Scientific Laboratory Supplies	EACH	EUR 51.41

Hirschmann Aspirette Vacuum Tweezer System
ASP1300	Scientific Laboratory Supplies	EACH	EUR 299.82

Discard System Rodwell Sentinel Ensign
AUT2006	Scientific Laboratory Supplies	EACH	EUR 1071.6

Discard System for Rodwell Monarch
AUT2008	Scientific Laboratory Supplies	EACH	EUR 849.3

Slide storing system with castor
MIC4524	Scientific Laboratory Supplies	EACH	EUR 599.64

SequaGel Sequencing System 1L Kit
NAT1136	Scientific Laboratory Supplies	1KIT	EUR 127.68

SequaGel Sequencing System 2.2L Kit
NAT1138	Scientific Laboratory Supplies	EACH	EUR 217.74

Flatbed Isoelectric focussing system 26x26cm
CSLIEF	Scientific Laboratory Supplies	EACH	EUR 3868.02

Eppendorf Concentrator plus complete system
E5305000363	Scientific Laboratory Supplies	EACH	EUR 7641.42

Electro blot Mini system 10x10cm
EBM10	Scientific Laboratory Supplies	EACH	EUR 877.8

Nugenius Gel Docu System LED
ELE0028	Scientific Laboratory Supplies	EACH	EUR 6692.94

Nugenius Gel Docu System Plus
ELE0030	Scientific Laboratory Supplies	EACH	EUR 7993.68

GeneGnome XRQ 16 bit system
ELE2116	Scientific Laboratory Supplies	EACH	EUR 9639.84

Gel Doc System EtBr Filter
ELE2500	Scientific Laboratory Supplies	EACH	EUR 6733.98

EpiNext DNA Purification HT System
P-1063-04	EpiGentek	4 ml	EUR 127.6

EpiNext DNA Purification HT System
P-1063-08	EpiGentek	8 ml	EUR 234.3

EpiNext DNA Purification HT System
P-1063-64	EpiGentek	64 ml	EUR 1103.3

EpiNext DNA Purification HT System
P-1063-X4	EpiGentek	480 ml	EUR 5052.3

Kinesis Luertight System 1/16
CHR4559	Scientific Laboratory Supplies	EACH	EUR 17.1

Kinesis LuerTight System 1/8in
CHR4561	Scientific Laboratory Supplies	EACH	EUR 17.1

Wall-Mount Flowbuddy Complete System
FLY1238	Scientific Laboratory Supplies	EACH	EUR 889.2

ECL PRIME WESTERN BLOTTING SYSTEM
GERPN2232	Scientific Laboratory Supplies	EACH	EUR 254.22

PREPAK L1 PRE-SYSTEM PACK
PRPK0L0S1SIG	Scientific Laboratory Supplies	EACH	EUR 494.76

BD600 BOD System for 6
WAT2030	Scientific Laboratory Supplies	EACH	EUR 2379.18

BD606 BOD System for 12
WAT2032	Scientific Laboratory Supplies	EACH	EUR 3887.4

Ventilator for lower cooling system
WAT4738	Scientific Laboratory Supplies	EACH	EUR 150.48

SYSTEM STAND, AFS-3/3D
ZAF3STAND	Scientific Laboratory Supplies	EACH	EUR 541.5

External Pretreatment-XL system cable
ZLXLPTCAB	Scientific Laboratory Supplies	EACH	EUR 106.02

EpiNext DNA Purification HT System
P-1063	EpiGentek	EUR 7227.06 EUR 127.60 EUR 234.30 EUR 1103.30 EUR 5052.30	480 ml 4 ml 8 ml 64 ml 480 ml

SmartSEC Single EV Isolation System
SSEC200A-1	SBI	10 rxn	EUR 391

Female reproductive system tissue array
FRS801	TissueArray	each	EUR 306
Description: Female reproductive system tissue array, with stage and grade info, 80 cases/80 cores

Nervous system tumor tissue array
GL961	TissueArray	each	EUR 306
Description: Nervous system tumor tissue array, including clinical stage and pathology grade, 48 cases/96 cores

Bone Dissociation System 5 (Osteoblasts), Rat
4-20215	CHI Scientific	ea	Ask for price

Liver Dissociation System 1 (Hepatocytes), Mouse
4-20301	CHI Scientific	ea	Ask for price

Mammary Dissociation System 3 (Epithelial), Mouse
4-20323	CHI Scientific	ea	Ask for price

Mammary Dissociation System 6 (Epithelial), Rat
4-20326	CHI Scientific	ea	Ask for price

Pancreas Dissociation System 3 (Duct), Mouse
4-20373	CHI Scientific	ea	Ask for price

Pancreas Dissociation System 8 (Duct), Rat
4-20378	CHI Scientific	ea	Ask for price

Thymus Dissociation System 2 (Epithelial), Mouse
4-20442	CHI Scientific	ea	Ask for price

Human Airway OptiTDS1: Tissue Dissociation System
4-28001	CHI Scientific	1 Kit	Ask for price

Human Airway OptiTDS2: Tissue Dissociation System
4-28002	CHI Scientific	1 Kit	Ask for price

Human Airway OptiTDS3: Tissue Dissociation System
4-28003	CHI Scientific	1 Kit	Ask for price

Human Airway OptiTDS4: Tissue Dissociation System
4-28004	CHI Scientific	1 Kit	Ask for price

Human Aorta OptiTDS: Tissue Dissociation System
4-28005	CHI Scientific	1 Kit	Ask for price

Human Artery OptiTDS: Tissue Dissociation System
4-28006	CHI Scientific	1 Kit	Ask for price

Human Bladder OptiTDS1: Tissue Dissociation System
4-28007	CHI Scientific	1 Kit	Ask for price

Human Bladder OptiTDS2: Tissue Dissociation System
4-28008	CHI Scientific	1 Kit	Ask for price

Human Bladder OptiTDS3: Tissue Dissociation System
4-28009	CHI Scientific	1 Kit	Ask for price

Human Bone OptiTDS: Tissue Dissociation System
4-28012	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS1: Tissue Dissociation System
4-28013	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS2: Tissue Dissociation System
4-28014	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS3: Tissue Dissociation System
4-28015	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS4: Tissue Dissociation System
4-28016	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS5: Tissue Dissociation System
4-28017	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS6: Tissue Dissociation System
4-28018	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS7: Tissue Dissociation System
4-28019	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS8: Tissue Dissociation System
4-28020	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS9: Tissue Dissociation System
4-28021	CHI Scientific	1 Kit	Ask for price

Human Brain OptiTDS10: Tissue Dissociation System
4-28022	CHI Scientific	1 Kit	Ask for price

Human Breast OptiTDS: Tissue Dissociation System
4-28023	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS1: Tissue Dissociation System
4-28024	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS2: Tissue Dissociation System
4-28025	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS3: Tissue Dissociation System
4-28026	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS4: Tissue Dissociation System
4-28027	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS5: Tissue Dissociation System
4-28028	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS6: Tissue Dissociation System
4-28029	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS7: Tissue Dissociation System
4-28030	CHI Scientific	1 Kit	Ask for price

Human Cancer OptiTDS8: Tissue Dissociation System
4-28031	CHI Scientific	1 Kit	Ask for price

Investigating genetic correlation and causality between nicotine dependence and ADHD in a broader psychiatric context

30 nm DOPC Nanodisc

DiagNano Fluorophore Labeled Gold Nanoparticles, 30 nm

DiagNano Gold Nanoparticle Passive Conjugation Kit, 30 nm

Normal Chicken Serum | RS-30-100ML

Poly-L-Lysine hydrochloride (MW: >30 kda)

Custom Anti-Peptide antibodies (peptide synthesis up to 30-aa, conjugation, 2 rabbits, ELISA)

30 bp random library with flanking sequence; DNA aptamer

DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 30 nm

DiagNano Fluorophore Labeled Gold Nanoparticles, 30 nm, Cellular Uptake

ELISA Microplate Washer Automated (#MPW-30) bottle set (3 bottles and cap assembly)

AXYGEN® 30-WELL COMB FOR USE WITH 20 CM GEL BOX, 1.0 MM THICKNESS

Antisauvagine-30

RTC-30

pQE-30

RV (Rubella Antibody IgG) ELISA test

Cellulose, microcrystalline powder, 50 micron

Cellulose, microcrystalline powder, 50 micron

Cellulose, microcrystalline powder, 50 micron

Cellulose, microcrystalline powder, 50 micron

Cellulose, microcrystalline powder, 90 micron

Cellulose, microcrystalline powder, 90 micron

Cellulose, microcrystalline powder, 90 micron

Cellulose, microcrystalline powder, 90 micron

Cellulose, microcrystalline powder, 90 micron

Sieve Brass 200mm 25 Micron

Sieve Brass 200mm 71 Micron

Acrylamide Solution 30%

Acrylamide Solution 30%

Neuromedin (B-30)

rHu gACRP-30

rHu gACRP-30

rHu gACRP-30

rHu gACRP-30

Hydrogen peroxide 30%

Hydrogen peroxide, 30%

Hydrogen peroxide, 30%

AQEE-30 (human)

AQEE-30 (human)

pQE-30 UA

pETM- 30 Plasmid

Statebourne Cryostor 30

450ML AcrylaGel 30%

1L AcrylaGel 30%

450ML ProtoGel (30%)

1L ProtoGel (30%)

Reservoir 30 litres

Reservoir 30 litres

Indexed MicroMesh; box of 20 with 400 micron Diameter and 25 micron mesh Opening

Sterile filtered mouse serum, 0.2 micron

Sterile filtered mouse serum, 0.2 micron

Sterile filtered mouse serum, 0.2 micron

Sterile filtered mouse serum, 0.2 micron

Sterile filtered feline serum, 0.2 micron

Sterile filtered feline serum, 0.2 micron

Sterile filtered goat serum, 0.2 micron

Sterile filtered hamster serum, 0.2 micron

Sterile filtered hamster serum, 0.2 micron

Sterile filtered hamster serum, 0.2 micron

Sterile filtered donkey serum, 0.2 micron

Sterile filtered donkey serum, 0.2 micron

Sterile filtered equine serum, 0.2 micron

Sterile filtered equine serum, 0.2 micron

Sterile filtered calf serum, 0.2 micron

Sterile filtered calf serum, 0.2 micron

Sterile filtered bovine serum, 0.2 micron

Sterile filtered bovine serum, 0.2 micron

Sterile filtered chicken serum, 0.2 micron

Sterile filtered chicken serum, 0.2 micron

Sterile filtered canine serum, 0.2 micron

Sterile filtered canine serum, 0.2 micron

Sterile filtered canine serum, 0.2 micron

Sterile filtered porcine serum, 0.2 micron

Sterile filtered porcine serum, 0.2 micron

Sterile filtered rabbit serum, 0.2 micron

Sterile filtered rabbit serum, 0.2 micron

Sterile filtered rat serum, 0.2 micron

Sterile filtered rat serum, 0.2 micron

Sterile filtered rat serum, 0.2 micron

Sterile filtered sheep serum, 0.2 micron